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When will scientists figure out how to reverse DNA damage from UV radiation?

dna damage sun damage crispr skin aging

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#1 JBForrester

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Posted 02 January 2022 - 06:41 AM


It’s the one thing in aging that has not been figured out yet. Could CRISPR solve it? Do we have any leads or hopes?

#2 Astera

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Posted 03 January 2022 - 07:01 AM

An Australian listed biotech company, Clinuvel, is now trialling their principal drug (afamelanotide) specifically in DNA repair in the condition xeroderma pigmentosum (XP). XP is a rare genetic disorder with a life expectancy of 37 years where UV light causes horrendus damage to the skin and explosion in cancerous skin growths. People with this condition have defects in their DNA repair mechanism. The first clinical trial just started late 2021 and the drug they are using is already approved for another condition and is being used in Europe and the US and is also approved in Australia and Israel. Don't expect to find it at your pharmacy as it is strictly controlled a full year's treatment for people being treated with it can be up to USD 100,000. Full details here of XP and the clinical trial and discolusre that I'm a long-term shareholder in the comapny.

 

https://www.clinuvel...a-repair-study/


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