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Eggs, Choline, and Epigenetic Cancer Protection


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#1 Mind

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Posted 02 December 2008 - 06:24 PM


Eating eggs when pregnant affects breast cancer progression in offspring

The only recent negative comment I heard about eggs was at Terry Grossman's Convergence Presentation. He said you should only have 1 or 2 egg yolks per week to avoid some sort of acid (begins with an "A", never heard of it before, can't remember the name...).

The researchers made the discovery in rats by studying females whose mothers were fed varying amounts of choline during pregnancy. Different groups of pregnant rats received diets containing standard amounts of choline, no choline at all, or extra choline. Then the researchers treated the female offspring with a chemical that causes cancer of the mammary gland (breast cancer). Although animals in all groups developed mammary cancer, the daughters of mothers that had received extra choline during pregnancy had slow growing tumors while daughters of mothers that had no choline during pregnancy had fast growing tumors.

"Our study provides additional support for the notion that choline is an important nutrient that has to be considered when dietary guidelines are developed," said Krzysztof Blusztajn, Ph.D., Professor of Pathology at Boston University and the study's senior researcher. "We hope it will be possible to develop nutritional guidelines for pregnant women that ensure the good health of their offspring well into old age."



#2 kismet

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Posted 02 December 2008 - 06:32 PM

Michael recently voiced his concern/negativity towards eggs and promised to deliver... studies ... I guess? Most often his opinion is well researched so I'm looking forward to hearing more about the issue.
"...whole eggs (as vs eggwhites) should be avoided because of the saturated fat and cholesterol (yes, the latter actually is bad for you ... more on this later); and even eggwhites are extremely high in methionine, so you'll not want to rely on them much."

Personally I don't have much to add, I'm way too biased, I love eggs!

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#3 Shepard

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Posted 02 December 2008 - 06:34 PM

The only recent negative comment I heard about eggs was at Terry Grossman's Convergence Presentation. He said you should only have 1 or 2 egg yolks per week to avoid some sort of acid (begins with an "A", never heard of it before, can't remember the name...).


He was talking about arachidonic acid. They harp on it in Fantastic Voyage. This is another one of those fats that has been given a generalized bad name.

#4 edDe

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Posted 02 December 2008 - 07:03 PM

The only recent negative comment I heard about eggs was at Terry Grossman's Convergence Presentation. He said you should only have 1 or 2 egg yolks per week to avoid some sort of acid (begins with an "A", never heard of it before, can't remember the name...).


He was talking about arachidonic acid. They harp on it in Fantastic Voyage. This is another one of those fats that has been given a generalized bad name.


Here is a "fluff" article by Barry Sears which talks about the evils of arachidonic acid :

http://www.cbn.com/h...idonicacid.aspx

I've never given it much though myself either. I don't eat much red meat. But I have
eggs about twice a week. In fact, I having them tonight.

#5 kismet

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Posted 03 December 2008 - 12:22 AM

Not news per se, but I'd like to add it nonetheless.

“It is notable that eggs are one of the richest sources of biotin, riboflavin and pantothenic acid (33) and that epidemiological studies conducted in the same city where the cohort of our study resided (Adelaide, South Australia), using a similar dietary questionnaire, have shown an increased risk for colon and pancreatic cancer with increased egg intake” [1]
All those 3 vitamins are associated with reduced genome stability as assesed by the micronucleus test.

[1]
http://www.imminst.o...mp;#entry253086
http://carcin.oxford...t/full/26/5/991

Edited by kismet, 03 December 2008 - 12:23 AM.





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