Would anyone be interested in looking into a group buy for the novel Nootropic α5IA?
An inverse agonist selective for alpha5 subunit-containing GABAA receptors enhances cognition.
alpha5IA significantly enhanced performance in a rat hippocampal-dependent test of learning and memory, the delayed-matching-to-position version of the Morris water maze, with a minimum effective oral dose of 0.3 mg/kg, which corresponded to a BZ site occupancy of 25%.
An inverse agonist selective for alpha5 subunit-containing GABAA receptors improves encoding and recall but not consolidation in the Morris water maze. These data further highlight the cognition-enhancing properties of GABAA alpha5-selective inverse agonists and define the functional specificity of these effects in terms of encoding and recall processes in the Morris water maze. https://www.ncbi.nlm...pubmed/16633803
Edited by metabrain, 28 May 2018 - 08:53 PM.
