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Supplements for allergies + asthma


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#1 nameless

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Posted 27 March 2008 - 05:33 PM


Hello,

With spring arriving here, that also means allergy season is starting for me. What are some good supplements for those of us with allergies? Also, what can be used to help with asthma too?

I'm currently taking Flovent and Accolate for asthma, along with Nasalcrom for allergies, but I'd like to cut down on these medications if possible. When my nose is real bad, I'll also take an antihistamine.

I've read that these might help:

Quercetin
Rutin
Vitamin C
Pycnogenol and/or grape seed

Any others? And of the above, do any hold health risks that I am unaware of, or interact with any medications? I've tried pycnogenol as well as grape seed extract, and I can't say I have really noticed any benefit for allergies or asthma -- then again, they may be helping and I'm not aware of it. Perhaps my nose would explode if I weren't taking them.

Edited by nameless, 27 March 2008 - 05:34 PM.


#2 krillin

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Posted 28 March 2008 - 02:42 AM

Have you tried citrus bioflavonoids? (They probably include naringin, so grapefruit drug interactions would apply.) Someone reported that Epicor works too.

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#3 Jacovis

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Posted 28 March 2008 - 08:21 AM

From a thread I started a number of weeks back...


http://www.imminst.o...mp;#entry223353
Yakriton (Bovine liver fat extract), Apparently acts as a natural anti-histamine and liver decongesent

This substance was discovered in the 1920s by the Japanese. I could find little research on it on the internet.
It is included in two formulas from Standard Process Supplements: Antronex and Allerplex.

http://www.becomehea.../antronex.shtml
Contains 15 mg of Yakriton per tablet - An uncommon bovine liver fat extract that has been shown to he maintain a healthy liver. One of its most valuable uses lies in its blood filtering capabilities*

http://www.becomehea...allerplex.shtml
Contains Yakriton An uncommon bovine liver fat extract that has been shown to help maintain a healthy liver through it's ability to aid in filtering blood*


http://www.amazon.co...s/dp/B0006IIDKU
5/5 stars
Dog with Cushings uses These, January 4, 2007
By Claire Stokes "Rev Claire Stokes" (CA, USA) - See all my reviews

"This helps open up the hepatic flow ( blood flow through your liver) and my dog takes this in her food everyday. great product , love standard process the whole thing really works.your body will heal itself if you take the right products for the condition. very happy with this."


http://www.revolutio...ural-home/92482
"Standard Process makes whole food supplements. Natural, organic. I have completely handled my asthma with their product Antronex. But you have to find a chiro, naturopathic doctor, acupuncturist or other health practitioner ("HCP") that carries Standard Process Labs. Actually, I use 2 products: Antronex and Emphaplex, but a good HCP can test to see which your son's body responds to, and how much/how often. It eliminates the need for all those Allopurinol, Tedral, etc. that are speed-based and even phenobarbitol based. When I was growing up, I hated the medicine -- I never knew if it would put me to sleep or make me uncontrollably nervous.

Also, your son's adrenals are probably stressed. Get him off all sugar and white flour. For sweetener, use Stevia or Grade B maple syrup. Use whole grains. He might even have a wheat sensitivity (like Celiac's disease), so try giving him brown rice pastas and breads. But the sugar is devastating to an asthmatic, especially during asthma attacks. (For me, that was worst during the cold, damp autumns of New England.)

Lots of protein and raw vegetables are helpful. Sometimes chewing natural bees' honey (with the hive) can be helpful, but not everyone responds to this. (It didn't help me at all but I've heard of others who had success with this.)

I am not a doctor or HCP, so I'm only giving you the benefit of my experience.

Hope it helps. Lynn in Glendale, CA."
--
0 Ratings & reviews
Sign in to rate Posted 11:54AM (EDT) on 2007-06-24 by lynn91208


http://www.chiropub..../2008-02_07.asp
"Nutrients to Reduce Histamine Levels
A natural antihistamine product that works well is Antronex by Standard Process. It is also important to consider the histamine metabolizing agents, which are folic acid, spleen glandular, quercetin, B6, pyridoxal-5-phosphate, betaine, etc. These can be obtained from Thorne, Nutri-West, or Metagenics."


