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Fight Aging News
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Position Effect Variegation as a Way to Visualize Age-Related Structural Change of Nuclear DNA
Nuclear DNA is surrounded by transcriptional mach...
Yesterday, 07:22 PM Read Full Story -
Creating CAR-T Cells Using Current Alzheimer’s Antibodies
A team of researchers has biologically engineered...
Yesterday, 05:23 PM Read Full Story -
DNA Methylation is Altered with Advancing Age
The addition and removal of methyl groups from sp...
Yesterday, 11:22 AM Read Full Story -
Reviewing mTOR Inhibition as a Mechanism to Slow Aging
Rapamycin is the most well studied of the mTOR in...
Yesterday, 11:11 AM Read Full Story -
mTOR Inhibitors Reduce DNA Damage and Consequent Cellular Senescence in Immune Cells
Rapamycin and other mTOR inhibitors mimic some of...
Feb 11 2026 07:02 PM Read Full Story -
Young Microbes Rejuvenate Intestinal Function in Mice
Transferring microbiota from young to aged mice h...
Feb 11 2026 04:57 PM Read Full Story
1
Metformin - a geroprotector?
May 19 2017 07:09 PM |
s123
in Articles
Sven Bulterijs first discussed the potential utility of anti-diabetic substance metformin six years ago on LongeCity. Now Sven returns to the topic with a comprehensive and thoughtful discussion of the recent findings and further background information ⇒ read the article in "Sven's Science Corner" blog
1 Comments
Here is an interesting study about using leucine with a reduced dose of metformin.
Ok it's a mouse study but I also saw a human study showing the same thing. I think
they were finding about 400mg of leucine and 125 mg metformin 3 times a day was
as effective as 500mg metformin 3 times a day for lowering blood sugar.
https://www.ncbi.nlm...pubmed/25858853