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#depression

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#1 donaldlove32

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Posted 15 July 2021 - 02:24 PM


Hi, I have been battling for a long time with neuro/hormonal/ psych problems you name it. I basically eat, sleep shower, talk, have all organs and have good life. But my brain is dead like I feel like a zombie. The symptoms started years ago by extreme stress that led to my mental collapse, I dont recall a significant trauma to the head. A lot has happened since. I have been put on antidepressants zolfot was the first then wellbutrin then viibrid, none worked and eventually I just felt very very numb, irritable. I tried ketamine therapy, testosterone therapy and many many different medicaions and supplements. I even did TMS. I recently started growth hormone (been doing that for a few months. But I have the following symptoms which I see are very very very rare but I can relate and have seen posts by people. Many symptoms overlap with pssd but I just havent found a solution. I have tried amphetamines, adderall is ok, others dont work. The only thing and I repeat the only things that helps the most that makes me feel closest to normal but still very far is modafinil. It kind of reawakes me, makes me more confident, more aware of whats going on. Without it im literally braindead. 

My symptoms are

Lack of arousal, minimal to no response to stimuli, lack of mental clarity, lack of focus, no sex drive/libido, numb and shrunk penis, lack of energy, tired and fatigued all the time, dont have strength, motivation to do things, I isolate my self from others and don't have the confidence of what to say because i simply CANT. Like I have lost my ability to do all that where as before it was natural and came to me, feel nothing but anger, hatred, no well-being, irritability, don't live in the moment, live in the clouds, have to read things a million times so they stick and even then it barely sticks in my head anyway. I dont feel joy from what I do, no pleasure. This is beyond your ordinary depression, its something else, something clogged in my brain.  Do others and or have others had these symptoms? From what I see this is very tough to come out from. I need your help to see what I can do heal. Thank you.


Edited by donaldlove32, 15 July 2021 - 02:26 PM.


#2 BobG

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Posted 20 January 2023 - 11:17 PM

Hello. I'm just looking for this kind of information. I want to start taking сbd products. But the problem is, I don't know anything about it. Now there are a lot of sites with сbd products, but I do not know which one can be trusted. I hope there are people here who understand this and help me. Thanks in advance for your help!



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#3 healthmysteries31

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Posted 30 January 2023 - 04:50 PM

Many of our symptoms overlap I think. I have posted my story here but didn't get a reply.

 
 
Maybe we can exchange some ideas if you are still here. My symptoms didn't start with a clear stressor.
 
I have read of many of such cases. They are mysterious, very unpleasant but don't seem to respond well to known treatments.
 
My symptoms have been lessened somewhat with lifestyle changes(mainly diet) and some supplementation but they have only been made more tolerable but weren't fixed.
 
The best supplement I found so far is magnesium. It helps with most symptoms but needs to be taken several times a day while avoiding taking too much because of the laxative effect.
 
So i don't really have found an answer yet. 
 
One idea that I have, this is completely unscientific just a guess:
 
 
From what I feel in my body that I am stuck in some kind of stress system/nervous system overactivation.
 
So what could happen is that for some reason the stress system in the body is overactivated for a longer period of time, could be due to illness, could be due to stress or something else.
 
For some reason once the body remains in that state for too long it adapts and gets stuck in that state.
 
The final stage of this is exhaustion on a physical and mental level and eventually a shut-down of the brain which is seen as fatigue, lowered cognition, lack of motivation, lack of joy etc.
 
At least in my case I would describe my state as wired but tired. I also have mildy elevated adrenal hormones which does suggest that the body is under some kind of stress or at least acts like it is responding to a stressor.
 
Stimulants or antidepressants or anything that increases neurotransmitter levels wouldn't be successful in this case as it is a result of exhaustion.
 
Stimulants may improve the problem for a while, but at the same time worsen the overactivation and wouldn't fix the general exhaustion of the system.
 
Like a person that has burnout due to overwork, taking stimulants would only temporary improve the problem.
 
When I take stimulants I notice some improvements, at the same time they make me uncomfortable and increase my inner tension.
 
Antidepressants don't seem to work as they have  a short limited effect but it seems to brain just adapts to them or even tries to shut itself down once it is pushed.
 
This could be because in the final stage of this stress system or nervous exhaustion you are just too burned out for some artificial fix. The fuel is long gone, igniting it with a chemical doesn't work anymore.
 
Now this is just pure speculation based on what I have noticed in my own body.
 
Does this resonate with you? Do you also experience this wired but tired state?

Edited by healthmysteries31, 30 January 2023 - 04:57 PM.






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