8 replies to this topic

[garfildbg]

Iz it safe to take 1.25 mg of Deprenyl with 500mg of tyrosine. Is it 1.25 mg of deprenyl to much or too litle. Should I take them in the same time. Or I should take one first and then after some time another.

Thanke you! [lol]

[zoolander]

That all depend on what you are taking it for. The general consensus with deprenyl (selegiline) is that at lower doses it's more of a MAO-B inhibitor and tends to work better as an anti-depressant. The major concern with deprenyl is it ability to inhibit MAO-A at the higher dosages of 5-10mg. MAO-A inhibition is what tends to cause most of the problems such as reactions with tyramine based foods and hypertensive crisis.

At low dosages such as 1.25mg most people are safe. Some people do get anxiety and some side effects at the low dosages though.

So to answer you quesions.

1. Is it safe to take 1.25 mg of Deprenyl with 500mg of tyrosine. Is it 1.25 mg of deprenyl to much or too little?

First of all, how old are you? If you are between the ages of 20-40 then 1mg should be safe and sufficent. If you are between the ages of 20-30 then 1mg 3 days a week (Mon, Wed, Fri) is recommended.

Is it safe to take deprenyl with L-tyrosine? I would say yes. One would think that they would work synergistically. Personally I would use phenylalanine in place of tyrosine unless you are using N-acetyl-Tyrosine.

2. Should I take them in the same time. Or I should take one first and then after some time another.

Take the tyrosine or phenylalanine (500-600mg) on waking at least 20-30 minutes away from food.

then take 1mg of deprenyl with your first meal.

Rule of thumb here = isolated amino acids, especially the large neutral amino acids, should be taken on an empty stomach to avoid competive inhibition of the amino acid at the blood brain barrier.

Take deprenyl with food alway.

[zoolander]

DO NOT play around with higher dosages of deprenyl without consulting your doctor. I cannot stress enough the dangers of messing prescription pharmaceuticals

[garfildbg]

Thanke you for your answers.

I would like to encrease my memory and learning abilities. I am 25 y.o student of dental school in Belgrade Serbia.

[spacey]

Thanke you for your answers.

I would like to encrease my memory and learning abilities. I am 25 y.o student of dental school in Belgrade Serbia.

Well "personally" I don't even dare touch Deprenyl, but I suppose that's because I'm on alot of prescription meds. You should try Desmo/Vasopressin for memory and learning, and maybe some Huperzine + Racetam?

[luv2increase]

Well "personally" I don't even dare touch Deprenyl, but I suppose that's because I'm on alot of prescription meds.

No, it is because you are a teenager. Don't talk about it so badly. He is 25, so it wouldn't be bad for him (who knows for sure) at the dosages that zoolander posted above.

You should try Desmo/Vasopressin for memory and learning, and maybe some Huperzine + Racetam?

Desmopressin and vasopressin are more for an acute increase in memory and learning. It isn't something that should be referred to for the first thing try either. Start of with the basics. This consists of a racetam and a choline source. You could also add ALA and ALCAR with this if you'd like.

I don't think that huperzine-a is a good route to start off with for simply increasing acetylcholine levels either.



Come on spacey, get with it.

[zoolander]

For memory I would recommend an acetylcholine esterase inhibitor (AChE I). I have been using galantamine for about a year or so now and I get as many comments from people on my memory as my girlfriend does for her skin which is a lot.

Galantamine (4mg) in combination with deprenyl is a fairly strong stack for memory.

I would start at 4mg of glanatmine with food. Be careful about increasing the dose. Higher dosages (8-16mg) can cause nausea for some

[shifter]

I'm 25 and the doctor prescribed me 5mg Selegiline per day which I did for several months. No problems or altered mood etc

However, i've cut it down as that much may be a bit overkill.

For arguments sake though...
What are the consequenses to health if you were to inhibit 100% of MAO-B as a 25 year old for the rest of your life? (lets say you can do without the tyramine foods). What happens to the dopamine and phenylethylamine if they dont get broken down? Does the brain just stop producing it? Does it keep building up? Will it increase lifespan still or is there a point where you just end up going backwards with your goals instead or forwards.

The consensus is that 5mg per day for a 25 year old is too much. But what is it actually doing that is 'too much'?

[spacey]

Well "personally" I don't even dare touch Deprenyl, but I suppose that's because I'm on alot of prescription meds.

No, it is because you are a teenager. Don't talk about it so badly. He is 25, so it wouldn't be bad for him (who knows for sure) at the dosages that zoolander posted above.

You should try Desmo/Vasopressin for memory and learning, and maybe some Huperzine + Racetam?

Desmopressin and vasopressin are more for an acute increase in memory and learning. It isn't something that should be referred to for the first thing try either. Start of with the basics. This consists of a racetam and a choline source. You could also add ALA and ALCAR with this if you'd like.

I don't think that huperzine-a is a good route to start off with for simply increasing acetylcholine levels either.



Come on spacey, get with it.

I'm not talking bad about it, simply saying that personally I don't want to touch it. I don't see why you're constantly trying to find something to complain about when it comes to me. I do agree on Racetams + Choline source though, also why isn't Huperzine-A a good route to start off with?