In an interesting finding it seems that TERT, which controls telomerase is one of them.
Two lung cancer genes identified
Scientists find genetic variations that hike risk of the disease by 60 percent
http://www.msnbc.msn.com/id/27503938
The study published in the journal Nature Genetics included researchers from 18 countries who analyzed genetic mutations in more than 15,000 people -- 6,000 with lung cancer and 9,000 without the disease.
The researchers discovered a region on the fifth chromosome containing two genes — TERT and CRR9 — where they believe variations can boost the likelihood of lung cancer by as much as 60 percent.
"We are looking at versions of genes that everybody has," Brennan said in a telephone interview.
Not much is known about CRR9 but pinpointing the TERT gene is promising because it activates an enzyme called telomerase which is key to aging and cancer, Brennan said. (excerpt)
