Cannabis for longevity?
abolitionist 08 Jan 2013
"Myth : Cannabis causes sterility and lowers Testosterone"
Edited by abolitionist, 08 January 2013 - 12:41 AM.
lifebuddy 08 Jan 2013
Other than that, cannabis is a great drug with far fewer negative effects on health than alcohol. For the general (read: unhealthy) population, replacing excessive alcohol consumption with excessive cannabis consumption will probably extend your life by eliminating many of the negatives associated with alcohol. So yes, in many ways, cannabis can extend the life of the average person
abolitionist 08 Jan 2013
I would guess that eating cannabis raw including the buds, seeds, and leaves would be the best way to obtain solely the longevity benefits {thereby not creating THC and not getting high}
Heating up the cannabinoids to create THC might have a detrimental effect on the protective effects as a whole.
Raw Cannabis concentrates may become an equal supplement [in terms of sales] to Resveratrol in the now legalized states {USA}
Edited by abolitionist, 08 January 2013 - 12:53 AM.
lifebuddy 08 Jan 2013
I wouldn't want to make a bet at this point myself, but it's an interesting theory.
I would guess that eating cannabis raw including the buds and leaves would be the best way to obtain solely the longevity benefits {thereby not creating THC and not getting high}
Heating up the cannabinoids to create THC might have a detrimental effect of the protective effects as a whole.
THC is already present. Heating cannabis does not create THC. Cannabis is often heated in conjunction with a fat, thus allowing the cannabinoids to bind to fats and thus be significantly more absorbable in the gut.
abolitionist 08 Jan 2013
kevinseven11 08 Jan 2013
Adaptogen 09 Jan 2013
I also notice similar, uncomfortable bodily sensations when supplementing with resveratrol.
My speculation is that these sensations are sometimes uncomfortable because I already have very low levels of inflammation as a result of lifestyle/ low bmi (19.4).
Does any of this sound plausible?
anagram 10 Jan 2013
Cannabis "slows metabolism.." well l-histidine does the same thing, by making hydrogen peroxide so damaging to DNA, that a shit load of Double strand breaks occur, which on its own, Hydrogen peroxide isn't even capable of doing.
http://www.ncbi.nlm..../pubmed/1588927
and we eat this all the time...
-moral of the story is don't use cannabis that often, or at all if you aren't old enough to.
and just so you don't go on an anti-Histidine rampage-
http://www.ncbi.nlm....pubmed/19782114
http://www.ncbi.nlm....pubmed/22011298
http://www.ncbi.nlm....pubmed/16530908
http://www.ncbi.nlm....pubmed/12624476
l-Histidine acts as an antioxidant when bound to metals like zinc(the complex is called curazink(German name I think),
and apparently zinc also increases the antioxidant efficacy of Carnosine(from last page on lef webpage on Carnosine).
Edited by anagram, 10 January 2013 - 03:21 AM.
lifebuddy 10 Jan 2013
I have friends who smoke pot, and the damage is slowly becoming apparent. they sometimes have little moments while I am talking to them where they look like they are about to pass out, but they soon return to normality after milliseconds, it looks like some sort of sesiure, and they only smoke about an eighth to two eighths a week.
I know that cannabis is not good for you
It is much more complex than that. Cannabis is like a mother to millions upon millions around the world. It is their spirit guide. Their plant ally. It warms them at night and soothes their troubled souls in the day, without lying to them like alcohol, stimulants, and other people. It allows them to be at peace with themselves and the universe. For some people, marijuana allows them to live with themselves, and to deal with a troubled past. My wife is a prime example. Without marijuana (and she has gone many months without), she begins to think herself into a mental breakdown. She is consumed with thoughts of her past, confused about the present, and worried about the future. With marijuana, she lives like a 'normal' human being.
You say your friends are slowly being damaged. Have you ever met anyone who has become completely debilitated from their use of marijuana? People whose minds simply don't work? Who you can't talk to because their sort of seizures have gotten so bad that they are catatonic? Talking anecdotally... Living in the bay area, I have met dozens of well aged lifetime pot-heads (multiple daily smokers) who don't appear to be any worse off than the rest of joe public.
It is also easy to observe what seems to be negative impressions of the stoned youth. But don't forget that many many people are inherently lazy anyway. They play computer games with or without pot. They don't exercise with or without pot. Nor do they eat well or study well.
anagram 10 Jan 2013
If your wife is getting a positive effect from Marjiana, does she get a positive effect from any other supplements?
