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Fight Aging News
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A Review of Differences Identified in Gut Microbiome Composition Between Young, Old, and Long-Lived Individuals
The gut microbiome changes with age in ways that...
Yesterday, 06:16 PM Read Full Story -
Low-Fat Vegan Diet Shows Benefits in Type 2 Diabetes
A human trial found that even without caloric res...
Yesterday, 04:21 PM Read Full Story -
Second Century Foundation Launches to Advocate for Longevity Research
It is always good to see a diversification in non...
Yesterday, 10:22 AM Read Full Story -
A History of Research into Cellular Senescence
Cells become senescent in response to various for...
Yesterday, 10:11 AM Read Full Story -
An Anti-Senescence Gene May Fight Spinal Disc Deterioration
In Aging Cell, a team of researchers has describe...
Oct 12 2026 08:16 PM Read Full Story -
Age-Related Decline in Chaperone-Mediated Autophagy Impairs Clearance of Senescence Cells
Cells become senescent in response to stress and...
Oct 12 2026 06:35 PM Read Full Story
1
Metformin - a geroprotector?
May 19 2017 07:09 PM |
s123
in Articles
Sven Bulterijs first discussed the potential utility of anti-diabetic substance metformin six years ago on LongeCity. Now Sven returns to the topic with a comprehensive and thoughtful discussion of the recent findings and further background information ⇒ read the article in "Sven's Science Corner" blog
1 Comments
Here is an interesting study about using leucine with a reduced dose of metformin.
Ok it's a mouse study but I also saw a human study showing the same thing. I think
they were finding about 400mg of leucine and 125 mg metformin 3 times a day was
as effective as 500mg metformin 3 times a day for lowering blood sugar.
https://www.ncbi.nlm...pubmed/25858853