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Fight Aging News
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Epoxy-oxylipins as a Potential Means to Reduce Chronic Inflammation
Chronic inflammation is a major component of dege...
Yesterday, 07:01 PM Read Full Story -
Exercise Variety Is Associated With Lower Mortality Risk
A new study links exercise variety, defined as re...
Yesterday, 05:12 PM Read Full Story -
Reduced Mechanical Stimulation in Aged Bone Marrow Contributes to Cell Dysfunction
Cells react to physical forces placed upon them,...
Yesterday, 11:22 AM Read Full Story -
TNFα Contributes to Age-Related Liver and Intestinal Barrier Dysfunction
A sizable fraction of degenerative aging involves...
Yesterday, 11:11 AM Read Full Story -
Towards Small Molecule Reprogramming as a Basis for Rejuvenation Therapies
Exposing cells to the Yamanaka transcription fact...
Jan 22 2026 07:22 PM Read Full Story -
How Senescent Astrocytes Don’t Support Neurons
Resesarchers have found that thrombospondin-1 (TS...
Jan 22 2026 05:04 PM Read Full Story
1
Metformin - a geroprotector?
May 19 2017 07:09 PM |
s123
in Articles
Sven Bulterijs first discussed the potential utility of anti-diabetic substance metformin six years ago on LongeCity. Now Sven returns to the topic with a comprehensive and thoughtful discussion of the recent findings and further background information ⇒ read the article in "Sven's Science Corner" blog
1 Comments
Here is an interesting study about using leucine with a reduced dose of metformin.
Ok it's a mouse study but I also saw a human study showing the same thing. I think
they were finding about 400mg of leucine and 125 mg metformin 3 times a day was
as effective as 500mg metformin 3 times a day for lowering blood sugar.
https://www.ncbi.nlm...pubmed/25858853