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Fight Aging News
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Delving into the Dysfunction of Aging Neurons Involved in Impairment of Spatial Memory
There are many layers to aging research. There is...
Yesterday, 05:06 PM Read Full Story -
Nanoparticles Potently Reverse Alzheimer’s in Mice
Scientists have created polymersomes, a type of n...
Yesterday, 04:00 PM Read Full Story -
NUS Medicine Launches New Clinical Trial Centre
Spanning 350 square metres, the new Centre brings...
Yesterday, 12:15 PM Read Full Story -
PP2A-B55α as a Target to Improve Mitochondrial Function
Every cell contains hundreds of mitochondria, the...
Yesterday, 10:22 AM Read Full Story -
FDA Approval for Mitochondrial Therapeutic Elamipretide, Formerly SS-31
Elamipretide, originally known as SS-31, is a mit...
Yesterday, 10:11 AM Read Full Story -
Loss of Coordination of Gene Expression as a Biomarker of Aging
A number of lines of research indicate that coord...
Oct 09 2025 05:21 PM Read Full Story

Metformin - a geroprotector?
May 19 2017 07:09 PM |
s123
in Articles

Sven Bulterijs first discussed the potential utility of anti-diabetic substance metformin six years ago on LongeCity. Now Sven returns to the topic with a comprehensive and thoughtful discussion of the recent findings and further background information ⇒ read the article in "Sven's Science Corner" blog
1 Comments
Here is an interesting study about using leucine with a reduced dose of metformin.
Ok it's a mouse study but I also saw a human study showing the same thing. I think
they were finding about 400mg of leucine and 125 mg metformin 3 times a day was
as effective as 500mg metformin 3 times a day for lowering blood sugar.
https://www.ncbi.nlm...pubmed/25858853