http://news.bbc.co.u...lth/2856735.stmTuesday, 25 March, 2003, 14:35 GMT
Q&A: Mystery pneumoniaA lethal infection has prompted the World Health Organisation to issue a global alert to doctors and governments.
The respiratory illness has so far killed at least 18 people - and perhaps as more than 50 - and BBC News Online reports what is understood about it so far.
What do we know about the source of the infection? The first reports of an infection followed the death of a US businessman in Hong Kong.
The man had visited China and Vietnam - hospital staff there and in Hong Kong subsequently fell ill.
However, it now seems possible that he was not the source of the Hong Kong outbreak.
It is possible, though not confirmed, that the initial source of the infection was China, where an outbreak of respiratory illness in Guangdong province has killed 31 people.
What form does the illness take? Known symptoms of the infection are similar to those experienced by an influenza sufferer, including high fever, headache sore throat, and cough.
In some cases pneumonia has developed, with patients finding it very hard to breathe - some have required artificial ventilation in hospital.
In the absence of a better description, the World Health Organisation have termed it "Severe Acute Respiratory Syndrome" (SARS).
What is it, and how is the illness transmitted? Scientists now believe they have confirmed the culprit for the disease.
The scientists, from the US Centers for Disease Control, believe it is Corona virus.
This family of viruses is well known as a cause of the common cold.
This is possibly a new strain which has mutated to become more dangerous to humans.
Nothing is certain however - there is the chance that while this virus can be found in many people who have fallen ill, it is simply one factor in the illness, and the principal symptoms have been caused by another bug.
Initial reports suggest that the incubation period of the illness is less than seven days.
So far, there have been 487 cases outside China and 18 deaths.
Although not confirmed, it is likely that infection takes place through droplets of body fluids - produced by sneezing or coughing.
The illness has already reached North America and Europe because of the easy availability of air travel.
What can I do to protect myself? Not a great deal, should the illness become established in the UK.
Professor John Oxford, a virology expert from Queen Mary's College in London, told BBC News Online: "There's no much you can do to avoid this, unless you go and live as a hermit."
The Public Health Laboratory Service and Department of Health are not yet advising people not to travel to the Far East.
Professor Oxford added: "If I had a holiday in the Far East booked this week, I certainly wouldn't cancel it."
Some people in Hong Kong have taken to wearing face masks, but it is unclear exactly how much protection these would offer against viral particles.
The illness has been compared to the 1918 flu pandemic. Is this really the case? No. It's fair to say that the WHO was concerned about it, particularly as when it didn't yet know what it was.
The mortality rate for the illness is approximately 4% - higher than many respiratory infections.
However, the 1918 pandemic killed as many as 40 million, so this infection is not quite as serious yet.
What are governments and experts - and airlines - doing to stop it? The WHO global alert triggered responses from health experts in dozens of countries.
Doctors have been asked to look out for cases, particularly arising in patients who have recently returned from abroad, and notify public health services so that the spread of the illness can be monitored.
Airlines have been asked to look out for passengers who appear unwell while checking in.
They have also been advised to disinfect aircraft in a bid to stop its spread.
In hospitals, staff have been instructed to use "barrier nursing" to try to prevent more infections.
What advice does the UK government have for travellers? The Department of Health says travellers returning to the UK from any affected area since 23rd February should seek medical advice if they have suddenly developed a high fever, or one other symptom of pneumonia.
These include cough, sore throat or shortness of breath, or muscle aches.
At present, the government is not advising people to avoid travel to affected areas.