Edited by anagram, 10 January 2013 - 09:34 PM.
YOLF 11 Jan 2013
http://www.ncbi.nlm....les/PMC1253627/ ;
"Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects"
... but leads to diminished testosterone with time and thus more risk factors for depression in men. The mayoclinic IIRC also has info stating that contrary to popular belief, THC can be bad for the developing fetus, and breast feeding concentrations are many times higher (and still decarboxylated) than in the woman's blood. So any embryonic benefit is likely not worth the risk. As ingestion results in much longer and more dramatic effects, I'd say baby is pretty damn wasted! Excess, even in adults has shown very bad indirect side effects. I think it may only be acceptable for women to use it when they aren't pregnant or at risk of becoming so.
YOLF 11 Jan 2013
http://norml.org/lib...th-mythology#13
"Myth : Cannabis causes sterility and lowers Testosterone"
If pot can suppress T temporarily, and is used long enough to cause weight gain, T get's diminished until the weight is lost. What are the damages of having diminished T for any period of time? I will agree that in the past bad science has been propagandized, but now we're seeing the same thing from the opposite end of the prohibition argument. Pot studies have to be taken with a grain of salt. There are also studies which show that it can cause metabolic syndrome.
YOLF 11 Jan 2013
I think the forced relaxation is good for the body, as long as it isn't used all day long. Used effectively, it can increase your positive outlook on things and allow time for self-reflection (and therefore self-improvement). It has to be used in a very specific way though.
Other than that, cannabis is a great drug with far fewer negative effects on health than alcohol. For the general (read: unhealthy) population, replacing excessive alcohol consumption with excessive cannabis consumption will probably extend your life by eliminating many of the negatives associated with alcohol. So yes, in many ways, cannabis can extend the life of the average person
Correction: ...cannabis can extend the life of the average "alcoholic"
While pot may have some benefits, I think I'll wait until after I'm immortal and medicine can reverse any negative effects of smoking it. Actually I think I'd prefer a safe future synthetic that raises T and gives me tons of stimulant energy to go with the good feelings.
I tried pot once overseas, but it causes an over production or more efficient recycling of a neuro hormone that makes you relaxed and gives you a feel good attitude. Tried the hormone too, it was more effective (greater sense of relaxation and emotional wellbeing), less (hardly)debilitating, and doesn't result in compromised thought processes. I will admit that it probably isn't as safe as pot as far as overdoses and side effects go as the hormone widely dispersed to other systems. It's also legal and won't get you arrested.
YOLF 11 Jan 2013
Thc doesnt effect hormone levels much but it does inhibit dht binding to the androgen receptor according to two vitro studies. The smoke from cannabis has a chemical that prevents testosterone from metabolizing into estrogen thus counteracting the whole effect.
So how do they have evidence for suppressing T? How is it data from human samples shows suppressed levels and lower sperm counts, even though temporary, but somehow raises T? I think something's missing. Perhaps more Free T, but less available to use T. The difference being that one has been partially metabolized and is waiting to be recycled.
YOLF 11 Jan 2013
Indica varieties have alot more CBD which can cause headaches and other bodily pains. Sativa varieties are used for pain relief and contain virtually no CBD. CBD, IIRC causes inflamation, but its effects are usually dwarfed by the THC. It's possible you got a bad harvest. I've also read that fungi that grow on the stuff can have toxins, perhaps these are causing your discomfort? I also read somewhere that THC can be made synthetically and it sounds safer than pot that could have any kind of crap in it. there is also the possibility that an amateur farmer used a strong fertilizer that isn't meant to feed plants for human consumption but results in vigorous growth.When i smoke a decent amount of potent marijuana, particularly a strain with a high proportion of cannabinoids/thc ratio (indica), I notice strong, almost unpleasant bodily sensations. I think these are from the anti-inflammatory effects of cannabis.
I also notice similar, uncomfortable bodily sensations when supplementing with resveratrol.
My speculation is that these sensations are sometimes uncomfortable because I already have very low levels of inflammation as a result of lifestyle/ low bmi (19.4).
Does any of this sound plausible?
Maybe Saffron would be a better way to go...
I've heard good things about saffron, though I haven't tried it, I have bulbs for it though.
YOLF 11 Jan 2013
I have friends who smoke pot, and the damage is slowly becoming apparent. they sometimes have little moments while I am talking to them where they look like they are about to pass out, but they soon return to normality after milliseconds, it looks like some sort of sesiure, and they only smoke about an eighth to two eighths a week.
