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Best co-factors to take with SAM-e?

undermethylation histamine sam-e

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#1 Kris111

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Posted 01 February 2022 - 09:56 AM


Hi Folks, could you please help me?

 

Quick background: I have undermethylation confirmed by both whole body histamine test and presence of genetic polymorphisms.

 

I am planning to take SAM-e supplement (200mg) as one of the first supplements to try out.  

 

What other supplements should I take with SAM-e as helpful cofactors?

 

FYI - I first tried B-vitamins as an initial "foundation" to built.  Taking B-right of Jarrows gave me excessive fatigue and seem to be histamine releasing in my case, even though it is supposed to have the right kind of methyl folate.  Possibly because of Niacin in the B-complex?  Anyway, I decided to stop taking B-complex vitamins and decided to directly focus on SAM-e for methylation.

 

 


Edited by Kris111, 01 February 2022 - 10:50 AM.

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