2 replies to this topic

[argon]

A year ago, while doing push-ups, I injured cartilage at the costochondral junction (where the ribs meet the sternum). A physiotherapist indicated the injury was likely due to having exceptional flexibility (thus, "stretchy" connective tissue) and over-extending during exercise; and that the injury would likely take months to heal. A year later, the injury persists.

For the last 18 months, I've taken 1500mg resveratrol daily. I'm wondering, is there any evidence that resveratrol might actually be slowing the healing process? Researchers at Ohio State University found that resveratrol prevented excess growth of collagen (fibrosis) in heart tissue in hypertension and heart failure:
http://www.lef.org/n.../2004_12_09.htm
I'm wondering if this tendancy to reduce collagen growth might go beyond heart tissue and affect recovery from an injury to connective tissue in other parts of the body.

As background, I'm a 30yrs male otherwise in good health.

Thanks for any input you can provide.

[rwac]

Here's a whole thread dedicated to Resveratrol causing joint problems

Resveratrol-Joint Pain, Developed joint pain after a few months on Resv

[maxwatt]

A year ago, while doing push-ups, I injured cartilage at the costochondral junction (where the ribs meet the sternum). A physiotherapist indicated the injury was likely due to having exceptional flexibility (thus, "stretchy" connective tissue) and over-extending during exercise; and that the injury would likely take months to heal. A year later, the injury persists.

For the last 18 months, I've taken 1500mg resveratrol daily. I'm wondering, is there any evidence that resveratrol might actually be slowing the healing process? Researchers at Ohio State University found that resveratrol prevented excess growth of collagen (fibrosis) in heart tissue in hypertension and heart failure:
http://www.lef.org/n.../2004_12_09.htm
I'm wondering if this tendancy to reduce collagen growth might go beyond heart tissue and affect recovery from an injury to connective tissue in other parts of the body.

As background, I'm a 30yrs male otherwise in good health.

Thanks for any input you can provide.

This is a good question. There have been several studies showing resveratrol may prevent heart disease by preventing fibrosis, thought the mechanism may not involve extra-cellular collagen, or may involve inhibition of angiogenesis. The same mechanisms could possibly prevent or slow healing of tendons. Not enough is known yet, there have not been sufficient studies. In the meantime, you could try taking a vacation from resveratrol and see if healing proceeds. Tendon and connective tissue are very slow to heal in any case, having very poor blood supply, so resveratrol may not be the culprit. Ont he other hand, if it does inhibit angiogenesis even slightly, it could inhibit such healing. Let us know what happens.