2 replies to this topic

[Philipp]

Hi all,

 

I've been asked by a friend about their 12 year old child who has leukemia, and whether C60 could help with that. In theory, certainly C60 helps with anything related to environmental burden, detoxifying the body, cellular boost and neutralizing free radicals. So it should make the body stronger regardless.

 

However, do you know of any specific reports, studies and/r anecdotal reports specifically in regards to leukemia and/or cancer in general, as well as kids?

 

Thank you for your input!

[Turnbuckle]

C60 has been studied re leukemia, and may have some directly toxic effects on cancer cells and some utility when used with other drugs, but does not appear to be a magic bullet. 

 

 

Abstract

Background

C60 fullerene-based nanoformulations are proposed to have a direct toxic effect on tumor cells. Previous investigations demonstrated that C60 fullerene used alone or being conjugated with chemotherapeutic agents possesses a potent anticancer activity. The main aim of this study was to investigate the effect of C60 fullerene and its nanocomplexes with anticancer drugs on human phagocyte metabolic profile in vitro.

 

Methods

Analysis of the metabolic profile of phagocytes exposed to C60 fullerene in vitro revealed augmented phagocytic activity and down-regulated reactive nitrogen species generation in these cells. Additionally, cytofluorimetric analysis showed that C60 fullerene can exert direct cytotoxic effect on normal and transformed phagocytes through the vigorous induction of intracellular reactive oxygen species generation.

 

Results

Cytotoxic action as well as the pro-oxidant effect of C60 fullerene was more pronounced toward malignant phagocytes. At the same time, C60 fullerenes have the ability to down-regulate the pro-oxidant effect of cisplatin on normal cells. These results indicate that C60 fullerenes may influence phagocyte metabolism and have both pro-oxidant and antioxidant properties.

https://www.ncbi.nlm...les/PMC6208740/

 

 

Edited by Turnbuckle, 08 February 2019 - 01:31 AM.

[Philipp]

Thank you!