Flavonoids are a confusing subject. They are a "health fad" and people write about the benefits of flavonoids fruits and vegetables but their opinions are wildly at odds with each other.
Consider this: the below article is about how flavonoids can help block prostate disease/cancer because they are "estrogenic":
http://onlinelibrary...99.00270.x/full
Recently, several commonly occurring plant flavonoids have been shown to possess weak oestrogenic activity [ 12]. In particular, apigenin and kaempferol, both of which are oestrogenic, are regarded as two of the major flavonoids
Then you look up these flavanols and find out they're actually aromatase-inhibitors that boost testosterone which would be bad for prostate cancer. So which side claims that propaganda? The "breast-cancer" side, the bodybuilders, and those who want to increase their testosterone:
http://appliedergoge...e-you-star.html
"Bodybuilders would find apigenin useful because it's a natural aromatase inhibitor."
http://www.ironmagaz...sterone-levels/
"Apigenin – Everyday vegetables such as celery, onions and parsley contain testosterone-enhancing substances that, as we age, prevent our testosterone production from declining. Researchers at Texas Tech University discovered this. In the Journal of Nutritional Biochemistry they describe the experiments they did with apigenin, a promising testosterone booster, that’s found in high quantities in parsley"
https://www.ncbi.nlm...les/PMC2939222/
the present study demonstrates that apigenin is able to enhance StAR gene expression and steroid hormone production in mouse Leydig cells
Had enough? Now just for kicks, let's go back to the Prostate-Cancer side that loves flavonoids for slashing testosterone, reducing AR activity, and improving estrogen.
https://www.research...prostate_cancer
Four main flavonols - quercetin, myricetin, kaempferol, and fisetin - have been demonstrated in laboratory studies to have chemopreventive action in both castrate-resistant and castrate-sensitive PCa models. Mechanisms of flavonol action on the AR axis in PCa have been proposed to be inhibition of the 5α-reductase enzymes, direct androgen competition, suppression of the AR complex
Anti-androgenic effects of flavonols in prostate cancer (PDF Download Available). Available from: https://www.research...prostate_cancer [accessed Sep 7, 2017].
It's really quite amazing. When it comes to both life and science, there are competing factions and each will claim a health fad as its own, never mind the obvious absurdity of opposing claims.
It's like phytoestrogens. 50% of studies, articles and opinions will claim "phytoestrogens are estrogenic" and "contribute to estrogen dominance," the other 50%will claim "no no they are anti-estrogenic, because they actually COMPETE with estrogen, so they boost testosterone."
I've come to the conclusion that there are limits to science, or at least in how we use science.
Edited by ukw, 07 September 2017 - 11:21 PM.