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Amino Acid Ergothioneine Extends Average Lifespan 21% in Mice

ergothioneine

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#1 Decimus

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Posted 24 March 2024 - 12:01 AM


I have perused the supplements forum and I did not find anyone discussing this.  If I missed an ongoing thread please delete this, otherwise, is anyone experimenting with this?  The safety profile appears promising and the results are outstanding for a mouse model.  The only caveat is that the outcomes may be gender specific.  The supplement has been available for at least a decade, but most of the research and supplementation appears to be happening in Japan. 

 

https://www.nmn.com/...ive-enhancement


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#2 timedilation

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Posted 24 March 2024 - 12:42 AM

Apparently, several species of mushroom are pretty high in ergothioneine.  Another reason to keep up your mushroom consumption


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#3 Gal220

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Posted 24 March 2024 - 04:40 PM

Apparently, several species of mushroom are pretty high in ergothioneine.  Another reason to keep up your mushroom consumption

 

" Dubost and colleagues (2007c) reported that ergothioneine makes up from 210 to 2,590 mg/kg of the dry weight of most commonly consumed mushrooms in the United States, including Agaricus bisporusLentinula edodesPleurotus ostreatus, and Grifola frondosa.... Therefore, it is reasonable to conclude that mushrooms are the best-known source of ergothioneine. "

 

https://www.scienced...s/ergothioneine

 

Seems we have the most of it at 18 

"It increases gradually between 11 and 18 years of age and reaches the maximum value of 3.7 mg/100 mL at the age of 18 years. "

 

 

A few tinctures offering over 100-500mgs per serving, but you could dose however you want.  Unfortunately not familiar with any of the brands

 Lyfetrition looks like a reasonable brand and make several other tinctures, maybe someone else can chime in on that

 

 

Most capsules give 5 mg of it except for Prohealth(they off several longevity supplements) which gives 25mg($1.33 per cap though)

https://www.amazon.c...n/dp/B0CPHLBHC8

 

 

 

From their marketing page

https://www.prohealt...plan=3923050596

 

  • Supports longevity by aiding in telomere length maintenence 1
  • Combats oxidative stress in the brain to support cognition 2
  • Protects the heart and is associated with reduced cardiovascular mortality 3

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