3 replies to this topic

[hallucinogen]

Aight, I got a LOT:p of Piracetam and DMAE, and some Aniracetam, Idebenone and then some Alpha-GPC as a choline source (also some Pyroglutamic Acid - Is it even useful??? Or should I just throw it away...)

Then from herbal stuff, I got some Bacopa Monierri and Avena Sativa


Someone help me out with the best combination/dosages to take, for Pete's sake or make a reference to the relevant posts....pls

Edited by hallucinogen, 04 June 2006 - 05:45 AM.

[Ghostrider]

Aight, I got a LOT:p of Piracetam and DMAE, and some Aniracetam, Idebenone and then some Alpha-GPC as a choline source (also some Pyroglutamic Acid - Is it even useful??? Or should I just throw it away...)

Then from herbal stuff, I got some Bacopa Monierri  and Avena Sativa


Someone help me out, for Pete's sake or make a reference to the relevant posts....pls

Well, first of all, I don't have a Ph.D and my knowledge of medicine / biology could be better. But the general and best advise is to start at the smaller dosages and work up from there if needed. Regarding Piracetam, most people recommend starting out a 800 mg and taking twice a day. If you don't feel anything, try taking 1.6 grams twice a day. Still nothing, try 2.4 grams twice a day. But I don't think I would go much further beyond that. The stuff is essentially non-toxic with an extremely high LD50. Water is basically more lethal than Piracetam. Aniracetam, the same, but Aniracetam is reputed to be more potent compared to Piracetam so I would not go over two dosages of 1.6 grams per day. Alpha-GPC, I would recommend 300 mg if you are only taking 800 mg of Pir and 600 mg if you go beyond 1.6 grams of Pir per day. Taking DMAE along with the Alpha-GPC should allow you to use a slightly smaller dosage of Alpha-GPC. To be honest though, DMAE and Alpha-GPC did nothing noticable for me. For me I think the effects that I felt from Piracetam was mostly placebo. I am pretty sure I still feel its presence, but it is very subtle for me. I did feel Aniracetam, but only at 1.6 grams, which is somewhat high. I am getting Oxiracetam and will experiement with that as well. Generally though, be on the lookout for placebo. Then again, if (you can get the placebo effect && it is just as strong every time && the effect is just what you are looking for && there is no cheaper substitute) effect == perfect; else save your money.

Again, I am only relaying to you what I have heard from others. I am not a professional and I am learning myself.

[hallucinogen]

bump

[doug123]

bump

Dude, I check my email at least 10 times a day, and about half of those times I happen to have time to read this forum. If I answered every post I read, I would probably go more psycho than I already am. [ang]

Anyone interested in cognition enhancers should investigate and question the research supporting the use of compounds for which we have strong evidence of their efficacy in healthy subjects first rather than take the latest snake oil.

That said:

I take 750 mg Aniracetam twice a day; 1 gram American Lecithin 60% GPC twice a day as well -- both with meals.

I don't mess with Piracetam because the mg/kg is way too high...I take Oxiracetam 800mg twice a day though.

I don't mess with idebenone either because it might not be safe and the benefits (even in elderly subjects) are lackluster -- 2% increase? Not worth the risk -- especially considering it's a dietary supplement and the high price.

I take Bacopin 50% bacoside a/b 600 mg with my breakfast.

(I also take a whole list of other stuff)

I take all of these products mostly because the cost is very low as I sell these products as well as take them. If someone is on a tight budget, I would NOT recommend starting with unproven therapies such as Aniracetam, Piracetam, Oxiracetam, or Alpha GPC, etc. -- UNLESS, possibly, of course, if you happen to be elderly or demented. Once you have thoroughly investigated the therapies that have been shown to really work in healthy folks, if you by chance have some spare cash, let us know and we can recommend some "dietary supplements..."

While there may be some evidence that suggests that these dietary supplement products may be effective in elderly or demented subjects, there is zero solid evidence that the conventionally accepted nootropics would affect memory functions of an individual with a perfectly functioning memory in the same manner. It is theoretically possible, but unproven nonetheless.

On the other hand, we do have solid evidence from randomized, double blind, placebo controlled trials in healthy subjects that suggest that prescription-only drugs such as Provigil AKA modafinil, Aricept AKA donezepil HCL, and Ritalin AKA Concerta AKA methylphenidate can improve short and long term memory functions -- once again -- in healthy subjects...

Bacopa has also been researched in healthy subjects: the following two double blind studies suggest benefits for healthy subjects as well:

This and this too

Cross references; where applicable:

http://www.ncbi.nlm....l=pubmed_docsum

Adrafinil is not currently illegal or a controlled substance in the USA, so it can be imported without the legal threat imposed from Modafinil -- a schedule IV controlled drug in the USA.

Peace out. I'm off to bed
[tung]

Edited by nootropikamil, 04 June 2006 - 08:26 AM.