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George Church on Building “Scientific Superintelligence”
George Church, a Harvard professor and a famed ge...
Today, 05:00 PM Read Full Story -
Degree of Frailty Predicts Risk of Near Future Mortality
Frailty is a state of inflammation, physical weak...
Today, 11:27 AM Read Full Story -
Testing a Gain of Function Mutation in Insulin Receptor and IGF-1 Receptor in Mice
Loss of function mutations in insulin signaling h...
Today, 11:07 AM Read Full Story -
Injected Oxytocin Slows Cognitive Decline in Aged Mice
Circulating oxytocin levels are known to decline...
Yesterday, 07:22 PM Read Full Story -
How Senescent Cells Encourage Melanoma Growth
Researchers publishing in Aging Cell have documen...
Yesterday, 06:04 PM Read Full Story -
Mixed Results in a Meta-Analysis of Epigenetic Clocks and Frailty
Epigenetic clocks have existed for long enough fo...
Yesterday, 11:22 AM Read Full Story
Metformin - a geroprotector?
May 19 2017 07:09 PM |
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Sven Bulterijs first discussed the potential utility of anti-diabetic substance metformin six years ago on LongeCity. Now Sven returns to the topic with a comprehensive and thoughtful discussion of the recent findings and further background information ⇒ read the article in "Sven's Science Corner" blog















1 Comments
Here is an interesting study about using leucine with a reduced dose of metformin.
Ok it's a mouse study but I also saw a human study showing the same thing. I think
they were finding about 400mg of leucine and 125 mg metformin 3 times a day was
as effective as 500mg metformin 3 times a day for lowering blood sugar.
https://www.ncbi.nlm...pubmed/25858853