11 replies to this topic

[unbreakable]

Is anybody here taking many supplements, herbs AND synthetic antidepressants like SSRIs/SNRIs/Bupropion? Many herbs can inhibit MAO to some degree and supplements like SAM-e affect neurotransmitters too.

[luv2increase]

Is anybody here taking many supplements, herbs AND synthetic antidepressants like SSRIs/SNRIs/Bupropion? Many herbs can inhibit MAO to some degree and supplements like SAM-e affect neurotransmitters too.

I am mixing tramadol, idebenone, deprenyl, cordyceps, fish oil, coffee, nicotine, a host of adaptogens, and centrophenoxine right now with great results!!!

[spacey]

Is anybody here taking many supplements, herbs AND synthetic antidepressants like SSRIs/SNRIs/Bupropion? Many herbs can inhibit MAO to some degree and supplements like SAM-e affect neurotransmitters too.

I am mixing tramadol, idebenone, deprenyl, cordyceps, fish oil, coffee, nicotine, a host of adaptogens, and centrophenoxine right now with great results!!!

Lol I'd feel good flying high as a kite on tram aswell

[unbreakable]

Anyone who had a bad reaction to mixing SSRIs/SNRIs (tramadol is one too), Tricyclics or any Antidepressant in general with supplements/herbs? If yes, what did you take, which reaction occurred?

[luv2increase]

Anyone who had a bad reaction to mixing SSRIs/SNRIs (tramadol is one too), Tricyclics or any Antidepressant in general with supplements/herbs? If yes, what did you take, which reaction occurred?

I would say that it depends on the individual and what SSRI/SNRI that person is taking. Tramadol, as some of you may know, is a weakSNRI. So it will not have interactions with Deprenyl if deprenyl is not taken in high enough dosages to inhibit MAO-a (deals with serotonin). The main thing is to take it slow when combining these and do so at your own risk. Don't take 10 things with will affect a single neurotransmitter; that is just dumb. Like taking deprenyl in high enough dosages to inhibit MOA-b (dealing with deprenyl) would be not wise to take with amphetamines or a dopamine reuptake inhibitor such as ritalin or possibly even high dose l-phenylalanine/l-tyrosine.

One has to study the interactions of the supps to their prescription meds. One cannot basically take the contraindications listed for their medication as gospel. One really needs to do their own homework.


The point is to not take substances which increase a neurotransmitter in a way and another substance which increases that same neurotransmitter through a different mechanism concurrently; you may get away with lowered dosages of each but this is again at your own risk. You also have to watch out for substances which inhibit the enzymes used in the liver to break down that particular substance(s). This is just as dangerous as superfluous levels may ensue to cause great havoc; not safe.

Edited by luv2increase, 22 September 2008 - 04:46 PM.

[Bghead8che]

Is anybody here taking many supplements, herbs AND synthetic antidepressants like SSRIs/SNRIs/Bupropion? Many herbs can inhibit MAO to some degree and supplements like SAM-e affect neurotransmitters too.

I am mixing tramadol, idebenone, deprenyl, cordyceps, fish oil, coffee, nicotine, a host of adaptogens, and centrophenoxine right now with great results!!!

Lol I'd feel good flying high as a kite on tram aswell

No kidding. Tramadol can be very addictive and when I was taking it daily I was feeling great too! Just wait until you stop taking it.

[luv2increase]

No kidding. Tramadol can be very addictive and when I was taking it daily I was feeling great too! Just wait until you stop taking it.

I have, cold turkey too. The withdrawal is about 1/5 that of caffeine for me. I wouldn't be taking it but my back pain is just too much not to. I don't like the dopyness of narcotic pain medicines so I guess this will have to suffice.

[katzenjammer]

Does anyone know of celexa's effect on acetylcholine? I would like to take centrophenoxine (which does increase acetylcholine) and I'm not sure about combining them.

In general, I seem particularly sensitive to acetylcholine - even a little bit of ALCAR for example gets me so wired I can't sleep for days.

[luv2increase]

Does anyone know of celexa's effect on acetylcholine? I would like to take centrophenoxine (which does increase acetylcholine) and I'm not sure about combining them.

In general, I seem particularly sensitive to acetylcholine - even a little bit of ALCAR for example gets me so wired I can't sleep for days.

There is nothing in the literature about celexa and acetylcholine. I highly doubt celexa has anything to do with the neurotransmitter acetylcholine.


Why would you want to take centrophenoxine if you are sensitive to acetylcholine? ALCAR increases other neurotransmitters besides acetylcholine too.


edit: "can't sleep for days"??? Are you kidding me? You didn't take ALCAR. That is the most nonsense I've ever heard. I'm half tempted to discard your entire post as phony now.

Edited by luv2increase, 15 November 2008 - 09:30 PM.

[katzenjammer]

Does anyone know of celexa's effect on acetylcholine? I would like to take centrophenoxine (which does increase acetylcholine) and I'm not sure about combining them.

In general, I seem particularly sensitive to acetylcholine - even a little bit of ALCAR for example gets me so wired I can't sleep for days.

There is nothing in the literature about celexa and acetylcholine. I highly doubt celexa has anything to do with the neurotransmitter acetylcholine.

Thanks.

Why would you want to take centrophenoxine if you are sensitive to acetylcholine? ALCAR increases other neurotransmitters besides acetylcholine too.

I'm interested in the anti-aging benefits regarding lipofuscin.

edit: "can't sleep for days"??? Are you kidding me? You didn't take ALCAR. That is the most nonsense I've ever heard. I'm half tempted to discard your entire post as phony now.

I didn't mean literally - I meant that I get really wired and have trouble sleeping; and when I do sleep, it's of poor quality.

Edited by katzenjammer, 15 November 2008 - 09:45 PM.

[luv2increase]

Does anyone know of celexa's effect on acetylcholine? I would like to take centrophenoxine (which does increase acetylcholine) and I'm not sure about combining them.

In general, I seem particularly sensitive to acetylcholine - even a little bit of ALCAR for example gets me so wired I can't sleep for days.

There is nothing in the literature about celexa and acetylcholine. I highly doubt celexa has anything to do with the neurotransmitter acetylcholine.

Thanks.

Why would you want to take centrophenoxine if you are sensitive to acetylcholine? ALCAR increases other neurotransmitters besides acetylcholine too.

I'm interested in the anti-aging benefits regarding lipofuscin.

edit: "can't sleep for days"??? Are you kidding me? You didn't take ALCAR. That is the most nonsense I've ever heard. I'm half tempted to discard your entire post as phony now.

I didn't mean literally - I meant that I get really wired and have trouble sleeping; and when I do sleep, it's of poor quality.

On the bottle of the Unique Nutrition brand of Centrophenoxine, I believe it says that Centrophenoxine is a weak SNRI, yet I've yet to validate that claim, and I've looked everywhere on the Net to try and do so as well.

I'd say you'd be safe.

[Advanc3d]

i have taken 10mg Lexapro (SSRI) a day,

i also took SAM-E (400mg), 100mg 5-htp and a bunch of other things while on lexapro. no side effects were noted.