Strattera seems like a catastrophic idea in such cases, it increases levels of norepinephrine.
OCD has very solid links to serotonine deficiency, but behavior therapy is also shown to be very effective.
Regarding serious, clinical anxiety: If ashwagandha, gaba and the other 'sedative' supplements that
restore GABA don't work, there seems to be no way around medication. The protocol at
www.lef.org regarding anxiety seems to express that, as well. It mentions beta-blockers and
azipirones (e.g. "Buspirone"), which don't have the tolerance/addiction of benzodiazepines.
I guess benzos are still widely prescribed but they are just an emergency brake, and will
cause tremendous problems (GABA receptor downregulation -> dependence) rather fast.
Thats pretty much what I have been told and read. OCD is a serotonin issue, not a GABA issue, with some behavioral issues thrown in. Successful treatment of real OCD has a high success rate: SSRI and behavior modification or cognitive therapy or whatever flavor of retraining your brain you choose. Granted there are supplements that have been shown to increase serotonin or postively affect the serotonin system: tryptophan, 5-htp, St. John's Wort, SAMe, Rhodiola etc etc., my personal philosophy is that if your "disorder" or "disease" is clinical, as in affecting your daily life then the best course of action is to seek modern medicine. Then once you have fixed the disorder you can go about tweaking your nutritional, lifestyle and supplements. Then over time perhaps you can begin to (under the care of your medical practitioner) reduce the dosage of whatever pharmaceuticals you are on. For me things like OCD, or Panic Attacks, or depression if at a certain level need to be taken care of quickly so as not to alter the flow of your life (my opinion), if you lose your job, flunk out of school, have to go to treatment or whatever over such things then things are going to get a lot worse.
Now if someone has "OCD tendancies" or "a little anxiety in certain situations" or feels just "a little blue" or whatever then perhaps tackling that issue with supplements or lifestyle is the way to go, but again if you are "clinical", that is if your problem affects your functioning in daily activities (you can't compensate for it) then save yourself time, pain and more problems and go see a professional.