I know that cannabis is not good for you
It is much more complex than that. Cannabis is like a mother to millions upon millions around the world. It is their spirit guide. Their plant ally. It warms them at night and soothes their troubled souls in the day, without lying to them like alcohol, stimulants, and other people. It allows them to be at peace with themselves and the universe. For some people, marijuana allows them to live with themselves, and to deal with a troubled past. My wife is a prime example. Without marijuana (and she has gone many months without), she begins to think herself into a mental breakdown. She is consumed with thoughts of her past, confused about the present, and worried about the future. With marijuana, she lives like a 'normal' human being.
You say your friends are slowly being damaged. Have you ever met anyone who has become completely debilitated from their use of marijuana? People whose minds simply don't work? Who you can't talk to because their sort of seizures have gotten so bad that they are catatonic? Talking anecdotally... Living in the bay area, I have met dozens of well aged lifetime pot-heads (multiple daily smokers) who don't appear to be any worse off than the rest of joe public.
It is also easy to observe what seems to be negative impressions of the stoned youth. But don't forget that many many people are inherently lazy anyway. They play computer games with or without pot. They don't exercise with or without pot. Nor do they eat well or study well.
There is and probably has always been a reason for calling it "getting stoned."
YOLF 11 Jan 2013
????
Hmmm... it was years ago, but I had come across a site with detailed instructions from the marinol patent on how to make marinol. It yeilded 5 canibinoids including primarily THC and no CBD making it superior as a pain reliever. IIRC the site was very simple and had a cloudy blue background or a blue background with white dabs on it. The patent was owned by in Israeli company I think.
Or were you asking about a different post?
abolitionist 11 Jan 2013
but from a pure longevity perspective - even over consumption could lead to longer lifespan due to;
1. slower metabolism
2. lower body heat
3. protection against free radicals
4. cancer provention
5. lowering of stress hormones
6. neuroprotection
7. anti-inflammatory
so even if you overconsume and make yourself retarded you may live longer (all things being equal)
If one could maintain a healthy lifestyle while using cannabis I think the overall effect would be beneficial in terms of longevity.
Also eating the leaves and ground seeds is a good idea from a health perspective.
Edited by abolitionist, 11 January 2013 - 06:00 PM.
YOLF 11 Jan 2013
abolitionist 11 Jan 2013
you're just playing it safe in terms of societal acceptance IMO
Edited by abolitionist, 11 January 2013 - 08:22 PM.
YOLF 11 Jan 2013
abolitionist 11 Jan 2013
there's no link between pot use and believing in false solutions
those are gross generalizations
Edited by abolitionist, 11 January 2013 - 09:42 PM.
YOLF 11 Jan 2013
joelcairo 12 Jan 2013
anagram 12 Jan 2013
you might be fucking your mito's up every time you light up...
http://www.ncbi.nlm....pubmed/16414979
in addition, there are literally zero studies showing it has a positive effect on lifespan despite people smoking, and studying cannabis for thousands of years.
marijuana
1. makes you a little insane, cannot enjoy life properly
2. the fear
3. kills the money you could spend on ntBHA or some other supplement if you want greater lifespan
4. may lead to some form of mental illness depending on frequency of use and such
no fun...
Edited by anagram, 12 January 2013 - 02:32 AM.
abolitionist 12 Jan 2013
I read that article but it will take some learning to understand it completely. I'm not sure that the reasons for the alteration of the mitochondrial function were fully understood from that study.
... and it may be possible (I'm playing devil's advocate) that the alteration of mitochondrial function has a protective effect
Will be interesting to see scientific studies. There is good reason to investigate the possible benefits beyond pure science.
Edited by abolitionist, 12 January 2013 - 07:25 AM.
nupi 12 Jan 2013
marijuana
1. makes you a little insane, cannot enjoy life properly
2. the fear
3. kills the money you could spend on ntBHA or some other supplement if you want greater lifespan
4. may lead to some form of mental illness depending on frequency of use and such
Or high CBD strains just might cure anxiety disorders...
People are going to use drugs anyway and as far as they go, Cannabis has a pretty decent side effect profile. Claiming it is longevity enhancing is however probably a bit too much
abolitionist 12 Jan 2013
Cannabis is a big plant with many components - if smoking the buds can cause paranoia and make you lazy doesn't mean that cannabis itself has no potential value in the pursuit of longevity
Edited by abolitionist, 12 January 2013 - 10:11 AM.