5 replies to this topic

[eyu100]

Has LysoSENS made any progress since February? The bacteria that degraded 7-ketocholesterol were found, but has any other progress been made?

[John Schloendorn]

I would ask you for just a few more days of patience, until the Methuselah Foundation will be able to release the videos from the Edmonton Aging Symposium, where lead investigator Bruce Rittmann gave an eloquent update. In brief, the most recent news is the development of a method to determine 7KC degradation pathways in our numerous isolates, so that the most promising ones can be selected for further development, and successful application to a few species.

[John Schloendorn]

And here they are.

[ganeshge]

Although, I do agree with a enzymatic approach to degrade 7KC, I also think, there could be possibilities where 7KC could be soluble in any of the organic compounds which would also help in dissolving and removing 7KC.

For example, is it possible, that 7KC is soluble in polyphenols such as proanthocyandins of Pomegranate, so that it can be removed

In summary, my point is, not only we have to look into degrading 7KC as the only pathway, but also look for compounds that can solubilze 7KC and remove from the body..

[jmmathieu]

Anything that would solubilize 7KC and remove it intact (though this is way too simplified) would also remove a ton of other things and most likely kill you.

[ganeshge]

Dont you think, the new research on the use of Glisodin (oral SOD) to reverse atheroscelorisis could provide some leads on removal of 7-KC?

http://www.lef.org/m...lerosis_01.html