http://p207.ezboard....picID=595.topic
rezjet (April 26, 2005):
"I am have been taking a generic Atarax (25 mg) for several months, 1/2 or 1 nightly. It helps me sleep and reduces the itching significantly. During the day, I also take a natural supplement from my Naturopath that has impacted me more successfully than Atarax. This product is called Antronex
(An-tro-nex) by Standard Process Inc. I take 2 tablets, 3x daily with meals. and the itching by day is reduced by 75%. The last 2 alternative specialists only use this company because of the company's longtime experience and success with natural products. My original itchy red bumps are smaller, much lighter in color and far less itchy! My skin is no longer bruised looking from night scratching. My recipe for improved success the last 4 months includes a nutritional plan called, Eat Right for your Blood Type (B), a few specific supplements, visits to the naturopath, exercise, lots of water, warm baths, and prayer... I am much healthier and happier... As Tanya mentioned, they are much improved from the active lesions. Good luck,"


http://answers.yahoo...07163809AAYkflX
Shelly:
"Forget the oak theory. You are wrong. Start with getting your dog scraped to rule out mites. After that, change your dogs food. What you are feeding is NOT working. You need a good kibble (NOT canned) or dehydrated or frozen or raw. If you choose any commercial product, you'll have to supplement with pro-biotics, digestive enzymes, & kelp. The antihystamine that is super effective is called Antronex made by Standard Process. NO treats for a while until you get ahead of this."


http://forum.america...i...106&start=0
Karen_P (September 13, 2007):
"There's an all-natural supplement called Antronex made by Standard Process. It's made with Bovine Liver Extract and helps to flush the body of toxins and histamine.

I've been really successful treating my dog's seasonal allergies with it. I bought it through a holistic vet the first time, and then ordered it online. Here's a link:

[url="http://www.naturamart.com/standard-process...lets.html""]http://www.naturamart.com/standard-process...lets.html"[/url]


http://www.askshelle.......&highlight=
J F (May 31, 2006):
"I see a naturopathic doctor who has used [Antronex] with success for her patients who have bad food allergies. She recommends that people take it if they feel they've had a food related allergy attack, the way you'd take Benadryl if you were allergic to something and accidentally took it. I am sure she would recommend it for other things as well, but that particular purpose was why she brought it up to me in conversation, once. I have not used it myself, but I can say it is recommended by at least one good doctor I know."


http://www.medhelp.o...sts/show/339917
by AmyRW70, Jan 12, 2008 02:25AM
To: frenchgirl314 & Ronni909

"I too have this very problem - itching throat w/ chronic cough & sneezing. It has been ongoing when I don't take the following: The one thing that has worked for me is taking Standard Process "Antronex", which helps maintain a healthy liver via its blood filtering and affect on histamine & "Allerplex", the body' s natural cleansing system.(http://www.becomehea...rint.php?id=115) The approach in treating allergies in a natural sense is to repair those body systems which are not meeting the demands of the invading allergen. You can buy these at Amazon.com. I take up to 18 Antronex a day & 4 Allerplex (remember, it's whole food so less potent)..."

#4 Matt

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Posted 28 March 2008 - 08:47 AM

Probably not what you want to here... but Calorie Restriction and a generally healthy diet *cured* my hay fever... I had it severely too.

You can try

Quercetin
Green Tea
Omega 3
Resveratrol

Those should help a lot...

#5 tintinet

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Posted 28 March 2008 - 02:41 PM

Also

Bee Pollen

Butterbur

#6 nameless

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Posted 29 March 2008 - 12:23 AM

Thanks for the suggestions everyone. I'll have to do a little research on the supplements recommended.

Citrus bioflavonoids -- I've tried them in relatively small doses in the past (whatever is included with Ester C, I think 200mg). I didn't notice any major benefit, but the dose may have been too small. The grapefruit issue is something I probably need to be careful about, because I am taking several prescription medications now. There is a small amount of grapefruit currently in my AOR Multi, but according to AOR, the grapefruit content is far too small to cause any problems. Maybe if I can find a bioflavanoid supplement without grapefruit, it'd be worth a shot.

Epicor -- I've read anecdotal comments that it helps with allergies in some people, but I'm not aware of any studies to back it up. Immune modulation could play a role with allergies, so at least there is possibly some science behind it. I'd feel better if the Epicor studies were a bit more, well, more.... and the data more persuasive.

Bovine liver fat extract -- probably will pass on this. A bit too obscure and it doesn't exactly sound appealing to consume.

