Warning: Urine mentioned. Hopefully I'm not being too gross / TMI!
I've been taking Piracetam for about 18 months now, and only recently noticed that when I take it I tend to use the bathroom far less. Overall I feel great and I had a complete blood test about a month ago (checked everything from hemoglobin to thyroid to white blood cells). My results were perfectly normal and indicated that I was extremely healthy.
In addition to about 1200 mg piracetam per day, I also take a multivitamin, a choline supplement, fish oil, grape seed extract, Ritalin (for ADHD) and oral contraceptives. I started noticing the water retention thing about 2 months ago - my whole life I've had a rather overactive bladder (no pathology was found for this - I was just told it was small bladder + anxiety). It's kind of nice to not be running to the bathroom so much, truthfully, but I have not been able to find ANYTHING in my Web searches on piracetam indicating this substance has an effect on fluid metabolism. I tried eliminating every other supplement or medication I take, one at a time, and piracetam is the ONLY thing that affects how often I have to pee. I'm just wondering if this substance has ever been used to treat overactive bladder, because it seems to be doing that quite well for me.
I've also noticed that my metabolism of B-vitamins seems to have been altered in the past few months. I used to get the bright yellow pee effect from taking large amounts of riboflavin, only this hasn't been happening recently. I'm not bleeding or anything; I just have a very normal color all the time. I'm just hoping that whatever effects I'm seeing are positive and not the sign of early kidney failure or something!
Any info / research on piracetam's effects on kidney / water balance?