12 replies to this topic

[HappyCamper]

Hi!

This is a basic stack for me, my brother and his wife as well as for my mother and father. Mother and father 67 yrs old, good general health, the rest ~35 yrs old, good general health. Aim for supplementation: increased general well being, improved memory function, alzheimerprevention and antioxidant functions. It's not very impressive at the moment, but I'll add one supplement at a time, here's the basic stack:

*EPA/DHA 1200 mg/800 mg
*Astaxanthin 4 mg
*Vinpocetine 10 mg
*Multivitamin ABC Plus Senior OR
Daily One Plus

First step is optimizing the vinpocetine dose, somewhere around 10-40 mg/daily depending on results. Second is to add Gingko to see if there's any synergism with the vinpocetine. Then in the following order:

S-PS 300-600 mg daily
Oxiracetam+choline source (input regarding dose etc. needed!)
Hydergine (input same as above!)

Any more antioxidants? Resveratrol? Any more antialzheimerspecifik supplements?

Thanx for a great forum!

[balance]

I would definitely add Blueberry. Ginkgo is a good choice, I noticed different results comparing ginkgo to vinpocetine, meaning both are a good idea to take if there's no financial need to make a choice. Resveratrol is generally a nice idea. Have you seen lef's Cognitex? That might give you some ideas. Also, something very often overlooked for protecting the mind against alzheimer and any other degeneration is Carnosine. I had an excellent 20 page document on it, can't find it right now, but lef's Mitochondrial energy optimizer might be a good bet. If not, focus on getting carnitine/carnosine/r-lipoic acid from some other source, these are all good at optimizing, improving, and repairing the mind. Astaxanthin is a good idea, also I'd try to get more DHA instead of the high EPA, as they see a lot of mental side benefits specifically from DHA and not EPA. Adequate Magnesium status for your mind can never hurt either. When it comes to antioxidants, the ones you really want for protection of your mind will be glutathione & SOD and catalase. Make sure you get adequate zinc, copper, manganese levels. I said adequate, not too much or too little. Some NAC with at least 2-3x as much vitamin C would help with the glutatione. Though a safer way is to consume whey protein shake, with preferably no lactose and sugars. Lef's SOD supplements in the form of endothelial defense (glisodin) and/or SOD with wolfberry might be a good choice for you if you believe in them.

Take it easy on the alcohol and soft drinks, and you should be fine.

Funny, i recently read this:

http://www.scienceda...80102222901.htm

It perfectly complemented my theory that alcohol is a feminine drink, and makes you feminine in certain ways. The composition of alcohol, it's effects on the body and mind is what I'm talking about. Yet people always associate it with males and a manly drink haha. Same with meat. Supposedly for the super male hunters, yet females benefit more from meat than males as far as i'm concerned, due to THEM being the iron deficient half of the planet, whereas the males are the iron overload group.

Edited by piet3r, 16 January 2008 - 09:12 PM.

[health_nutty]

1) Turmeric and aspirin break up amyloid plaque.
http://www.neuroreport.com/pt/re/neurorepo...#33;8091!-1
http://www.blackwell...59.2004.02800.x
2) Exercise
http://alzheimers.ab...-alzheimers.htm
3) Limit exposure to aluminum (anti-persperients, cookware, salt) to be on the safe side.
http://www.alzheimer...p?documentID=99
4) Keep your mind active (esp once you retire).
http://www.webmd.com...heimers-disease

Edit: added links

Edited by health_nutty, 16 January 2008 - 10:08 PM.

[niner]

I second the suggestions for Carnosine and Exercise in particular. Vitamin D is cheap and if you live in the developed world, there's a good chance you're deficient.

[HappyCamper]

Thanx for the replies!

How to spread the supplementation over the day? I've also added a few more supps to the basic stack. I'll compound custom capsules to be used. ** is only my father who is at risk for alz (runs in the family), user of swedish wet snuff since 50 years (extremely high doses of nicotine every day!)

Morning, with breakfast:

*EPA/DHA 600 mg/400 mg
*astaxanthin 4 mg
*vinpocetine 10 mg-20 mg
*multivitamin (ABC Plus Senior OR
Daily One Plus)
*protein shake (20-30 grams whey isolate, Volactive Whey 80)
*S-PS (phosphatidylserine) 200 mg (capsule 1)
*carnosine 500 mg (capsule 1)
*gingko biloba 120 mg (capsule 2)
*resveratrol 98% 250 mg (capsule 2)
*lechitine ~a spoonful
*choline bitartrate 500 mg (capsule 3)
*piracetam 700 mg (capsule 3)
*oxiracetam 300 mg (capsule 3)
**simvastatin 20 mg (statin, cholesterol lowering)
**lexapro 20 mg
**toprol (seloken, beta-blocker) 50 mg
**deprenyl 2,5 mg
**ibuprophen 200 mg

Midday:

*vinpocetine 10-20 mg
*choline bitartrate 500 mg (capsule 3)
*piracetam 700 mg (capsule 3)
*oxiracetam 300 mg (capsule 3)
*choline bitartrate 500 mg (capsule 3)
**hydergine 5 mg
**deprenyl 2,5 mg

Evening:

*EPA/DHA 600 mg/400 mg
*carnosine 500 mg (capsule 1)
*S-PS 200 mg (capsule 1)
*gingko biloba 120 mg (capsule 2)
*resveratrol 98 % 250 mg (capsule 2)
**ibuprophen 200 mg

Edited by HappyCamper, 21 January 2008 - 11:08 PM.

[balance]

Looks good. I'd take out the ibuprofen though...

