How Cranberry Juice Prevents Urinary Tract Infections
The study, published in the journal Colloids and Surfaces: B, was conducted by Terri Camesano, associate professor of chemical engineering at WPI, and a team of graduate students, including PhD candidate Yatao Liu. They exposed two varieties of E. coli bacteria, one with hair-like projections known as fimbriae and one without, to different concentrations of cranberry juice. Fimbriae are present on a number of virulent bacteria, including those that cause urinary tract infections, and are believed to be used by bacteria to form strong bonds with cells.
For the fimbriaed bacteria, they found that even at low concentrations, cranberry juice altered two properties that serve as indicators of the ability of bacteria to attach to cells. The first factor is called Gibbs free energy of attachment, which is a measure of the amount of energy that must be expended before a bacterium can attach to a cell. Without cranberry juice, this value was a negative number, indicating that energy would be released and attachment was highly likely. With cranberry juice the number was positive and it grew steadily as the concentration of juice increased, making attachment to urinary tract cells increasingly unlikely.
Surface free energy also rose, suggesting that the presence of cranberry juice creates an energy barrier that repels the bacteria
So they exposed the culprit bacteria to cranberry juice. Isn't the situation in the human body a little different? Hasn't much of the juice's contents been altered or absorbed by the time they reach the urinary tract? This news seems good and all, but I am slightly skeptical as to the actual mechanism.
