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Thoughts on treating MAOI insomnia with norepeniphrine antagonists (beta blockers)?

maoi norepeniphrine insomnia beta blocker moclobemide

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#1 Intropersona

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Posted 02 June 2019 - 08:07 AM


Maoi is regularly prescribed for depression and is a great motivation booster/nootropic IME.

 

Beta blockers (like clonidine) are regularly prescribed for sleep issues. - https://www.medicine...nax/article.htm

 

Reversible MAOI (like moclobemide) allow excess norepeniphrine to proliferate during sleeping hours thereby disrupting sleep.

 

My experience with clonidine on MAOI was horrible as the half life is FAR too long (12 hours) and led me to be fatigued for over 2 days with depressed respiration rate. More looking at something like pronalol (4hours) or Phentolamine (20mins).



#2 Diamondz

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Posted 17 June 2019 - 01:55 AM

You have a source for Moclobemide?



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Also tagged with one or more of these keywords: maoi, norepeniphrine, insomnia, beta blocker, moclobemide

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