Anyone ever try this noot? Does it really have a stimulant-type effect ?
Picamilone; alert and calm
What can be added to this combination of improved attention and awareness? If there is a need for a small boost of stimulation to awaken alertness and enthusiasm then picamilone could be useful.
Picamilone is a combination of niacin (vitamin B3) and GABA, but it is not just the two thrown into a capsule, rather it is actually bonded chemically to create a unique molecule.
In Russian studies picamilone has been shown to enhance interest in one’s surroundings and stimulate an interest in mental activity (e.g. wanting to think/ work), but at the same time it also keeps the individual calm and controlled. This could be the combination of what we would expect from both niacin and GABA individually, although under normal conditions taking both niacin and GABA together “as is” would be relatively ineffective in this regard, so picamilone does contain properties unique to its formula.
Some of the effects of picamilone have been attributed to its ability to easily cross the blood-brain barrier and stimulate blood circulation, (known as vasodilation) and in this respect it has been noted that it is more effective than hydergine or even vinpocetine.
A dose of 50 mg once or twice daily is normally sufficient for most individuals, particularly when combining it in a synergy program such as the one mentioned here.