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Effexor and complete fatigue


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#1 spacey

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Posted 26 August 2007 - 02:25 PM


Awhile ago, I was prescribed Effexor for my depression, starting 37,5mg a day. The problem is, that ever since I started taking it I have some severe sleeping disturbances, I can't focus in school anymore, I'm both physically and mentally fatigued all the time. Moodwise the Effexor has helped but I'm so fatigued, I've started grinding my teeth in sleep. When I do actually manage to fall asleep. Even writing this takes some extreme effort for me, although I'm 16 and my mind should be in it's prime right now.

Anyhow, I was wondering if nootropics could help my condition, and maybe help me get back into normal sleeping patterns again and give me back the mental energy that I'm really starting to lose right now.

#2 Shepard

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Posted 26 August 2007 - 02:26 PM

Have you told your doctor and asked about alternative medications?

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#3 spacey

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Posted 26 August 2007 - 02:30 PM

Have you told your doctor and asked about alternative medications?


Uhm, no. I'm considering on doing so. If it would help, quite frankly I don't understand how it can cause me to become so fatigued it's extremely sedating yet it's causing me major issues with sleeping.

#4 Brainbox

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Posted 26 August 2007 - 02:37 PM

Why wouldn't it? Your doctor should be the basic authority for any medication. Until you do not trust him / her anymore, but then you should find another doctor. :)

#5 ikaros

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Posted 26 August 2007 - 04:22 PM

It's incomprehensible why your doctor decided to use such a psychiatric a-bomb like effexor, especially considering your age. The effects you are describing are very common with Effexor (been there done that). They should subside usually in 3 weeks max. Though I highly recommend you look into more benign options like perhaps alternative methods (e.g. rhodiola, hypericum perforatum, but not piracetam or other advocated cholinergic memory boosters - they tend to aggravate depression), if medication is still warranted, modafinil is a great motivation enhancing agent and fluoxetine (SSRI) is considered the most weakest of its class, so you have less chance of messing things up, but greater chance of improving your depression.

#6 spacey

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Posted 26 August 2007 - 04:54 PM

It's incomprehensible why your doctor decided to use such a psychiatric a-bomb like effexor, especially considering your age. The effects you are describing are very common with Effexor (been there done that). They should subside usually in 3 weeks max. Though I highly recommend you look into more benign options like perhaps alternative methods (e.g. rhodiola, hypericum perforatum, but not piracetam or other advocated cholinergic memory boosters - they tend to aggravate depression), if medication is still warranted, modafinil is a great motivation enhancing agent and fluoxetine (SSRI) is considered the most weakest of its class, so you have less chance of messing things up, but greater chance of improving your depression.


Psychiatric A-bomb? Is this going to screw up my mind completely? I have no idea why he chose just that one but I trusted his competence, maybe I was wrong doing so. I will see to modafinil and fluoxetine.

Also, if I take nootropics togheter with my medication will it screw things up more or is it safe?

#7 luminous

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Posted 26 August 2007 - 05:18 PM

spacey--From the sound of it, there's probably a good likelihood that you might quit taking the Effexor. In case that's true, I want to share something about Effexor that I went through--and that my doctor never bothered to warn me about.

I took Effexor for a short time for mild depression about eight years ago. I gave it five months, but I found that the drug wasn't helping me. I was sluggish, depressed and gaining weight--so my doctor advised that I quit taking it and switch to Wellbutrin. I did so.

About the second day after the switch, I was startled from my sleep in the middle of the night because I "heard" something. After waking up and looking around, I realized that what I was "hearing" was the sound of my own eyes turning from side to side! It was a noise not unlike the sound that a Star Wars light sabre makes. I tried to ignore it and went back to sleep--hoping that maybe it was just a bad dream. But when I woke up in the morning, the eye problem was much worse. Not only did I hear the noise, but I was getting an electrical-shock sensation throughout my body whenever I moved my eyes even a little bit.

The only new change in my habits that I could think of was that I had started taking Wellbutrin. But I'd used Wellbutrin a few years earlier with no ill effects. So I was terrified. I thought I was dying and/or having a stroke. I called the after-hours nurse (it was Sunday) and recounted my symptoms, wondering if Wellbutrin ever had this kind of effect on people. I didn't even think to mention the Effexor, because I had quit taking it. While Effexor didn't work too well for my depression, it certainly didn't cause anything remotely like what I was now experiencing.

Lucky for me, the nurse was sharp enough to ask if I had recently stopped taking any medication. I thought that was a strange question, but I told her that I had indeed stopped taking Effexor. I was suprised when she told me that my symptoms were likely entirely due to stopping the Effexor. I almost didn't believe it, but after getting off the phone, I went online to see if there was any information about this curious effect. Was there ever! I found thousands upon thousands of hits on a google search of "effexor withdrawal". There are entire websites devoted to it. Some of the symptoms are much worse than mine. The common thread seems to be the "electrical shock" feeling, sometimes described as "brain shivers". I even found a few people who tied that feeling to eye movement, just like me. What scared me the most was that some people said the bad effects were continuing for weeks, months, even years.

