ImmInst Active Topics Last Updated: 17 June 2025 - 01:25 AM

A decade ago, I started writing a story about a Biohacking cybercriminal named "Nero" who meets a beautiful Colombian woman, Astrid, and - against all odds - makes her his to lose because he is on the right Smart Drugs. But she has a devious twin sister who draws him into a web of intrigue with a sinister tech company mining human "pre-cognitive capital" to predict the future.

 

Since I started writing it, I've personally trailed over 200 different Smart Drugs and Nootropics, along with self-experimenting with a bunch of weird and wacky personal growth things. There are a million health/biohacking/self-help books - so I decided to write a novel instead (an edgy one).

Limitless meets Black Mirror meets American Psycho in "Hourglass" - my debut science fiction novel available now for your reading and listening pleasure as a digital book "Odyssey of the Mind" style audiobook.

• It's kind of a personal transformation guide masquerading as a novel - illustrating the application of some of the edgier Biohacks, lifehacks, and social dynamics hacks - but more sci-fi thriller novel than a self-help book!
• In the story, our protagonist must solve the greatest unsolved mystery in mathematics - the Goldbach Conjecture. To do so, I describe the ultimate Biohacking stack of Smart Drugs, Nootropics, peptides, brainpower-boosting tech, and flowstate induction tools that he uses to make a momentous historical breakthrough. If you faced a monumental brainpower challenge - that would define your life trajectory and change the world - and had a small fortune to invest in your Biohacking, THIS would be the stack to unleash unequaled brilliance.
• There's a drug, dubiously a Nootropic - something not well-known (even in these corners) that may make you rich. But it may turn you into a rapacious and voracious psychopathic capitalist. A couple of high-profile white-collar criminals have used it. I reveal it in this novel.
• Bodybuilding/Beauty biohacks - The protagonist, a computer geek, uses various hacks to transform himself into a dude studly enough to get an exquisite woman.
• Psychedelics - These have 'light' and very 'dark' sides - as you'll see in the story!
• Epigenetic identity re-programming - this is one of the most powerful mindset tools I've found in 14 years of self-experimentation.
• Mnemonic 'Memory Palaces' that make lust - not a master - but a tool for creativity and semantic smarts.
• Sex hacking - Tantra, sexual transmutation techniques, and herbal libido enhancers - all in the book. Yeah, this is a spicy one!
• Frame control, seduction dynamics, and other real-life "Jedi Mind Tricks."
• I'm spilling some metaphorical ink to ensure it's a funny book. I dare say it will make you laugh out loud at points!
• The book has over a hundred footnotes, giving you link rabbit holes and more information about the different Biohacks and lifehacks that drive the story forward.

Hourglass is around 370 pages and an 11-hour audiobook, but it is a thriller - almost every chapter ends with a cliffhanger that will keep you guessing - it won't take you three months to get through!

BEFORE YOU ASK: It's not on Amazon or Audible - I'm author-banned on Amazon.

Order Novel [Audiobook Included]

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https://www.globenewswire.com/news-release/2025/04/03/3055472/0/en/Best-SARMs-For-Cutting-Bulking-Muscle-Growth-2025-Top-Fat-Loss-Sarms-Stack-For-Sale-On-The-Market-CrazyBulk.html

 

https://www.globenewswire.com/news-release/2025/04/23/3066838/0/en/Sarms-Vs-Steroids-The-Best-Sarms-And-Legal-Steroids-For-Cutting-Bulking-And-Bodybuilding-In-2025-Tested-And-Rated-By-Crazy-Bulk.html

 

https://finance.yahoo.com/news/best-sarms-2025-strongest-sarms-180900375.html

 

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https://online.visual-paradigm.com/community/bookshelf/default-26xmuq2oe3

 

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https://knowt.com/note/62c74607-077a-4c17-a35a-691a2bf798e0/Are-Best-SARMs-Better-Than-Steroids-for-

 

https://nas.io/best-sarms-for-beginners/challenges/how-do-best-sarms-compare-for-cutting-vs-bulking

 

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https://www.globenewswire.com/news-release/2025/05/01/3072733/0/en/Best-SARMs-2025-Strongest-SARMs-for-Bulking-Cutting-Muscle-Growth-and-Strength-Are-SARMs-Legal-Or-Safe-Best-Sarm-for-Fat-Loss-CrazyBulk.html

