ANOTHER menaquinone-free regimen! Sacre bleu! K2 seems like a no brainer in terms of risk:benefit. Also, is your diet rich in w-3 FA? If not, you might want to consider flax or fish oil. Do you track your nutrient intake?
You might consider adding modest doses of some 'dietary' glycation inhibitors (other than p5p) like taurine, carnitine, and carnosine/b-alanine.
May your metformin usage be side effect free!
Oh, I forgot to mention that I take taurine and beta-alanine. It is possible that taurine inhibits the absorption of beta-alanine and thus I take them on alternating days.
I don't take menaquinone because I get enough through my diet (often multiple times the RDI).
I'm a bit scared about w-3 fatty acids because long lived animals seem to have membranes low in unsaturated fats and rich in saturated fats. For example shorter-lived laboratory mice have more w-3 in their membranes compared to longer-lived wild-derived mice. Offspring of human nonagenarians have a lower content of PUFAs in the membrane of their ertythrocytes then controls. Much more evidence is cited in the article.
See: Piotr Zimniak. Detoxification reactions: relevance to aging. Ageing Research Reviews, 2008, 7: 281-300.
Are you still taking ubiquinol? Evidently we produce plenty of ubiquinol up until at least the age of 25.
What do you mean by w-3 fatty acids? Excuse my ignorance
No, I don't take ubiquinol any more.
I used the w as a symbol for the Greek omega, so I was talking about omega-3.
