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              Advocacy & Research for Unlimited Lifespans


Brasky study - long term supplementation with Vitamins B6 and B12 significantly increase cancer risk in Men

b12 brasky cancer

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#1 kilgoretrout

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Posted 14 June 2018 - 06:18 PM

Anyone know of any rebuttals or responses or reports on this study that don't just presume it is correct because it is a published study?


Always suspicious of "Association" studies with no identified mechanism.


Do B vitamins increase the risk of getting cancer?
Recent evidence has linked B vitamins (specifically B6 and B12) to an increased risk of lung cancer in men, especially in smokers. Here, we analyze the study and interview the lead author, Dr. Theodore Brasky.





This page engages in some sceptical reporting;



Dr Ahmadi also raised methodological concerns, saying that “there are only two or three nominally significant” results for the “highest dose categories which suggest very few subjects contributed to the highlighted associations”.
And Professor Paul Pharoah, of Cambridge University, said the study’s “headline results” should be taken with a “pinch of salt”.
“The most likely explanation for those findings is statistical chance,” he said.
“The authors have investigated many sub-groups … and they have focused on the results that are most significant.
“Previous randomised controlled trials have found little evidence of association for supplementation of these vitamins on lung cancer risk.
“In summary, this in an intriguing finding, but it cannot be considered definitive.  While it is possible that the findings are real, the most likely explanation is statistical chance.”



























Edited by kilgoretrout, 14 June 2018 - 06:28 PM.

#2 Kalliste

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Posted 04 July 2018 - 07:43 AM

B-vitamins have come up in association with cancer risk many times, if coupled with smoking.


But as they mention, it might be a dosage problem. Imagine the conclusion of an Aspirin study were subjects took between 1-100 grams of aspirin...

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Also tagged with one or more of these keywords: b12, brasky, cancer

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