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Impairment of Glymphatic Cerebrospinal Fluid Drainage is a Feature of Cerebral Small Vessel Disease
The glymphatic system parallels blood vessels whe...
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A Year of Rejuvenation Research and Journalism
Happy holidays! Winter is in full swing for those...
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Long Term Treatment with Mesenchymal Stem Cell Extracellular Vesicles Improves Cognitive Function in Rhesus Monkeys
Much of the benefit of stem cell therapies result...
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Overexpressing TREX1 in Macrophages Reduces Injury Following Heart Attack
Researchers here describe an indirect method of i...
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Declining Chaperone Mediated Autophagy in the Aging of Muscle Tissue
A number of distinct cellular processes are label...
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Human Umbilical Cord Blood Metabolites Lengthen Worms’ Lives
Comparison of human umbilical cord blood with adu...
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Metformin - a geroprotector?
May 19 2017 07:09 PM |
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Sven Bulterijs first discussed the potential utility of anti-diabetic substance metformin six years ago on LongeCity. Now Sven returns to the topic with a comprehensive and thoughtful discussion of the recent findings and further background information ⇒ read the article in "Sven's Science Corner" blog















1 Comments
Here is an interesting study about using leucine with a reduced dose of metformin.
Ok it's a mouse study but I also saw a human study showing the same thing. I think
they were finding about 400mg of leucine and 125 mg metformin 3 times a day was
as effective as 500mg metformin 3 times a day for lowering blood sugar.
https://www.ncbi.nlm...pubmed/25858853