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Fight Aging News
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Fight Aging! Newsletter, July 7th 2025
Fight Aging! publishes news and commentary releva...
Today, 10:50 AM Read Full Story -
ALDH1A2 Overexpression Enables Ear Tissue Regeneration in Mice
In today's open access paper, researchers argue t...
Jul 04 2025 06:43 PM Read Full Story -
Fixing Sugar Metabolism Shows Promise Against Dementia
Scientists have shown that aberrant metabolism of...
Jul 04 2025 04:00 PM Read Full Story -
Reducing Microglial Senescence Slows Pathology in an Alzheimer's Disease Mouse Model
Microglia are innate immune cells of the brain, s...
Jul 04 2025 10:22 AM Read Full Story -
Long Term Physical Activity Correlates with Slowed Cognitive Decline
A mountain of human epidemiological data demonstr...
Jul 04 2025 10:11 AM Read Full Story -
An APOE3 Mutation Inhibits cGAS-STING Signaling to Reduce Inflammation in the Aging Brain
Variants of the APOE gene (the most common labele...
Jul 03 2025 06:26 PM Read Full Story

Metformin - a geroprotector?
May 19 2017 07:09 PM |
s123
in Articles

Sven Bulterijs first discussed the potential utility of anti-diabetic substance metformin six years ago on LongeCity. Now Sven returns to the topic with a comprehensive and thoughtful discussion of the recent findings and further background information ⇒ read the article in "Sven's Science Corner" blog
1 Comments
Here is an interesting study about using leucine with a reduced dose of metformin.
Ok it's a mouse study but I also saw a human study showing the same thing. I think
they were finding about 400mg of leucine and 125 mg metformin 3 times a day was
as effective as 500mg metformin 3 times a day for lowering blood sugar.
https://www.ncbi.nlm...pubmed/25858853