7 replies to this topic

[edward]

I searched to see if someone had started a topic on this and apparently they hadn't, unless its hiding somewhere.

Anyways this stuff is like something out of an endurance athlete's wildest dream.

44% improvement in endurance over controls with no training, 70% improvement over controls with training. Converts muscle fibers to lean mean fat burning machines (might not be so great if you were trying to build fast twitch muscle fiber, but then again I'd rather have the biology of a world class endurance athlete with half the effort than a third class strength athlete working twice as hard)

http://www.latimes.c...0,4249687.story

insulin sensitization
http://www.sciencedi...46a5f1545367f84

http://www.webmd.com...in-a-pill-maybe

It is insanely expensive right now as it is only marketed toward researchers at "rat dosages".

[Shepard]

I'd be ridiculously surprised if it worked in humans. Try some metformin for the AMPK activation, or go low-carb, or try various popular supplements that might play around with AMPK in various tissues.

[edward]

Yes it does seem too "good" to be true and such things, with extreme biological effects, often don't translate from rats to humans.

Ehhh... metformin has some problems, testosterone lowering effect, increase in circulating TNF-alpha, gastrointestinal side effects. Low carb, of course, I live in low carb land, but I am an American after all with that inborn desire to solve everything with a pill

[Shepard]

Ehhh... metformin has some problems, testosterone lowering effect, increase in circulating TNF-alpha, gastrointestinal side effects.

Finally, someone that agrees with me.

Although, a couple of our members didn't seem to have any trouble with testosterone or SHBG from metformin when I asked them.

[neogenic]

I searched to see if someone had started a topic on this and apparently they hadn't, unless its hiding somewhere.

Anyways this stuff is like something out of an endurance athlete's wildest dream.

44% improvement in endurance over controls with no training, 70% improvement over controls with training. Converts muscle fibers to lean mean fat burning machines (might not be so great if you were trying to build fast twitch muscle fiber, but then again I'd rather have the biology of a world class endurance athlete with half the effort than a third class strength athlete working twice as hard)

http://www.latimes.c...0,4249687.story

insulin sensitization
http://www.sciencedi...46a5f1545367f84

http://www.webmd.com...in-a-pill-maybe

It is insanely expensive right now as it is only marketed toward researchers at "rat dosages".

There is a whole thread on this, not in this section. I've looked the research on AICAR for 3 years now, prior to even these studies...I used to wonder if there was any potential in humans until this batch of studies came out. I too have looked for the chemical and the prices are insanity...though cheaper than they were a few years ago from the chem. houses. There's a number of compounds I thought about exploitng in this pathway actually and some supplements I am designing are along this train of thought.

http://www.imminst.o...o...c=23495&hl=

[edward]

Thanks for pointing out that other thread, I think the search function was having issues when I looked for it before, anyway its a good topic for the supplements section

[neogenic]

Thanks for pointing out that other thread, I think the search function was having issues when I looked for it before, anyway its a good topic for the supplements section

Agreed. I searched here originally and started a thread on it. My thread got collapsed in to that one. I rarely stray outside of the supplements forum. And we all know how effective the search is here. I wish that could be fixed. There'd be so much more posting and better threads if it was. There'd be less of the "top 10 supplement" threads and whatever started over and over. You can't criticize anyone about not searching...it just is nearly useless.

[Mind]

We will be working on the search function.

Also, if you go to "more search options" and then use combinations of words (Example: "+nanotech +cancer") along with a member name, you will get better results, not great but better.