Butterbur/Bee pollen -- I'll have to do more research on it, especially regarding if it can cause any drug interactions and/or side effects.

Quercetin + Bromelain appears to be something that helps, according to user reports of the supplements, anyway. But are there SIRT1 issues with quercetin (read somewhere that metabolites of quercetin inhibit SIRT1 activity)? There was also that mouse study that showed quercetin reducing their lifespan. Not good to improve allergies, then end up dying sooner.

Calorie restriction + diet -- I'm not doing caloric restriction, but my diet is relatively decent. I am taking plenty of Omega 3's and a tiny amount of resveratrol (in my grape extract). I am waiting for some human studies before jumping on the resveratrol bandwagon. Green tea seems to give me occasional stomach problems, and in the past I tried to force myself to drink it daily, but I really don't like how it tastes. Currently drinking rooibos though.

I'll look into bioflavanoids + immune modulation, for now, and maybe quercetin and/or butterbur.

#7 tham

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Posted 31 March 2008 - 04:20 PM

A good candidate is black seed, or Nigella sativa.
The oil appears to be the preferred form.

http://www.kitchendo...blackcumin.html

http://www.amazinghe...tisblacse1.html

http://www.barakaoil.com/


http://www.ncbi.nlm....l=pubmed_docsum

http://www.ncbi.nlm....l=pubmed_docsum

http://www.ncbi.nlm....l=pubmed_docsum

http://www.ncbi.nlm....l=pubmed_docsum


Its component, thymoquinone, is a cancer fighter.

http://www.ncbi.nlm....l=pubmed_docsum

http://www.ncbi.nlm....l=pubmed_docsum

http://www.ncbi.nlm....l=pubmed_docsum

http://www.ncbi.nlm....l=pubmed_docsum

http://www.ncbi.nlm....l=pubmed_docsum

http://www.ncbi.nlm....l=pubmed_docsum

http://www.ncbi.nlm....l=pubmed_docsum

http://www.ncbi.nlm....l=pubmed_docsum

http://www.ncbi.nlm....l=pubmed_docsum

http://www.ncbi.nlm....l=pubmed_docsum

http://www.ncbi.nlm....l=pubmed_docsum


I take this for general support every now and then. Seems this
Egyptian manufacturer has a factory in Romania too. Quite cheap
over here in Malaysia, at M$8 for 30 softgels, 450 mg.

http://www.magazine-...---pharco--3189

Edited by tham, 31 March 2008 - 05:00 PM.


#8

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Posted 31 March 2008 - 06:04 PM

Some people find that either taurine or cysteine help with allergies. NAC has mucolytic properties (thins out mucous). NAC especially helps with gluthionine levels so you may want to make sure you have the other nutrients needed for gluthionine.

#9 tham

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Posted 01 April 2008 - 08:58 AM

Instead of Flovent (fluticasone), you may want to ask
your doctor about the third-generation inhaled steroid,
ciclesonide (Alvesco).

It was developed by the German drug firm Altana, formerly BYK.

It had three advantages over fluticasone, with the third
the most important :

Once daily dosing

Low incidence of oral thrush, since it is a prodrug
and is not active in the throat

Very low systemic absorption of just 1% (compared to
10% for the second-generation fluticasone and as high
as 25 % for the older first-generation inhaled steroids,
budesonide and beclomethasone diproprionate)


http://www.alvesco.c...InFrontpage.htm

http://www.nycomed.c...CACHEHINT=Guest


http://www.medscape....warticle/549745

http://www.fmshk.org...eviewdrwong.pdf

http://www.ncbi.nlm....l=pubmed_docsum

http://cat.inist.fr/...cpsidt=17747500

http://www.ncbi.nlm....l=pubmed_docsum

http://www.ncbi.nlm....l=pubmed_docsum

http://www.ncbi.nlm....l=pubmed_docsum

http://www.ncbi.nlm....l=pubmed_docsum

http://www.ncbi.nlm....l=pubmed_docsum

http://www.ncbi.nlm....l=pubmed_docsum

http://www.ncbi.nlm....l=pubmed_docsum

http://www.ncbi.nlm....l=pubmed_docsum

#10 nameless

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Posted 01 April 2008 - 06:08 PM

Instead of Flovent (fluticasone), you may want to ask
your doctor about the third-generation inhaled steroid,
ciclesonide (Alvesco).


