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              Advocacy & Research for Unlimited Lifespans

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  • Submitted: Aug 20 2017 10:21 PM
  • Date Updated: Aug 21 2017 12:34 AM
  • Views: 5607

Stength, Endurance, and Vitality: An Exercise-Memetic and Synergism Stack

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cordyceps sinensis fermented mycelium (cs-4 0.3% adenosine)) cordyceps militaris fruiting bodies (0.3% cordycepin) ashwagandha extract (ksm-66) ginger extract (5% gingerol)


This stack is designed for general health and well-being, with special attention to increasing aerobic exercise capacity, muscular strength, respiratory function, testosterone, libido, and mitochondrial function/ATP levels. It is simple, with only 4 components, yet very effective from my personal experience.


Cordyceps has been written of and revered since the Tang Dynasty (620 AD). Wild cordyceps is worth more than its weight in gold, and as a result, is prohibitively expensive for the vast majority of consumers. By combining lab-grown C.Sinensis CS-4 Mycelium with lab-grown C.Militaris fruiting body powder, one can achieve a ratio of active components (adenosine, cordycepin, polysaccharides) that is very close to what is found in wild, naturally grown cordyceps. Cordyceps has numerous studies supporting it's use as an effective exercise memetic, while also having potential to mediate some of the negative effects of aging and potentially increase lifespan.

Cordyceps sinensis promotes exercise endurance capacity of rats by activating skeletal muscle metabolic regulators.
RESULTS: Both CS supplementation and supplementation concurrent with exercise improved exercise endurance by 1.79- (P<0.05) and 2.9-fold (P<0.01) respectively as compared to placebo rats.
Antiaging effect of Cordyceps sinensis extract
In vivo and in vitro stimulatory effects of Cordyceps sinensis on testosterone production in mouse Leydig cells
Protective Effects on Mitochondria and Anti-Aging Activity of Polysaccharides from Cultivated Fruiting Bodies of Cordyceps militaris
Cordyceps sinensis CS-4 restores aging-associated changes in gene expression and extends lifespan in normal aged mice


Ashwaganda is another traditional adaptogen with a large body of scientific research supporting its purported effects. KSM-66 (standardized to 5% withanolides) is a component of this stack because it has been shown in published research to improve cardiorespiratory endurance, physical strength, testosterone levels, and sexual function.

Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial:

Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults
Clinical Evaluation of the Spermatogenic Activity of the Root Extract of Ashwagandha (Withania somnifera) in Oligospermic Males: A Pilot Study

Body Weight Management in Adults Under Chronic Stress Through Treatment With Ashwagandha Root Extract: A Double-Blind, Randomized, Placebo-Controlled Trial

Ginger, for the promotion of testosterone, appetite, and management of excess inflammation. (Also effective for rhintis)

Ginger (Zingiber officinale) Reduces Muscle Pain Caused by Eccentric Exercise
The effect of Ginger on semen parameters and serum FSH, LH & testosterone of infertile men.

Effects of Zingiber Officinale on Reproductive Functions in the Male Rat

Ingredient Dosage Frequency Administration
Cordyceps Sinensis Fermented Mycelium (CS-4, 0.3% adenosine)) 3.5 gram Daily To be taken in the morning or post-meal, preferably at least 1-2 hours before exercise.
Cordyceps Militaris Fruiting Bodies (0.3% cordycepin) 2 gram Daily To be taken in the morning or post-meal, preferably at least 1-2 hours before exercise.
Ashwagandha Extract (KSM-66) 300 mg twice daily To be taken post-meal, twice daily.
Ginger Extract (5% gingerol) 500 mg twice daily To be taken with meals.

This is the basic framework (exercise-capacity promoting portion) of a more complete stack that I take on a daily basis.

Additional supplements I take per day are:

  • Japanese Sencha - 10 to 15 grams per day, steeped in kyusu.
  • Spirulina - 3 to 6 grams
  • Vitamin K (menaQ7) - 90 to 180mcg
  • Vitamin D - 1000 to 2000 iu
  • Aged Garlic Extract (Kyolic) - 1800 mg divided into 2 doses
  • Magnesium Glycinate - 400mg before bed
  • Prebiotic formulation (composed of 4 tbsp high-maize resistant starch, 2 tbsp ground flax, bilberry/blueberry extract for gut microbiota modulation).