Stem cells could replace plastic surgery
This is great news. If stem cell therapy works and keeps hollywood stars and other rich vain people looking young (even if it is only superficial) it could really boost research and investment in the field.
Posted 25 June 2008 - 04:11 PM
Posted 25 June 2008 - 06:43 PM
Posted 26 June 2008 - 01:25 AM
Posted 26 June 2008 - 02:21 AM
Edited by caston, 26 June 2008 - 08:27 AM.
Posted 26 June 2008 - 03:43 AM
Posted 28 July 2008 - 06:48 PM
And how long should we expect those new type of cosmetics to arrive?
Posted 04 November 2008 - 12:06 AM
Posted 04 November 2008 - 12:18 AM
Posted 04 November 2008 - 04:15 AM
I could see advances in this area allowing quite inexpensive cosmetic surgery ($500 or so)
this procedure will cost approximately $5,000
Posted 04 November 2008 - 04:34 AM
Not really... $500 probably IS what it costs, just not what they charge you for it.I could see advances in this area allowing quite inexpensive cosmetic surgery ($500 or so)
this procedure will cost approximately $5,000
I guess I was only off by one order of magnitude
Posted 04 November 2008 - 08:32 AM
Posted 04 November 2008 - 02:17 PM
The woman in the article looks scary @@..
Posted 05 November 2008 - 10:06 AM
Posted 29 March 2009 - 04:27 AM
Posted 29 March 2009 - 04:42 AM
Hmm. how 'bout that? More evidence that Bush "helped" stem cell research in America?The same technique has been used in Japan for six years, initially to treat women with breast deformities caused by cancer treatment and, more recently, for cosmetic breast augmentation in healthy women.
Posted 29 March 2009 - 04:44 AM
Wow. Smaller stomach and bigger boobs? Talk about win-win.
Hmm. how 'bout that? More evidence that Bush "helped" stem cell research in America?The same technique has been used in Japan for six years, initially to treat women with breast deformities caused by cancer treatment and, more recently, for cosmetic breast augmentation in healthy women.
Posted 29 March 2009 - 05:52 AM
Posted 29 March 2009 - 07:39 AM
Wow. Smaller stomach and bigger boobs? Talk about win-win.
Posted 03 April 2009 - 12:56 AM
Posted 03 April 2009 - 01:43 AM
Edited by sentrysnipe, 03 April 2009 - 01:45 AM.
Posted 05 April 2009 - 09:11 AM
Posted 13 June 2009 - 11:08 PM
Posted 17 August 2009 - 05:27 PM
HSC is a proprietary formulation of naturally secreted embryonic proteins, growth factors and contains the first naturally stabilized, bioactive solution of Wnt proteins and their cofactors, which have been implicated in the induction of new hair follicle formation and growth.
The five-month double-blind, placebo-controlled clinical trial was focused on evaluation of safety in the clinical application of Histogen's Hair Stimulating Complex (HSC), formerly known as ReGenica. The 24 subject clinical trial was designed to examine the safety and efficacy of a single injection of HSC alone, as well as in combination with three different perturbation methods. Quantitative analysis of clinical macrophotography and subject biopsies were utilized to evaluate treatment safety and efficacy.
84.6% of the patients receiving one injection of Histogen's serum-free HSC showed an increase in terminal hair 12 weeks post-injection, with a statistically significant (p<0.05) increase in the number of terminal hairs, cumulative hair thickness density and hair thickness mean. Perturbation did not enhance the results seen with HSC. There were no adverse reactions seen in any of the treated 24 patients at baseline, 12 weeks, or the 22 week endpoint.
Posted 21 August 2009 - 06:22 PM
Stem cell growth factors used to regrow hair.
HSC is a proprietary formulation of naturally secreted embryonic proteins, growth factors and contains the first naturally stabilized, bioactive solution of Wnt proteins and their cofactors, which have been implicated in the induction of new hair follicle formation and growth.
