2 replies to this topic

[OneScrewLoose]

I've read that deprenyl is an irreversible MAO inhibitor. Does that mean that if one were to stop taking it, they would not go back to the same state they started from?

[StrangeAeons]

irreversible refers to pharmacokinetics. There are competitive, noncompetitive, and irreversible medications when it comes to binding to a receptor. It just means that it cannot be displaced from the MAO molecule by another drug; but the drug will eventually release itself from MAO of its own accord.
Here's a little book on Google that might give you a slightly better explanation.

[Ben]

PKR is right. Eventually you will have functioning mao activity but you need to wait for the inhibition that deprenyl causes to wear off. I've heard that it can be up to a week. Consider that too when taking mulitple doses over a week the cumilative affect each dose is having on the others. There's more of this on the forum though. The search function works great.