ImmInst Active Topics Last Updated: 20 May 2025 - 03:05 AM

Over the last 8 YEARS I've tried to get my hands on E. coli Nissle 1917 (MUTAFLOR) for its benefits on autoimmunity/HPA axis/gut issues, etc.

But the 4x I bought it, it was lost by the ¨#%&@¨$# Brazilian Mail service and arrived WAY too late, all bacteria as dead as nails the four times. (It's absurdly expensive by BR standards - and it must be kept refrigerated, so time's ticking as soon as it's sent).


 BACKGROUND: It's basically a supersoldier bacterial strain of (very) friendly E. coli that hunts down and destroys mercilessly a host of dysbiotic microbes, leading to hundreds of popular reports of complete remissions of dozens of types of autoimmune conditions, gut issues, skin conditions, and whatnot. 

 

Take a look at this study if you will: https://pmc.ncbi.nlm.nih.gov/articles/PMC5603654/ (Oral Administration of the Probiotic Strain Escherichia coli Nissle 1917 Reduces Susceptibility to Neuroinflammation and Repairs Experimental Autoimmune Encephalomyelitis-Induced Intestinal Barrier Dysfunction). 

There are dozens like it.

 

 

 RISE TO FAME: It's (in)famous for having been taken out of a soldier's arse in 1917 for having survived the trenches while everyone else died horribly of dysentery and also for having saved the life (or dearly improved the health) of Hitler as Dr. Morel, his personal physician, prescribed it to him in 1936.

 

 WHERE IT'S SOLD: AFAIK it's sold in Australia, NZ, Germany and perhaps a few Nordic countries (not in Sweden where I got extended family...) and not in Brazil (where I reside) and most of EU countries or US/Canada; It's got a bad legal status in most countries as it's a strain of E. coli and, therefore, considered a disease-causing bacteria (nonsense - this strain is extremely well-studied and ABSURDLY healthy/friendly).

 

 GETTING MUTAFLOR: I'm open to ANY way of getting MUTAFLOR. ANY idea/gimmick/hack that HELPs ME put my hands on this (still alive) strain of E Coli is deeply appreciated.


 HELP?: If any guy/gal from the Longecity community would be willing to help me get it/send it to me/whatever in some way that it would reach me alive, I'd appreciate it DEARLY...! It's being sh*t to stand these life-wrecking symptoms of autoimmunity and it could make a huge POSITIVE difference in my life quality.

As I said, I reside in Brazil, Porto Alegre, state of Rio Grande do Sul.



 

From the MUTAFLOR website

( https://www.mutaflor.com/mutaflor-clinically-proven-efficacy/introduction-and-overview.html )
 

 

https://biostasis.substack.com/p/field-cryoprotection-available-for

 

 

Host:

 

Max More, Director of Communications, Biostasis Technologies

Guests:

 

Aschwin de Wolf, President & CEO, Biostasis Technologies.

Lauren Fosco, Chief Operating Officer, Biostasis Technologies. Director, Cryonics Institute.

Rudi Hoffman, Certified Financial Planner and leading insurance agent for cryonicists.
 

Suspended Animation Inc. (SA) has provided SST (standby, stabilization, and transport) to Cryonics Institute (CI) members for years. SST is a crucial part of the cryopreservation process. When a cryonics patient is not near the cryonics organization, there is an delay in getting them cryoprotected. Even with a blood washout before transport, ischemic injury will accumulate. By doing cryoprotection in the field – at the patient’s location – ischemic time can be greatly reduced, improving the quality of the cryopreservation.
 

Biostasis Technologies (BT) is not a cryonics service provider. BT offers help to all cryonics/biostasis organizations to improve protocols and advance research. This episode focuses on a new option for Cryonics Institute members.

In this discussion, you will learn answers to these questions:

• What is the difference between cryoprotection and cryopreservation?

• How is field cryoprotection (FCP) different from current CI/SA procedure?

• Why are FCP patients shipped on dry ice? Why dry ice rather than ice? Why dry ice rather than liquid nitrogen?

• Which cryoprotectant is used for FCP?

• Do other cryonics organizations offer whole-body FCP?

• What do you mean by true whole-body field cryoprotection?

• Why is this better than existing SA SST procedures?

• How do CI and SA cooperate to deliver SST/FCP?

• Why are SST and FCP more expensive than CI membership itself?

• I am already an SA client. What do I need to do?

• How do I ensure that my funding allows for new future developments?

