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The Olive Oil Signal in the Baati Study

#c60 #oleocanthal #olive oil

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#1 sensei

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Posted 02 February 2022 - 03:47 PM


Oleocanthal, is a known constituent in EVOO. Oleocanthal inhibits MTORC1, P3IK, at nanomolar concentration, and likely PDPK1.

I propose that the primary longevity signal seen in the EVOO and C60 arms was due to the action of oleocanthal on the MTORC1/PI3K pathway, and the dose administered.

Recently, PDPK1 inhibition has been shown to reverse cellular senescence.
Additional longevity effect is likely due to mitophagy and or mitochondrial rescue by the C60.
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#2 joesixpack

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Posted 08 February 2022 - 10:02 PM

You are probably correct. The rats that were just given olive did much better than the rats that were given water.


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