Diabetes

That's so strange that no one has responded to this. Isn't diabetes what GSK is hoping to market their new res drug as a treatment for? Ok let's open it up a little does anyone know anyone else that has used res for diabetes and has seen some positive results? If so what?

Crep

Ok I'll comment. In my case there are a lot of wandering variables, and diabetes is difficult to pin down anyway. A LOT has changed in my life so I can't pin it all on the Resveratrol. During this time I also started on 30g daily Actos which, unfortunately could be having more effect than the Resveratrol. I also cut metformin from 2g daily to 1g, and glyburide from 20mg daily down to 10.

There are so many variables that I didn't want to comment without more certainty. However I found it astonishing that I could cut back the metformin and glyburide so significantly and still see a drop in fasting sugar and A1C. I don't think it's all due to the Actos.

But in the past year or so I have made some changes, including six months or so that I have been taking Resveratrol in an increasing laddering fashion. I have seen a lot of changes and some of those are consistent with other posters' experiences.

My body has carried progressively worse Type II for about five years. My body started out overweight, but on the right track, eating very well and running every day. However since being diagnosed, my blood pressure has increased to hypertension, hunger has never been sated, and exercise has been difficult at best. My body has consistently gained weight, about 15 pounds over time, and constantly feelt "out of gas". There have also been nightmares, insomnia, and a severe lack of mental clarity. It feels like being half asleep all the time, plus frequent needing to urinate, yet not being able to sleep well at night at all.

I have always attempted to exercise and my body has not made it past about five minutes of cardio before burning out. I have always attemted to eat healthfully, but my body constantly craved sugar. Stress has also been a huge factor, and a lot has changed in that direction too.

Since taking Resveratrol, Piracetam, alpha-lipoic acid and engaging mild intermittent exercise I have noted a lot of changes.

I began with 200 mg Res daily, scaled to 400 50%, scaled up to 99% 1G, and progressed to 3 to 4 grams a day. This was over the course of about two months, and I continued to use it at 3 to 4 grams daily for the next four months, which approximately comes up to today. (it mixes with wine, and peanut butter, and milk, but my best experience has been with whole yogurt, the stuff mixes thoroughly and doesn't settle out at all. I use Revgenetics, with thanks to Anthony for a great product. I also seem to get better personal results breaking the dosage into two even doses, morning and evening.)

First I have been sleeping better than I ever have. This I think is partly due to the Piracetam, which also granted tremendous clarity, understanding, retention and vivid dreams. That's a whole story in itself, but I would say to anyone on the fence, don't even hesitate, it's well worth it. It seems unusual that in my case it took 12 grams of Piracetam twice a day to get those results. I have scaled back a little. Funny, too, like someone else on erowid, I make more spelling typos when touch-typing. The fact that I recall that posting, which I saw only once several months ago, is also a sign of the better recall.

Second my fasting sugar has been declining in a stair-step fashion. It started between 200 and 230 on a regular basis with my A1C staying at 9.6 for a year. Since I took the Resveratrol, during a two month period with little exercise, my A1C went down to 9.3 . I'm no doctor but it seems to me any A1C drop in just two months is significant and probably unusual.

My daily sugar started having "reverse spikes" where one day it would be 167, the next back up to 200, same for a day or two, and back down to 167. After some weeks of this, 160 - 170 became the norm, and my glucose would drop into the 140 range in the same fashion. I had intermittent, rare days in the 120s and lower. That has not happened in years, in fact I don't recall my sugar ever being steady anywhere close to normal levels. The best consistent results I ever got was in the 140s, years ago.

The decrease has slowed down, and my sugar is generally in the 120 to 150 range now. However there are days when I've eaten a lot and found my sugar normal, or almost normal, the next day, which is astonishing. That has never happened.

During this time too, hunger is not what it used to be. The only way to describe this is: there is a difference between having an appetite, and actually feeling real hunger. Since the diabetes diagnosis, my hunger has never really gone down. The only time it has been sated, I have discovered my fasting sugar at 300 + . I have not had an appetite, ever, so much as actually felt as if my body was starving. Now, I have had times when there's food around, and there are no cravings. It's uncanny, it is the strangest feeling. I can actually tell the difference between feelings like starvation vs. feelings of just appetite. I no longer constantly crave food. There are actually times when I can take it or leave it, which has not happened since the initial diagnosis.

Other signs and symptoms have changed. I no longer need to urinate frequently, nor feel very thirsty. I used to go through the night sweating through my high glucose, it became a regular occurrence. This never happened before the diabetes, and seems to have gone away now.

Another thing another poster mentioned - exercise. There are times now when I can take up a regular physical activity and not be nearly as worn out. I still feel pretty out of shape, huffing and puffing, but - here's the difference - I can actually keep going. I went snorkeling recently for about six hours. That's a lot of activity for an obese diabetic with hypertension who hasn't exercised much in years. But I never really wore out, just slowed down from time to time, and although there were sore muscles, they were never as bad as the old days pumping iron back in the gym.

Oh and one more thing - up until this year, my body was almost constantly sick. Now, I've gone through a cold and barely noticed - a cold that kept some of my co-workers out of work. Seems like my immune system is doing better.

I've also sustained a few injuries and seem to be healing at a normal or faster than normal rate. It's hard to explain but I've sustained a couple of burns that I am pretty sure should have blistered, but have not, and healed faster than I think they should have. This is really hard to validate but my instincts tell me my healing is affected.

In sum my body seems to have undergone a sea change in a relatively short period of time. I really need to see a doctor in the Phoenix area that knows more about Resveratrol and more cutting-edge treatments. I'll continue with the diet and exercise and hope to cut the medication entirely over time. Like I said there are a lot of variables so I can't put it all to the Res and didn't want to speak too soon. But you asked and that is my experience so far, hope it helps and good luck.

~ neuromancer

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#1 Crepulance

#2 Crepulance

#3 neuromancer

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