PLEASE DO NOT TAKE NMDA AS A NOOTROPIC. NMDA is a known neurotoxin. Tonically activating NMDA receptors will create so many problems in the brain. Phasic activation of these receptors, at least the synaptic population, is what is responsible for LTP. Tonic activation will disrupt this. Taking NMDA will also mimic excitotoxicity and LTD, and could trigger seizures and neurodegeneration, or at the very least make you anxious and depressed. DO NOT, under ANY circumstances, INGEST NMDA FOR ANY REASON. NMDA is used merely as a research tool to study ion channel dynamics. Read some studies about what happens when rats were administered NMDA. If you want to enhance NMDA function there's plenty of nootropics to do so, such as piracetam, which increases several NMDA receptor subunits in specific, beneficial areas of the brain, or even more obscure ones like D-cycloserine, a much stronger drug and PAM of the NMDA receptor with quite a few side effects. Hell, you could even ingest glycine or d-serine or both, or more preferably FGL, just NOT NMDA. Please.
Edited by Targz, 25 July 2020 - 09:10 AM.