 

https://www.globenewswire.com/news-release/2025/04/23/3066838/0/en/Sarms-Vs-Steroids-The-Best-Sarms-And-Legal-Steroids-For-Cutting-Bulking-And-Bodybuilding-In-2025-Tested-And-Rated-By-Crazy-Bulk.html

 

https://finance.yahoo.com/news/sarms-vs-steroids-best-sarms-193400525.html

 

https://dailyguardian.ca/sarms-vs-steroids-the-best-sarms-and-legal-steroids-for-cutting-bulking-and-bodybuilding-in-2025-tested-and-rated-by-crazy-bulk/

 

https://www.deccanherald.com/dhbrandpr-health/best-sarms-for-cutting-bulking-muscle-growth-2025-safest-fat-loss-sarm-stack-steroids-3369385

 

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https://www.globenewswire.com/news-release/2025/04/03/3055472/0/en/Best-SARMs-For-Cutting-Bulking-Muscle-Growth-2025-Top-Fat-Loss-Sarms-Stack-For-Sale-On-The-Market-CrazyBulk.html

 

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https://www.pnas.org/doi/10.1073/pnas.2416433122

 

Brain aging shows nonlinear transitions, suggesting a midlife “critical window” for metabolic intervention

 

Age-related cognitive decline is associated with metabolic, vascular, and inflammatory changes, making it challenging to distinguish primary causes from secondary (downstream) effects. This study demonstrates that brain aging follows a specific progression, with the first stage occurring in middle age and coinciding with increased insulin resistance. Moreover, we show that brain areas that age fastest are also those most vulnerable to neuronal insulin resistance. Importantly, we find that administering ketones, which can fuel neurons while bypassing insulin resistance, reverses brain aging effects. However, this intervention is only effective when provided early enough for neurons to remain viable. These findings contribute to our understanding of brain aging mechanisms and suggest neurometabolic strategies for targeted early intervention in preventing age-related cognitive decline.

Abstract
Understanding the key drivers of brain aging is essential for effective prevention and treatment of neurodegenerative diseases. Here, we integrate human brain and physiological data to investigate underlying mechanisms. Functional MRI analyses across four large datasets (totaling 19,300 participants) show that brain networks not only destabilize throughout the lifetime but do so along a nonlinear trajectory, with consistent temporal “landmarks” of brain aging starting in midlife (40s). Comparison of metabolic, vascular, and inflammatory biomarkers implicate dysregulated glucose homeostasis as the driver mechanism for these transitions. Correlation between the brain’s regionally heterogeneous patterns of aging and gene expression further supports these findings, selectively implicating GLUT4 (insulin-dependent glucose transporter) and APOE (lipid transport protein). Notably, MCT2 (a neuronal, but not glial, ketone transporter) emerges as a potential counteracting factor by facilitating neurons’ energy uptake independently of insulin. Consistent with these results, an interventional study of 101 participants shows that ketones exhibit robust effects in restabilizing brain networks, maximized from ages 40 to 60, suggesting a midlife “critical window” for early metabolic intervention.

 

 

 

One problem with this is that they used pure ( R )-3-hydroxybutyl-( R )-3-hydroxybutyrate monoester (ΔG ketone monoester, HVMN Inc., Miami, FL) dosed at 395 mg per kg of body weight and diluted with water (volume ratio 1:1.6).

 

This is important because if you tried to take that dose of any of the available Beta-Hydroxybutyrate (BHB) salts, it would result in a highly toxic if not fatal dose of potassium and possibly magnesium, and at least a very excessive dose of calcium or sodium. The monoester avoids this, but it's very very expensive (about $30 per dose from what I could find).

 

On the other hand, I found a Japanese supplier of the acid which may require refrigeration but has no metal in the compound. They sell only wholesale, so a group buy may be a possibility. It will still probably not be at all cheap.

 

Or we can always just do a keto diet.

 

 

I recently interviewed the founders of the Rejuvenation Science Institute in Brazil. This is a recent non-profit effort founded by Nicholas Chenovsky and Nina Torres-Zanvettor.

 

They are undertaking an ambitious effort to reproduce Dr. Harold Katcher's rejuvenation experiment in mice. Replication is VERY important and they are raising money to fund this effort. 

 

Listen to the podcast here: https://www.longecity.org/podcast/?name=2025-06-03_longecity_now_2025_rejuvenation_science_institute.mp3

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5. Ringer Solution IV

 

source: gerovitalcosmetic.com

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