Posted 11 May 2005 - 06:23 AM
A raw preview section from Cognitive Awareness
By LifeMirage
-Piracetam-
Piracetam (2-oxo-Pyrrolidine Acetamide) is a derivative of the neurotransmitter GABA (Gamma Amino Butyric Acid).
Interestingly it is chemically related to the amino acid Pyroglutamic Acid (Pyrrolidine Carboxylic acid), which occurs in cerebrospinal fluid and plays an important role in cognitive functioning.
-Biochemical Effects-
-Enhances Brain Metabolism (By increasing Glucose Utilization, Blood & Oxygen Flow) [Boosts mental energy & cerebral circulation].
-Increases Cerebral Phospholipids & Cellular Membrane Fluidity (By interacting with the polar head moieties of the phospholipid bilayer) [Supports healthy neuron communication & structure].
-Supports Cognitive Receptors (By amplifying the density of the Muscarinic Cholinergic [Frontal Cortex, Striatum, & Hippocampus], NMDA (N-Methyl-D-Aspartate) [Hippocampus], & AMPA (Alpha-amino-3-hydroxy-5-Methyl-4-isoxazole-Propionic Acid) [Cerebral Cortex] Receptors) [Strengthens neurotransmitter receptors involved in memory and neuroprotection].
-Stimulates the Corpus Callosum, an area of the brain that controls communication between the left and right hemispheres (Increases communication between both hemispheres) [Involved in speech and creative thinking].
- Stimulates the Locus Coeruleus, (specialized neurons) [Involved in information processing, attention, cortical/behavioral arousal, learning and memory]
-Inhibits Platelet Aggregation (By increasing Red-White blood cells & Platelet deformability, inhibiting thromboxane A2 synthetase or antagonism of thromboxane A2, reducing von Willebrand's factor & fibrinogen levels) [Reduces abnormal blood clots].
-Decreases EEG complexity (Increases cooperatively of brain functional processing) [Positively effects Neuro-Electrical Functioning].
-Has a significant antioxidant effect.
-Dose-
4.8-9.6 Grams daily. Some studies have used up to 45 grams daily.