"Even if it has some (slight) benefit - wouldn't it be better to use that valuable 100 mg capsule space in OrthoCore for something else, like grape seed, green tea extract or resveratrol?"
Sure, but do you realize that some people might not be able to afford the multi if that happens? There's always things about a multi that could use improvement. In my opinion, AOR already did a good job at reinventing the multi.
To answer ur question. Making sure your inositol levels are not too low is a good thing, making it a priority is not worth it. I bet there's people who have used it in insanely high amounts with great results, you could therefore try it for yourself, and see if you notice anything. I for one don't.
You may need it depending on life style, diseases you have and drug intake.
Alcohol and coffee are inhibitors. If you are taking some types of antibiotics or sulfa drugs you may have low levels. If you have diabetes you probably have very low levels. So I guess an important part of the population could need it as a supplement.
Low levels are a contributing factor in abnormal platelet aggregation, alcoholism, heart disease, liver disease, memory loss, panic/anxiety attacks, and tardive dyskinesia. Additionally symptoms include eczema, hair loss, constipation, and abnormalities of the eyes and raised cholesterol.