Lethal combination
Because the anti-diabetes drug metformin blocks the second of the two cellular pathways for NAD+ regeneration, combined metformin-syrosingopine treatment results in complete loss of the cell’s NAD+ recycling capacity. The depletion of NAD+ in turn leads to cell death, as the cancer cells are no longer able to produce sufficient energy
https://oncozine.com...s-tumor-growth/
Edited by theone, 09 January 2019 - 07:47 PM.