At any rate, my symptoms slowly subsided over two weeks--not fast enough, but I lived through it. If you quit Effexor, you may not experience such ill effects--but if you do, be sure to discuss it with your doctor before panicking like I did.

#8 ikaros

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Posted 26 August 2007 - 06:44 PM

Psychiatric A-bomb? Is this going to screw up my mind completely?


Not likely if you haven't been taking it for a very long time. The potential screw-up is just more of a functional temporary neurologic disturbance. Don't worry, but be sure to slowly come off the drug, this ensures that you will avoid the withdrawal and all the other annoying side-events that might come up.
Effexor is not a bad drug, it's only bad when used in wrong circumstances. Effexor is by common use reserved for the most clinically depressed cases i.e. you have to be really really ****ing depressed so that your normal everyday functioning is not anymore possible. It's just too damn powerful, that's it.

#9 rebuild101

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Posted 27 August 2007 - 11:20 AM

The common thread seems to be the "electrical shock" feeling, sometimes described as "brain shivers".

Yikes! Though you don't sound like you're thinking of trying it, Paxil withdrawal can also produce these shocks. It is not a pleasant experience at all!

#10 spacey

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Posted 27 August 2007 - 04:05 PM

Not likely if you haven't been taking it for a very long time. The potential screw-up is just more of a functional temporary neurologic disturbance. Don't worry, but be sure to slowly come off the drug, this ensures that you will avoid the withdrawal and all the other annoying side-events that might come up.
Effexor is not a bad drug, it's only bad when used in wrong circumstances. Effexor is by common use reserved for the most clinically depressed cases i.e. you have to be really really ****ing depressed so that your normal everyday functioning is not anymore possible. It's just too damn powerful, that's it.


Well I'm slowly getting of the Effexor now though, it was causing me too much insomnia, and while sleeping I could feel vibrations in my brain, I think it may have been a bit too strong for my young mind or something..

So far I haven't experienced any nasty side-effects besides being very anxious and tired. But it's only gone a day so we'll see. My doctor recommended me to start taking Zoloft instead, is it better?

#11 ikaros

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Posted 28 August 2007 - 12:13 PM

My doctor recommended me to start taking Zoloft instead, is it better?


It's certainly milder than Effexor, although Prozac and Lexapro should be the first meds to be tried if antidepressants are really warranted. Also consult with your doctor the option to use rhodiola or tyrosine/5-HTP. For some they seem to work quite well. Good luck.

#12 spacey

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Posted 28 August 2007 - 08:51 PM

It's certainly milder than Effexor, although Prozac and Lexapro should be the first meds to be tried if antidepressants are really warranted. Also consult with your doctor the option to use rhodiola or tyrosine/5-HTP. For some they seem to work quite well. Good luck.


I've been hearing alot about Rhodiola supplementation, but will it be equally effective as an SSRI?

#13 shamus

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Posted 29 August 2007 - 01:16 AM

I've been hearing alot about Rhodiola supplementation, but will it be equally effective as an SSRI?



No where near, the side effects wouldn't compare however.

And consider the fact that you may not even need the extra benefit of the Effexor.



I would move to the Zoloft personally, it's said to have less side effects and all of those who I've talked to about their usage seem fairly happy with it (a fair amount of people, I work in a pharmacy).


Good luck with it all spacey!

[thumb]

#14 niner

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Posted 29 August 2007 - 02:09 AM

I'll second the Lexapro (or its racemic cousin, Celexa, if you want a low cost option). It has a great side effect profile. It's probably the best of the SSRIs in that regard. I would not have gone with Effexor as a first-line agent, but I don't consider it to be the poison that some do. It does have definite withdrawal effects; tapering off will tamp these down a lot. You might want to talk to a psychiatrist instead of your family doctor. Psychiatrists just have way more experience with these drugs.

I should add that any bothersome side effects should be discussed with your doc. Most people wind up experimenting with a few different drugs before they find one they are happy with, and what works for one person may not work for another. Don't just let the doctor give you a prescription and send you on your way; there should be a couple followup visits to make sure everything is working. If that's not happening, I'd suggest a different doc.

#15 wkdnlazy

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Posted 29 August 2007 - 08:00 PM

Similar bad experience here. I went to a doctor about a year back looking for Provigil and was instead prescribed Effexor XL 75mg once daily for a month because he didn't know what Provigil was ! I reluctantly took the Effexor then binned them after only 3 days because they exacerbated my tiredness and left me feeling 'wired'. Needless to say I have a new doctor now !

#16 spacey

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Posted 10 September 2007 - 08:28 AM

Well, I've talked to my doctor and we're going to try Wellbutrin now, he claims it shouln't make me so fatogied during the days and we'll combat the insomnia with Stilnoct(Zolpidem).

Any thoughts on this? Will it be a better combination? Although Zolpidem is Schedule-IV here in Sweden and it kind of worries me that he prescribed it to a 16-year old but if it works then it's good.