Ooh... thanks for that info. Unfortunately it's not out yet in the US, but should be later this year. I'll ask my doc about it.

One side effect I dislike about Flovent is that is sometimes makes my throat a little irritated -- maybe Alvesco would help with that.

#11 tham

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Posted 02 April 2008 - 04:18 PM

Alvesco has just been released in the US market.

Nycomed, formerly Altana Inc, is the distributor
in your area.

http://www.medicalne...icles/94632.php


You could try contacting them.

Nycomed US Inc
60 Baylis Road
P.O. Box 2006
NY 11747
Melville
Paul McGarty
(631) 454 76 77

#12 nameless

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Posted 02 April 2008 - 04:53 PM

Alvesco has just been released in the US market.

Nycomed, formerly Altana Inc, is the distributor
in your area.

http://www.medicalne...icles/94632.php


It's been FDA approved, but not released yet as a product here (so far as I know). Sepracor appears to be the ones going to sell it, as they have a commercialization agreement with Nycomed. Hopefully it'll start showing up within the next couple of months or so.

#13 Jacovis

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Posted 26 May 2008 - 11:01 AM

1: Int Arch Allergy Immunol. 2008 Mar 26;146(4):298-306. [Epub ahead of print]

Colostrinin Decreases Hypersensitivity and Allergic Responses to Common Allergens.
Boldogh I, Aguilera-Aguirre L, Bacsi A, Choudhury BK, Saavedra-Molina A, Kruzel M.
Departments of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Tex., USA.

Background: Colostrinintrade mark (CLN), isolated from mothers' pre-milk fluid (colostrum), is a uniform mixture of low-molecular-weight, proline-rich polypeptides. CLN induces neurite outgrowth of pheochromocytoma cells, extends the lifespan of diploid fibroblast cells, inhibits beta-amyloid-induced apoptosis and improves cognitive functions when administered to Alzheimer's disease patients. Objective: The aim of this study was to investigate potential allergic responses to CLN and its impact on allergic sensitization and inflammation caused by common allergens. Methods: We used a well-characterized mouse model of allergic airway inflammation. Changes in IgE/IgG1 and mucin levels, airway eosinophilia and hyperreactivity to methacholine were determined by ELISA, differential cell counting and whole-body plethysmography, respectively. Results: CLN did not increase IgE/IgG1 levels or induce cutaneous hypersensitivity reaction, airway inflammation and mucin production. Importantly, CLN significantly (p < 0.001) decreased IgE/IgG1 production, airway eosinophilia, mucin production and hypersensitivity induced by allergenic extracts from ragweed pollen grains and house dust mites. Conclusion: CLN itself is non-allergenic; however, it is effective in preventing allergic responses to known indoor and outdoor allergens. These data support the safe application of CLN and its potential use in the prevention of allergic inflammation in humans. Copyright © 2008 S. Karger AG, Basel.

PMID: 18367843 [PubMed - as supplied by publisher]

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#14 Lufega

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Posted 28 September 2009 - 02:04 PM

Relationship among manganese, arginase, and nitric oxide in childhood asthma.

Kocyigit A, Zeyrek D, Keles H, Koylu A.
Department of Biochemistry, Medical Faculty, Harran University, 63200 Sanliurfa, Turkey.

It has been demonstrated that the lowest intakes of manganese (Mn) were associated with more than a fivefold increased risk of bronchial reactivity. It was also known that nitric oxide (NO) production was found to be significantly higher in asthmatics. There is a reciprocal pathway between arginase and nitric oxide synthase (NOS) for NO production, and Mn is required for arginase activity and stability. We investigated plasma NO, arginase, and its cofactor Mn levels to evaluate this reciprocal pathway in patients with childhood asthma. Arginase activities and Mn and NO levels were measured in plasma from 31 patients with childhood asthma and 22 healthy control subjects. Plasma arginase activities and Mn concentrations were found to be significantly lower and NO levels were significantly higher in patients with childhood asthma as compared to the control subjects. There was a significantly positive correlation between plasma Mn and arginase and negative correlations between arginase and NO values and Mn and NO values in patients with childhood asthma. These data indicate that the lower concentration of Mn could cause lower arginase activity and this could also upregulate NO production by increasing l-arginine content in patients with childhood asthma.






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