I'd take the carnosine in a single 1000mg dose. Maybe replace the lecithin by r-dihydro-lipoic acid. The carnitine-lipoic acid combination has shown to be incredible candy for your brain, definitely worth adding/replacing in your regimen. Btw, for convenience, have you seen lef sells a ginkgo that has 120mg in 1 capsule. Also, keep in mind it's a strong blood thinner, especially at 240mg, and if you have the ibuprofen and fish oil in there too... might not be very safe in the long run, also keep in mind what about if he has an accident and goes in for immediate surgery in the hospital.. that is always something overlooked for when people take a lot of blood thinners, they know they're safe, but what about an unforeseen accident.

I'm a big fan of pomegranate for a while now, but DukeNukem has convinced me to keep it in my regimen. I'd recommend the same for your father. Inositol might aid with your choline requirements too btw. Might help you save some supplements (effort/convenience) and money.

Like niner said, put some vitamin d3 in there. Be sure to get it in softgels. 1000-2000IU up to 5000IU total intake from all supplements and diet should be good. Hopefully he will be open for getting some blood tests done just in case.

Edited by piet3r, 21 January 2008 - 11:24 PM.

[HappyCamper]

Changes as follow:

Morning
*r-ala 200 mg

Midday
*1000 mg carnosine (none evening and morning)
*200 mg r-ala

Ibuprophen is gambling, but it shouldn't be toxic to the kidneys even after prolonged use at those doses. There are very impressive studies indicating that use of NSAID medications (at least daily during two years) lowers the risk of getting alz quite a lot. Is d-vitamin in the form of ergocalciferol drops ok? Those are very cheap over here (Sweden) and one small bottle is like 250 000 I.U. My aim with the racetams is to find a good combo between pi, oxi, ani and pram. Supps are extremely expensive here, so the more esoteric ones (pram, res etc.) I import from China and (usually!) have a friend analyze for heavy metals and melting point (basic analysis) and sometimes with HPLC etc. BTW, I analyse them myself too sometimes, studying to become a pharmacist. The bloodthinning is a problem with acute surgery, so I'll make a small necklace saying "on bloodthinning meds" in the workshop tomorrow.

Edited by HappyCamper, 22 January 2008 - 01:04 AM.

[health_nutty]

Changes as follow:

Morning
*r-ala 200 mg

Midday
*1000 mg carnosine (none evening and morning)
*200 mg r-ala

Ibuprophen is gambling, but it shouldn't be toxic to the kidneys even after prolonged use at those doses. There are very impressive studies indicating that use of NSAID medications (at least daily during two years) lowers the risk of getting alz quite a lot. Is d-vitamin in the form of ergocalciferol drops ok? Those are very cheap over here (Sweden) and one small bottle is like 250 000 I.U. My aim with the racetams is to find a good combo between pi, oxi, ani and pram. Supps are extremely expensive here, so the more esoteric ones (pram, res etc.) I import from China and (usually!) have a friend analyze for heavy metals and melting point (basic analysis) and sometimes with HPLC etc. BTW, I analyse them myself too sometimes, studying to become a pharmacist. The bloodthinning is a problem with acute surgery, so I'll make a small necklace saying "on bloodthinning meds" in the workshop tomorrow.

I would replace the ibuprophen with baby aspirin. (and add turmeric).

[Christopher5]

Alzheimer's Supplements Table can be seen at
http://gaiahealth.net/Alzheimers.html

And

Vitamin C has been found to delay the progress of the disease. Orange juice has been effective in resolving the symptoms of Alzheimer like dementia.

Drink 250 ml of orange juice thrice daily for three months.There is a marked improvement in the symptoms of Alzheimer's disease in three months.

For more best natural treatment, http://***

(edited by Matthias: commercial link removed)

Edited by Matthias, 27 July 2008 - 08:52 AM.

[platypus]

Btw, for convenience, have you seen lef sells a ginkgo that has 120mg in 1 capsule. Also, keep in mind it's a strong blood thinner, especially at 240mg, and if you have the ibuprofen and fish oil in there too... might not be very safe in the long run, also keep in mind what about if he has an accident and goes in for immediate surgery in the hospital.. that is always something overlooked for when people take a lot of blood thinners, they know they're safe, but what about an unforeseen accident.

Is this really a concern? I take 240mg of Ginkgo, fish oil, E-vitamins and other blood thinners. What would be the symptoms of a long-term problem? I do bruise quite easily but if I get cut the wound closes normally.

Edited by platypus, 30 January 2008 - 01:00 PM.

[health_nutty]

Btw, for convenience, have you seen lef sells a ginkgo that has 120mg in 1 capsule. Also, keep in mind it's a strong blood thinner, especially at 240mg, and if you have the ibuprofen and fish oil in there too... might not be very safe in the long run, also keep in mind what about if he has an accident and goes in for immediate surgery in the hospital.. that is always something overlooked for when people take a lot of blood thinners, they know they're safe, but what about an unforeseen accident.

Is this really a concern? I take 240mg of Ginkgo, fish oil, E-vitamins and other blood thinners. What would be the symptoms of a long-term problem? I do bruise quite easily but if I get cut the would closes normally.

Based on the medical advice of doctors giving patients aspirin therapy you should look for more than normal bleeding from minor cuts (such as when flossing or when shaving).

[balance]

I noticed problems with the veins on my feet when I was taking 240mg of ginkgo + fish oil + vitamin E. I was taking vitamin K all that time but the thinning was too strong.. I cut down and the problems went away. Look for things like spider/varicose veins or abnormally large veins etc etc.

[outsider]

For alzheimer, definitely turmeric and green tea.

Edited by outsider, 16 February 2008 - 05:39 AM.