• What funding level is appropriate for potential FCP expansion outside of the US?

• How do I change amounts between beneficiaries in my existing policy?

• Can I pay for the FCP upgrade in cash?

• Where do the SST protocols originate and how are they monitored?

 

 

Hi everyone,

I've been reading Longecity for years, especially the tech and space discussions, and wanted to share a thought that often gets overlooked — the role of geospatial mapping technologies in both earthly and extraterrestrial exploration.

Today, GIS (Geographic Information Systems) has evolved far beyond traditional maps. It's now a crucial tool for visualizing how cities grow, how land is utilized, and how environments shift over time. These same technologies are becoming essential in simulating Martian surfaces and even mapping moons or exoplanets.

For instance, while working on regional mapping platforms for Pakistan, I’ve seen firsthand how interactive country-level maps can help visualize urban sprawl and infrastructure planning. On the historical side, projects that combine antique map overlays with modern GIS give us fascinating insights into how landscapes have evolved across centuries — a method that’s surprisingly relevant for planetary geology as well.

What fascinates me is how these earth-focused technologies are quietly laying the groundwork for future space colonization and resource mapping beyond our planet.

What’s your take?
Do you think GIS tools developed for urban planning and land visualization here on Earth will directly influence how we map and navigate space environments in the next decade?

Would love to hear your insights.

Greetings from Sydney

Hi,

I'm interested to find a product with the maximum dosage of Piracetam per tablet or injection (vial).

Does anyone know of any product?

Your decision to undergo cryopreservation reflects a long-term bet on science, technology, and human ingenuity. It’s a bold choice—and while it's speculative, it's not unreasonable to imagine that revival might someday be possible. But we should be honest: the barriers are immense, and a specific timeline is nearly impossible to predict with confidence.

Here’s a grounded breakdown:

Why It’s Not Entirely Unreasonable

1. Exponential Technology Growth: Medical and computational advancements have grown rapidly. Consider the pace of progress in genomics, brain-computer interfaces, synthetic biology, and now AI-accelerated science.

2. AI Acceleration: AI already helps design proteins (e.g., AlphaFold), simulate molecules, and model biological processes at previously impossible scales. Future AI might help decode and repair cryopreserved tissues or model a brain's structure from damaged or frozen matter.

3. Nanotechnology Potential: Eric Drexler and others have speculated that future nanomachines might one day repair cellular damage at a molecular level—exactly what’s needed for cryonics to work.

Why It’s Still a Huge Leap

1. No Known Successful Revival (Even of Simple Organisms): We haven’t yet revived a complex organism (like a mammal) from true cryopreservation, much less a human.

2. Structural Damage from Freezing: Even with vitrification (glass-like freezing), ice formation and fracturing cause damage that may be irreparable without future technology.

3. Information Theory of Death: If key neural structures are destroyed (even subtly), the continuity of identity might be lost, even if “you” are rebuilt.

4. Legal and Ethical Uncertainty: By the time revival is technologically possible, there may be complex issues surrounding identity, rights, and societal integration.

Speculative Timeline

This is where we must tread carefully. Based on current progress, a plausible "optimistic" window for solving cryonics revival might be:

• Not before 2100.

• Possibly 2150–2300, assuming breakthroughs in:

  • Advanced nanotechnology,

  • Full brain emulation (or equivalent),

  • Reversible cryopreservation of a mammalian brain (first milestone),

  • And continued AI acceleration.

Ray Kurzweil’s projections in The Singularity Is Near suggest that by 2045, we might see "superintelligence" capable of medical miracles—but even in that optimistic framework, full revival from cryopreservation is not a certainty.

Bottom Line

It’s not unreasonable to hope—but it’s crucial to recognize the leap of faith involved. Your bet is on several simultaneous revolutions: in medicine, AI, materials science, neuroscience, and ethics. If even a few go further than expected, your hope could become more than just science fiction.

Would you like a visual timeline or roadmap showing the milestones likely needed for revival to become feasible?

Hi,
My regimen is

GEROVITAL H3 Injections Zentiva - 3 vials Monday Wednesday Friday - 12 Injections/ month

Cerebrolysin 5ml - 2 vials Tuesday / Thursday

Memotal Zentiva - piracetam - 1 vial / week

Cebrium Ever Pharma - 2 tablets/ day

and the most important to boost all of these
CEBRAOPTIM - 3 caps daily

Myers cocktail PharmaLife Laboratories - 5 infusions × 20ml