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Fight Aging News
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Relationships Between Socioeconomic Status, Life Expectancy, and Epigenetic Age
As yet the life sciences have provided no way to...
Yesterday, 06:18 PM Read Full Story -
Naked Mole Rats Exhibit a Consistently Low Resting Metabolic Rate with Aging
Across mammalian species, resting metabolic rate...
Yesterday, 10:28 AM Read Full Story -
Thrombospondin-1 Secreted by Senescent Cells Impairs Bone Regeneration
Thrombospondin-1 is a component of the senescence...
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The Bidirectional Relationship Between the Burden of Cellular Senescence and Immune Aging
A cell becomes senescent given sufficient stress,...
Jun 16 2026 06:24 PM Read Full Story -
Late-Life Gene Therapy Boosts Lifespan in Mice by 20%
In a new study, muscle-targeted viral-vector-base...
Jun 16 2026 04:24 PM Read Full Story -
A Liver Aging Clock Predicts All Cause Mortality
Machine learning approaches can be used to create...
Jun 16 2026 10:22 AM Read Full Story
1
Metformin - a geroprotector?
May 19 2017 07:09 PM |
s123
in Articles
Sven Bulterijs first discussed the potential utility of anti-diabetic substance metformin six years ago on LongeCity. Now Sven returns to the topic with a comprehensive and thoughtful discussion of the recent findings and further background information ⇒ read the article in "Sven's Science Corner" blog
1 Comments
Here is an interesting study about using leucine with a reduced dose of metformin.
Ok it's a mouse study but I also saw a human study showing the same thing. I think
they were finding about 400mg of leucine and 125 mg metformin 3 times a day was
as effective as 500mg metformin 3 times a day for lowering blood sugar.
https://www.ncbi.nlm...pubmed/25858853