Is anyone aware of any extra-virgin olive oil brands that are known to be particularly high in phenol content?
Br J Nutr. 2006 Apr;95(4):742-51.
Daily consumption of a high-phenol extra-virgin olive oil reduces
oxidative DNA damage in postmenopausal women.
Salvini S, Sera F, Caruso D, Giovannelli L, Visioli F, Saieva C, Masala
G, Ceroti M, Giovacchini V, Pitozzi V, Galli C, Romani A, Mulinacci N,
Bortolomeazzi R, Dolara P, Palli D.
Molecular and Nutritional Epidemiology Unit, Centro per lo Studio e la
Prevenzione Oncologica (CSPO), Scientific Institute of Tuscany,
Florence, Italy. ssalvini.....@cspo.it
Extra-virgin olive oils (EVOO), high in phenolic compounds with
antioxidant properties, could be partly responsible for the lower
mortality and incidence of cancer and CVD in the Mediterranean region.
The present study aims to measure oxidative DNA damage in healthy human
subjects consuming olive oils with different concentrations of natural
phenols. A randomised cross-over trial of high-phenol EVOO (high-EVOO;
592 mg total phenols/kg) v. low-phenol EVOO (low-EVOO; 147 mg/kg) was
conducted in ten postmenopausal women in Florence. Subjects were asked
to substitute all types of fat and oils habitually consumed with the
study oil (50 g/d) for 8 weeks in each period. Oxidative DNA damage was
measured by the comet assay in peripheral blood lymphocytes, collected
at each visit during the study period. Urine samples over 24 h were
collected to measure the excretion of the olive oil phenols. The
average of the four measurements of oxidative DNA damage during
treatment with high-EVOO was 30 % lower than the average during the
low-EVOO treatment (P=0.02). Urinary excretion of hydroxytyrosol and
its metabolite homovanillyl alcohol were significantly increased in
subjects consuming high-EVOO. Despite the small sample size, the
present study showed a reduction of DNA damage by consumption of an
EVOO rich in phenols, particularly hydroxytyrosol.
PMID: 16571154 [PubMed - in process]