Posted 02 February 2007 - 08:09 PM
I take a liquid extract (tastes pretty good, too) that is standardized to 30% punicaligin. The daily dose I use is equivalent to 125 mg of the 30% extract, so that would translate to 37.5 mg punicaligin. A 50 mg tab of 40% would be 20 mg punicaligin.
According to [PMID: 17179594], one liter of commercial pomegranate juice "purchased from local stores" contained 317 +/- 17 mg of phenolics, of which 70% was punicalagin, however they also claimed "Total phenolics in fresh
single-strength pomegranate whole fruit juice contained 2,216+/-70 mg/L
(95% punicalagins)". I'm not sure what "whole fruit juice" means in this context, but think it might include the carp- the whitish stuff between the seeds that you normally don't eat. That is a rich source of phenolics, as is the rind.
You might not want to consume a massive amount of pomegranate, because like some other fruits, it inhibits P450 3A and 2C9 in the gut, and can impact the blood levels of drugs that are metabolized by those p450s. It is like grapefruit in that regard, but is not as potent an inhibitor as grapefruit.