I've been taking 100mg to 500mg resveratrol daily since early 2005. Since that time I've suffered from mild sensory neuropathy in my shoulders, thumbs, index fingers, and pinkies. The effect is more pronounced on my left (non-dominant) side.
Because I was recovering from a neurological procedure on my lumbar spine when I began supplementation, I suspected some kind of low-grade tethered cord syndrome as the cause of my upper-body sensory neuropathy. However, recently I've begun to suspect resveratrol as the cause through process of elimination.
I wonder how many other resveratrol-takers suffer from these symptoms. Because sensory neuropathy is rare among non-diabetics, and unscientific survey in this forum would be helpful to me. I'd also like to invite speculation as to the specific mechanisms that might be involved here. If resveratrol does indeed induce a starvation-stress-response in the body, I could imagine an inhibitory effect on the growth of new (and expensive) peripheral neurons even while increasing the durablity of existing neurons. However, I'm not at all familiar with how the peripheral nervous system maintains itself.