Anders said:
It might turn out that without developing the right mindset life extension will not improve life quality, or will even fail (people with ennui doesn't take care of themselves or might decide to end their lives). What ways of thinking promotes zest for life? How can we help people overcome too low biological setpoints of their mood?
Albert Einstein once said, "The unleased power of the atom has changed everything save our modes of thinking and thus we drift toward unparalleled catastrophe." (New Your Times, May 25 1946)
And, as the saying goes - guns don't kill people, people kill people.
While we've yet to blow ourselves up, Einstein's message holds similar urgency today with Nanotech already here and Unfriendly AI a real possibility. The chance is great that humans will one day find more effective ways to leverage anger. Thus, it may prove helpful focus energy into developing mood altering drugs. Such drugs may mitigate future catastrophe by helping a large number of people to elevate depressed moods.
Actually, I think the development of sustainable mood enhancing products to be a relatively easy assignment. Crude yet somewhat effective mood enhancing drugs are already found in products like Prozac, Zolof, and Remeron. Set points in happiness are being elevated in people already.
Stephen Braun writes in "The Science of Happiness - Unlocking the Mysteries of Mood" (2000) that the "pharmacological Calvinism is, indeed, crumbling" - meaning we are seeing more use of mood enhancing drugs because they are working.
Braun says, "These drugs can alter the happiness set point-at least for a minority of users- in helpful ways, and often make that adjustment with a minimal of side effects. In short, when they work well, they are true happiness enhancer." (p53)
In answer to Anders' question about life extension and how we can help, I think we can be effective by introducing life extension and anti-aging to a wider audience by promoting proactive events and prizes. Currently underway is the Methuselah Mouse Prize: http://www.methuselahmouse.org/ - other ideas are to create a walk for life, walk to cure aging or a lottery for longevity.... we need more ideas!
As Ben Best once said, we need to become better suicide councilors.