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Creatine Protects Neurons - and What Else?

creatine cell protection

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4 replies to this topic

#1 manofsan

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Posted 14 March 2019 - 02:17 AM


Creatine is supposed to be neuroprotective - so it protects neurons - but what else does it protect?

 

What is the mechanism by which it provides neuroprotection? Does this mechanism also afford protection for other cell types?

 

Have there been any studies on the effect of Creatine on other types of cells? What have the results been?



#2 manofsan

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Posted 16 March 2019 - 01:36 AM

Since I take both Creatine and Fisetin, I'd like to know if the Creatine's protective qualities can oppose the Fisetin's senolytic qualities, thereby protecting some senescent cells from apoptosis?

 

Anyone have any opinions on this?


Edited by manofsan, 16 March 2019 - 01:38 AM.

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#3 Heyguy

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Posted 19 March 2019 - 02:12 PM

https://examine.com/...ments/creatine/

Edited by Heyguy, 19 March 2019 - 02:13 PM.

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#4 Daniel Cooper

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Posted 20 March 2019 - 02:36 PM

Since I take both Creatine and Fisetin, I'd like to know if the Creatine's protective qualities can oppose the Fisetin's senolytic qualities, thereby protecting some senescent cells from apoptosis?

 

Anyone have any opinions on this?

 

 

My opinion is that I'd have a washout period where I stopped all supplements before I did a round of any senolytic.  You aren't going to have any issues with temporarily discontinuing your supplement regime for a week or so and some of them may potentially interfere with the senolytic activity you're trying to promote.



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#5 manofsan

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Posted 21 March 2019 - 03:09 AM

My opinion is that I'd have a washout period where I stopped all supplements before I did a round of any senolytic.  You aren't going to have any issues with temporarily discontinuing your supplement regime for a week or so and some of them may potentially interfere with the senolytic activity you're trying to promote.

 

Hi, but Creatine could take up to a month to wash out of your system.

 

I do however wonder which metabolic pathways Creatine affects.







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