#17 shamus

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Posted 10 September 2007 - 11:09 AM

Stillnox (zolpidem) seemed to leave me in the morning thinking I haven't had a wink of sleep.

It seemed that all my sleep was insane REM dreaming sleep, however this contradicts studies done on stillnox (i think).

#18 sp0sp0

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Posted 16 September 2007 - 07:21 AM

I took effexor xr, around 215 mg, for about two years during my school years. It was a big mistake. I slept more than I did without it. I would sleep all day and I would concentrate more on social situations and distractions rather than studying. For about 1.5 years I fell behind in school.

If you have sleep problems, I suggest you talk to your doctor.

I just started taking wellbutrin yesterday. I hope my situation improves with this. Sleeping too much is a big problem and effexor did not help me either. It made me sleep way more. In addition, while I was on it I did some regrettable social interactions that further caused me more psychological problems than I already had.

#19 luv2increase

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Posted 16 September 2007 - 12:53 PM

I took effexor xr, around 215 mg, for about two years during my school years. It was a big mistake. I slept more than I did without it. I would sleep all day and I would concentrate more on social situations and distractions rather than studying. For about 1.5 years I fell behind in school.

If you have sleep problems, I suggest you talk to your doctor.

I just started taking wellbutrin yesterday. I hope my situation improves with this. Sleeping too much is a big problem and effexor did not help me either. It made me sleep way more. In addition, while I was on it I did some regrettable social interactions that further caused me more psychological problems than I already had.



I'm sorry it took you 2 full years to realize that effexor was severely interfering with your sleep. I hope wellbutrin will be more helpful.

#20 Evolutionary

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Posted 17 September 2007 - 11:39 AM

Spacey, do you remember the "permanent increases in intelligence" thread? Wonder how tracer is doing now.

#21 spacey

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Posted 17 September 2007 - 12:21 PM

Spacey, do you remember the "permanent increases in intelligence" thread? Wonder how tracer is doing now.


Yep I remember it, tracer made some other topics following it up slightly but I can't remember what he said about it. Why are you wondering though?

#22 Evolutionary

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Posted 17 September 2007 - 12:30 PM

If tracer increased his intelligence using the nootropics that he mentioned, and has still maintained his increase until today, maybe you can use the nootropics that he used to help your fatigue. There may be some overlap between intelligence-increasing nootropics and fatigue reducing nootropics.

#23 spacey

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Posted 17 September 2007 - 07:16 PM

If tracer increased his intelligence using the nootropics that he mentioned, and has still maintained his increase until today, maybe you can use the nootropics that he used to help your fatigue. There may be some overlap between intelligence-increasing nootropics and fatigue reducing nootropics.


Yes, I was certainly thinking about something in the lines of that. Although he also combined his nootropic regimen with several hours of NP and image streaming, which I suppose would be hard for me to do at such extensive lengths during the days at least, but I should still be able to somewhat reproduce his daily routines. I'll try and PM him to ask how things went.

#24 luv2increase

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Posted 17 September 2007 - 11:35 PM

If tracer increased his intelligence using the nootropics that he mentioned, and has still maintained his increase until today, maybe you can use the nootropics that he used to help your fatigue. There may be some overlap between intelligence-increasing nootropics and fatigue reducing nootropics.


Yes, I was certainly thinking about something in the lines of that. Although he also combined his nootropic regimen with several hours of NP and image streaming, which I suppose would be hard for me to do at such extensive lengths during the days at least, but I should still be able to somewhat reproduce his daily routines. I'll try and PM him to ask how things went.



Spacey, I don't think you should be taking lots of stuff. It seems that you already have a lot of chemicals going into your 'young' body and brain such as ambien, ritalin, and wellbutren.

#25 spacey

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Posted 18 September 2007 - 06:47 AM

If tracer increased his intelligence using the nootropics that he mentioned, and has still maintained his increase until today, maybe you can use the nootropics that he used to help your fatigue. There may be some overlap between intelligence-increasing nootropics and fatigue reducing nootropics.


Yes, I was certainly thinking about something in the lines of that. Although he also combined his nootropic regimen with several hours of NP and image streaming, which I suppose would be hard for me to do at such extensive lengths during the days at least, but I should still be able to somewhat reproduce his daily routines. I'll try and PM him to ask how things went.



Spacey, I don't think you should be taking lots of stuff. It seems that you already have a lot of chemicals going into your 'young' body and brain such as ambien, ritalin, and wellbutren.


Of course, but if I would be taking nootropics I would probably want to lay off the pharmaceuticals eventually at least. I guess it comes down to what's best fo rme though.

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#26 power.bulls.x

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Posted 15 December 2007 - 02:57 AM

My doctor recommended me to start taking Zoloft instead, is it better?


It's certainly milder than Effexor, although Prozac and Lexapro should be the first meds to be tried if antidepressants are really warranted. Also consult with your doctor the option to use rhodiola or tyrosine/5-HTP. For some they seem to work quite well. Good luck.

i would say no to prozac zoloft has deprecated Prozac since it a newer gen of SSRI




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