• Log in with Facebook Log in with Twitter Log In with Google      Sign In    
  • Create Account
  LongeCity
              Advocacy & Research for Unlimited Lifespans

Photo
- - - - -

a2a antagonist as safe-no tolerance stimulant

adenosine stimulant a2a tolerance

  • Please log in to reply
No replies to this topic
⌛⇒ support MITOMOUSE via LongeCity!

#1 Painkillerrr

  • Guest
  • 116 posts
  • 6
  • Location:Italy
  • NO

Posted 29 March 2019 - 12:05 PM


Hello, i have not menaged to find any strong stimulant without tolerance. the only good target that i have found is adenosine 2a.

 

a2a antagonists are being tested as new parkinson treatment [1] and pretty much any parkinson drugs is a possible stimulant for healthy (l-dopa, mao inhibitors ecc.)

 

caffeine is a a2a antagonist, but its short-term effect and lack of selectivity (a1 antagonism cause tolernace overtime [2]) makes it pretty much useless for me.

 

teacrine seemed good, but it has no real stimulation and ruins my sleep (max 4-5 h while i take it in the morning)

 

[1] https://www.ncbi.nlm...les/PMC2583202/

 

[2]https://www.scienced...014299900006828

 

studies: https://sci-hub.tw/1...1910-012-0279-2

 

is there someone who would like to do a small-group buy it buy any selective a2a antagonist??

 

the price should be low







Also tagged with one or more of these keywords: adenosine, stimulant, a2a, tolerance

0 user(s) are reading this topic

0 members, 0 guests, 0 anonymous users