7 replies to this topic

[tlm884]

I was just curious as to why there is such talk about pot usage on this forum? I thought this forum was aimed at lenghthing your life?

[Shannon Vyff]

Most likely because people like its effects, they'd like that there be benefits.

[luv2increase]

Most likely because people like its effects, they'd like that there be benefits.

lol.. That just isn't the case though.


If you smoke weed, you are shortening your lifespan.

On the other hand, if you "eat" weed it isn't as bad. It just will make you an unproductive loser 99.99% of the time.

[Shannon Vyff]

I considered saying that you can eat it, but that can be dangerous too depending on your genes (this is not to mention the problems with addiction in how THC regulates your mood)--but here, THC can be very detrimental for some people, here is one point: http://www.cannabis-...n_2008_04_1.pdf and http://www.bmj.com/c...l/325/7374/1212

You can shorten your lifespan by eating it as well. But hey, some people have genes than enable them to live to 120 smoking--its all averages though for those that try to choose the healthiest ways of living based on what data we have.

[RunterBeaker]

In my experience, marijuana was a tool for self understanding and self awareness... initially. Then I used it to escape reality, I just kept getting stoned, I thought I was learning from it but the benefits had passed a long time ago. All it was doing was keeping me down, holding me back from moving on in life, not to mention impairing my short and long term memory as well as my ability to learn.

[acen]

Stop listening to the propaganda. That crap about cannabis causing schizophrenia has been debunked. It can only trigger it in people that are already schizophrenic, which should be obvious since cannabis is a psychedelic. I thought this forum was supposed to be for scientific discussion.


Endocannabinoids in the retina: from marijuana to neuroprotection.

There is great interest in endocannabinoids for their role in neuroplasticity as well as for therapeutic use in numerous conditions, including pain, stroke, cancer, obesity, osteoporosis, fertility, neurodegenerative diseases, multiple sclerosis, glaucoma and inflammatory diseases, among others. However, there has been relatively far less research on this topic in the eye and retina compared with the brain and other organ systems.

US Patent 6630507: Cannabinoids as antioxidants and neuroprotectants

Cannabinoids have been found to have antioxidant properties, unrelated to NMDA receptor antagonism. This new found property makes cannabinoids useful in the treatment and prophylaxis of wide variety of oxidation associated diseases, such as ischemic, age-related, inflammatory and autoimmune diseases.
Assignee: The United States of America as represented by the Department of Health and Human Services

9-Tetrahydrocannabinol Inhibits Cell Cycle Progression in Human Breast Cancer Cells through Cdc2 Regulation

It has been proposed that cannabinoids are involved in the control of cell fate. Thus, these compounds can modulate proliferation, differentiation, and survival in different manners depending on the cell type and its physiopathologic context. However, little is known about the effect of cannabinoids on the cell cycle, the main process controlling cell fate. Here, we show that {Delta}9-tetrahydrocannabinol (THC), through activation of CB2 cannabinoid receptors, reduces human breast cancer cell proliferation by blocking the progression of the cell cycle and by inducing apoptosis.

Cannabinoid receptor-independent cytotoxic effects of cannabinoids in human colorectal carcinoma cells: synergism with 5-fluorouracil.

Cannabinoids (CBs) have been found to exert antiproliferative effects upon a variety of cancer cells, including colorectal carcinoma cells. However, little is known about the signalling mechanisms behind the antitumoural effect in these cells, whether the effects are shared by endogenous lipids related to endocannabinoids, or whether such effects are synergistic with treatment paradigms currently used in the clinic.

Nontoxic Dose of Δ9-THC Kills Human Brain Tumor Cells

After 20 hours of treatment, Δ9-THC kills all cancer cells but leaves normal brain cells alive. Cell death is evidenced by cells shrinking to inanimate white spheres.

JunD is involved in the antiproliferative effect of Delta9-tetrahydrocannabinol on human breast cancer cells.

It has been recently shown that cannabinoids, the active components of marijuana and their derivatives, inhibit cell cycle progression of human breast cancer cells. Here we studied the mechanism of Delta(9)-tetrahydrocannabinol (THC) antiproliferative action in these cells, and show that it involves the modulation of JunD, a member of the AP-1 transcription factor family. THC activates JunD both by upregulating gene expression and by translocating the protein to the nuclear compartment, and these events are accompanied by a decrease in cell proliferation.

Suppression of Nerve Growth Factor Trk Receptors and Prolactin Receptors by Endocannabinoids Leads to Inhibition of Human Breast and Prostate Cancer Cell Proliferation

Antitumor Activity of Plant Cannabinoids with Emphasis on the Effect of Cannabidiol on Human Breast Carcinoma

Cannabidiol-Induced Apoptosis in Human Leukemia Cells: A Novel Role of Cannabidiol in the Regulation of p22phox and Nox4 Expression

Cannabinoids Inhibit the Vascular Endothelial Growth Factor Pathway in Gliomas

Inhibition of Glioma Growth in Vivo

Cannabinoids Induce Apoptosis of Pancreatic Tumor Cells via Endoplasmic Reticulum Stress–Related Genes

Cannabidiol lowers incidence of diabetes in non-obese diabetic mice.

Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors

Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis

Antibacterial Cannabinoids from Cannabis sativa: A Structure−Activity Study

Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug

The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis

Cannabinoids inhibit neurodegeneration in models of multiple sclerosis

Cannabinoids in bipolar affective disorder: a review and discussion of their therapeutic potential.

Delta-9 tetrahydrocannabinol (THC) inhibits lytic replication of gamma oncogenic herpesviruses in vitro

Cannabinoid activation of PPARalpha; a novel neuroprotective mechanism

Cannabinoids and Neuroprotection in Global and Focal Cerebral Ischemia and in Neuronal Cultures

Neuroprotection by Delta 9-Tetrahydrocannabinol, the Main Active Compound in Marijuana, against Ouabain-Induced In Vivo Excitotoxicity

Comparison of Cannabidiol, Antioxidants, and Diuretics in Reversing Binge Ethanol-Induced Neurotoxicity

Cannabinol delays symptom onset in SOD1 (G93A) transgenic mice without affecting survival.

Neuroprotective and Blood-Retinal Barrier-Preserving Effects of Cannabidiol in Experimental Diabetes

Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects

Prevention of Alzheimer's Disease Pathology by Cannabinoids: Neuroprotection Mediated by Blockade of Microglial Activation

Nonpsychoactive Cannabidiol Prevents Prion Accumulation and Protects Neurons against Prion Toxicity

+ much much more

Please stop perpetuating ignorance.

Edited by acen, 19 February 2009 - 07:12 PM.

[RunterBeaker]

I have no idea how that got posted so many times.


Relaying personal experience is NOT perpetuating igorance. And you did not show the video of neuroligist examining the brain of someone who smoked habitually for many years. Key areas of the brain were not as active as non smokers.

Edited by RunterBeaker, 19 February 2009 - 09:31 PM.

[acen]

I would never suggest smoking anything