I see conflicting information with Reverapure in that on the NSI supplement facts it states that it has "Resveratrol (from 200 mg Polygonum cuspidatum extract standardized to 50% resveratrol) (root) ResveraPure®",
NSI Resveratrol -- 100 mg - 60 Capsules
Supplement Facts
Serving Size: 1.00 Capsule
Servings per container: 60.00
Amount Per Serving % Daily Value
Resveratrol (from 200 mg Polygonum cuspidatum extract standardized to 50% resveratrol) (root) ResveraPure® 100.00 mg *
*Daily value not established.
http://www.vitacost....SHOPFEED-nextagHowever when you go to the Naturex supplier raw material website, manufacturer of the registered trademark product ResveraPure®, they only claim 8% total resveratrols, not even trans:
http://www.naturex.c...tactiv02_gb.htmResverapure®
(Huzhang extract)
Polygonum cuspidatum
Standard: 8% Total Resveratrols
It is contradictory information like this that should make us wary of some dietary supplement companies and their so called credibility. It is also insulting to the consumer that these companies are so careless in their documentation of products. I agree we need the Consumer Labs results to know what we are really getting. It makes we wonder where their "values" are and do they only make these
supplements for money sake alone and don't they use these products themselves. I would like to believe in an ideal world that people like us who seek out this information and products to better our health and lives should be the ones to formulate and manufacture supplements to spread the benefits to others.
On another matter, the high levels of emodin also concern me because they are considered cytotoxic, not just laxative. Emodin like resveratrol strongly inhibits angiogenesis for wound healing, inhibits cell growth, inhibits androgen receptors, etc., and while this may seem good for blocking abnormal growth process, ie, prostate cancer cells, this also could have untoward side effects such as diminished wound healing, weakened tendons, ligaments, poor healing of muscle strain, loss of libido, loss of muscle mass from inhibited repair processes, possibly sounds like the syndrome of andropause?? What about increased risk of hemorraghic stroke if blood vessels cannot repair properly. Some inhibition of angiogenesis is valuable to decrease vascular endothelial proliferation and intimal lining thickening that lead to athersclerosis (one benefit of resveratrol), but surely some angiogenesis is needed to maintain vascular integrity and strength. Interestingly, in one animal study resveratrol at a higher dose 20 mg/kg increased both fertility and testosterone levels simulataneously and since it has an anti-aromatase effect could prevent the conversion to estrogen - thus resveratrol may be helpful for andropause, but emodin may not.
"The treated group was administered by gavage 20 mg/(kg . d) of trans-resveratrol suspended in 10 g/L of carboxymethylcellulose for 90 d, whereas the control group received only carboxymethylcellulose during the same period. Serum concentrations of gonadotrophins and testosterone were significantly higher in the resveratrol-treated group. We identified a novel activity of trans-resveratrol. The daily oral administration of this phytochemical to adult male rats enhanced sperm production by stimulating the hypothalamic-pituitary-gonadal axis, without inducing adverse effects"
Juan ME, Gonzalez-Pons E, Munuera T, Ballester J, Rodriguez-Gil JE, Planas JM.
trans-Resveratrol, a natural antioxidant from grapes, increases sperm output in
healthy rats.
J Nutr. 2005 Apr;135(4):757-60.
PMID: 15795430 [PubMed - indexed for MEDLINE]
2: Eng ET, Williams D, Mandava U, Kirma N, Tekmal RR, Chen S.
Anti-aromatase chemicals in red wine.
Ann N Y Acad Sci. 2002 Jun;963:239-46.
PMID: 12095950 [PubMed - indexed for MEDLINE]