Hi,
Can anyone share their experience of this brand with me?
My doctor recommended this brand.
How does it compare with other 'big name' multiples?
http://www.purecaps....y00.asp?T1=PHN3
Many thanks for your help in advance.
Posted 11 May 2007 - 04:38 PM
Posted 11 May 2007 - 04:41 PM
Posted 11 May 2007 - 05:21 PM
Posted 11 May 2007 - 05:31 PM
Good company, but that product is awful. Alpha tocopherol without the other vitamers, niacinamide, obsolete selenium, and way too much manganese. Green tea should also be taken away from minerals to keep it from binding to them and preventing absorption.
Posted 11 May 2007 - 06:34 PM
Good company, but that product is awful. Alpha tocopherol without the other vitamers, niacinamide, obsolete selenium, and way too much manganese. Green tea should also be taken away from minerals to keep it from binding to them and preventing absorption.
small amount of a-t... given the amount of g-t in the normal diet, i dont see 100iu being a problem
everything ive seen against niacinimide is anecdotal at best
theres nothing wrong with selenomethionine... it by far got the most hard evidence proving its efficacy
the manganese is a bit high, but nothing to worry about
Posted 11 May 2007 - 06:56 PM
Given the high price of this company's supplements, they should have no drawbacks and be better than their competitors. You can't get away with saying that the ingredients shouldn't hurt you too much or are almost as good as a cheaper product.
You need to get at least twice as much gamma as alpha. 100 IU = 66 mg alpha. It would take a bizarre diet to give you 132 mg of gamma without an extra supplement.
I see that you couldn't come up with a single reason someone should take niacinamide when they could be taking inositol hexanicotinate instead. Nuff said.
In head to head comparisons, Se-Methylselenocysteine greatly outperforms selenomethionine. It's newer, so of course it would have fewer studies.
The manganese IS something to worry about. You are being reckless.
http://www.aor.ca/in...ho_minerals.php
Posted 11 May 2007 - 07:40 PM
Posted 11 May 2007 - 10:37 PM
again the optimal g:a ratios are at best anecdotal... no one REALLY knows what is best
i HONESTLY do not see an extra 100iu alpha as being even a SLIGHT risk
if i had to choose, i would choose s-mc over s-mt, but that in no ways says s-mt is 'obsolete' or in any way ineffective
niacinimide has a pretty long history of usage and efficacy. the only reason ive ever heard anyone speak down about it, is a single anecdotal study done on yeast. which is not even enough to make me look twice at it.
i have yet to hear of a SINGLE case of manganese toxicity, other than miners inhaling it.
ive read that article by aor, but they dont mention how high the intake was... was it 10, 50, 100mg per day? if you have people consuming 50mg per day, its not fair to say that 10 could be a risk. thats not solid science. take a look into manganese metabolism and youll see why, unless your diet is abnormally high in manganese, 10mg supplemental is not a big deal.
Posted 12 May 2007 - 02:46 AM
Posted 12 May 2007 - 01:53 PM
Posted 12 May 2007 - 09:02 PM
proof 100iu supplemental causes 'severe gamma E' depletion?
yeast studies. not humans.
corellation is not causation and i would also say the manganese is a dry cell battery is a bit different than the aspartic acid salts in that purecaps product.
i think what would be best is to print up an ingredient list from ortho-core and multi-basics, and bring it to your doctor. voice any concens over vitamin-E or manganese you may have, and see what his opinions are about the difference between the two products.
Posted 14 May 2007 - 01:42 AM
Arrogance and ignorance are a terrible combination.
Supplementation with alpha-tocopherol increased serum alpha-tocopherol levels, while producing a marked decrease in serum gamma-tocopherol
We show that physiological concentrations of nicotinamide noncompetitively inhibit both Sir2 and SIRT1 in vitro.
We know the mechanism of manganese's toxicity and we have scads of people who have been hurt by it. Why would you subject yourself to this risk when high dose manganese is pointless? To save $5 a month?
...
Posted 14 May 2007 - 08:18 PM
so... lower blood levels of g-t directly after ingestion of a-t, somehows equals severe g-t depletion...
ok
im not a chemistry major, but i know that different forms of the same mineral have drastically different levels of toxicity.
sodium selenite, s-mt & s-mc... would all yield selenium + something, correct? but the amounts of each you can safely consume vary pretty drastically.
i know of people who have been taking perque's multi which has 15mg of manganese for 10+ years, and show no signs of manganese toxicity.
Posted 14 May 2007 - 09:50 PM
Yes and no. If something is sufficiently neurotoxic, as MPTP was found to be, Parkinson's (or something similar) can occur after just one drug dose.Parkinson's doesn't show up until most of the dopamine-producing cells are gone. 10 years isn't long enough to guarantee safety.
Posted 15 May 2007 - 03:23 AM
If something has been depleted that means that it is lower. (BTW, do you believe that lowering blood gamma tocopherol is a good thing?)
Parkinson's doesn't show up until most of the dopamine-producing cells are gone. 10 years isn't long enough to guarantee safety.
Posted 15 May 2007 - 07:20 PM
that battery acid thing was 2-3 months?
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