The five-month double-blind, placebo-controlled clinical trial was focused on evaluation of safety in the clinical application of Histogen's Hair Stimulating Complex (HSC), formerly known as ReGenica. The 24 subject clinical trial was designed to examine the safety and efficacy of a single injection of HSC alone, as well as in combination with three different perturbation methods. Quantitative analysis of clinical macrophotography and subject biopsies were utilized to evaluate treatment safety and efficacy.
84.6% of the patients receiving one injection of Histogen's serum-free HSC showed an increase in terminal hair 12 weeks post-injection, with a statistically significant (p<0.05) increase in the number of terminal hairs, cumulative hair thickness density and hair thickness mean. Perturbation did not enhance the results seen with HSC. There were no adverse reactions seen in any of the treated 24 patients at baseline, 12 weeks, or the 22 week endpoint.
More valuable research that could eventually be applied to aging.
Edited by Ghostrider, 21 August 2009 - 06:24 PM.
Posted 10 December 2012 - 08:13 PM
In the new study, scientists from the U-M Department of Dermatology injected the skin of 21 volunteers in their 80s with a filler often used cosmetically to reduce facial wrinkles. The filler bolsters the ECM, filling in the spaces left by aging.
The researchers did not receive funding from the product's manufacturer, nor did they get input on the design or results from the company. Rather, they were using the product as a way to increase the mechanical forces within the volunteers' skin.
They also didn't focus on the face, where skin takes a beating over a lifetime of exposure to ultraviolet light and other insults that break down collagen. Instead, they focused on skin that had almost never seen the light of day -- the buttocks.
The result: over three months, the fibroblasts began expressing collagen-related genes, producing more collagen, and connecting better to the ECM. The entire layer of skin grew thicker, and more blood vessels, which nourished the cells were seen.
"Fragmentation of the extracellular matrix plays an important role in skin aging, but by altering the matrix using an external filler and increasing the internal pressure, we've shown that we can essentially trigger a signal for cells to wake up," says Gary Fisher, Ph.D., the Harry Helfman Professor of Molecular Dermatology and senior author of the new study, published in the Journal of Investigative Dermatology.
Posted 11 December 2012 - 12:13 PM
The visible signs of skin aging are reflected by a similar loss of elasticity and function in important tissues inside the body, driven by declining function in stem cells that support these tissues, a steep growth in the number of senescent cells that hamper maintenance of tissue integrity, the accumulation of AGEs - largely glucosepane - and the other mechanisms that cause aging.
These root causes must be dealt with, but comparatively few scientists are trying to tackle them directly. The more usual research focuses on ways to try to patch over consequences by making use of other mechanisms - somewhat akin to trying to deal with a broken dam by bailing rather than fixing the holes. Here researchers manage to reverse a fraction of the effects of skin aging:
[The] extracellular matrix, or ECM, acts like the scaffold that skin cells roost in. It's made of tiny fibrils of collagen, produced by the cells (fibroblasts). Over time, as skin ages, the ECM becomes fragmented, which causes cells to lose their connections to that scaffold - and the lack of support accelerates their decline further. The same thing may happen in other types of tissue.[Scientists] injected the skin of 21 volunteers in their 80s with a filler often used cosmetically to reduce facial wrinkles. The filler bolsters the ECM, filling in the spaces left by aging. The researchers did not receive funding from the product's manufacturer, nor did they get input on the design or results from the company. Rather, they were using the product as a way to increase the mechanical forces within the volunteers' skin. The result: over three months, the fibroblasts began expressing collagen-related genes, producing more collagen, and connecting better to the ECM. The entire layer of skin grew thicker, and more blood vessels, which nourished the cells were seen.
"Fragmentation of the extracellular matrix plays an important role in skin aging, but by altering the matrix using an external filler and increasing the internal pressure, we've shown that we can essentially trigger a signal for cells to wake up. This shows that skin cells in elderly people have the capacity to respond robustly in a very positive way to alterations in the mechanical property of their environment. We still need to know more about how cells sense their environment, but in general it appears we have made a real difference in the structural integrity of skin."
Link: http://www.scienceda...21210101351.htm
Posted 13 December 2012 - 05:48 PM
Posted 19 May 2013 - 06:11 PM
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