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Melanotan2?


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#1 Barksdale

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Posted 24 March 2009 - 07:19 PM


I'm going to use Melanotan2 for tanning now. Is it going to affect my aging?

Thanks..

#2 renwosing

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Posted 25 March 2009 - 12:43 AM

Your moles on your body will turn darker, and some enlarged.

Renwosing

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#3 renwosing

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Posted 25 March 2009 - 08:16 AM

Another thing, your nipples will be darkened too:P

Dunno if the pigmentation is reversible after you stop using it.

Renwosing

#4 tunt01

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Posted 25 March 2009 - 10:16 AM

i looked at it pretty closely. i think it's probably a pro-aging drug.

pigmentation will reverse after you stop using it for an extended period of time. it functions just like a tan, only it is hormonally induced.

it is a peptide hormone... most hormones are pro aging.

Edited by prophets, 25 March 2009 - 10:46 AM.


#5 Barksdale

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Posted 26 March 2009 - 09:35 AM

i looked at it pretty closely. i think it's probably a pro-aging drug.

pigmentation will reverse after you stop using it for an extended period of time. it functions just like a tan, only it is hormonally induced.

it is a peptide hormone... most hormones are pro aging.


U shure it's a pro-aging drug? I so want a tan though, but my biggest concern right now is that my dad almost got mole cancer. And several people in his family has had cancer and his aunt died from it. I think the best way is to be really careful and check the new moles often. Because the way I see it tanning saloon are more bad than MT2. If I had a darker skin (e.g type 3) I would go for tanning saloon + betacaroten etc, but since my skin is pretty fair, I think MT2 is the best.

#6 tunt01

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Posted 26 March 2009 - 12:08 PM

U shure it's a pro-aging drug? I so want a tan though, but my biggest concern right now is that my dad almost got mole cancer. And several people in his family has had cancer and his aunt died from it. I think the best way is to be really careful and check the new moles often. Because the way I see it tanning saloon are more bad than MT2. If I had a darker skin (e.g type 3) I would go for tanning saloon + betacaroten etc, but since my skin is pretty fair, I think MT2 is the best.



i can only be truly sure the sun will rise in the east, set in the west, and that i have to pay taxes every year.

i have spent a ton of time on the melanotan.org forums, i have gone through all of the clinuvel presentations, and spent a lot of time looking at the drug and a few of the studies. i have spoken to one person who was in a clinical trial who had glowing reviews of it and intends to use it when it becomes available.

1. i personally have a strong view that inserting hormones into your body is a bad idea.
2. i think stimulating your own personal immunity over time to the sun is healthier and more natural. if i could, i would try to get 15-30 mins of sun every day.
3. M1 is a total piece of junk and cross the blood brain barrier. M2 is the only viable peptide hormone. i can't believe anyone would take M1, which had its drug development stopped for obvious risk reasons.
4. i have very pale skin (english blood), work in an office all day, and M2 is of real interest to me. but im not willing to sacrifice any personal health for this stuff. let 5,000-10,000 other people use this stuff for an extended period of time (years) before i will touch it. i'm not ready to risk skin cancer by bombarding my melanocytes excessively with a hormone. i personally like precursors to hormones (amino acids, etc.) where the body does it's own endogenous work, rather than ingesting the hormone directly.
5. i work in an office all day, have zero exposure to the sun, take vitamin D. if i was planning a trip on a safari to africa where i would be exposed to the blazing sun for 2 weeks straight w/ my existing pale skin, then i would probably do 1 cycle of the stuff to build up an immunity. the trade-off would make sense.
6. i would never use a tanning salon. it's moronic, imo.

im not a scientist. i am a researcher for an investment fund and i took a hard look at cilnuvel for a potential investment. i was initially very positive on them, but they have a risky patent position and i stopped working on it. it's probably going to get a ton of off label use like HGH does, but that drug is clearly pro-aging and doesn't make it right.


i dont like to take risks. it's just how i see things. that's my view... you will have to come to your own.'

Edited by prophets, 26 March 2009 - 12:19 PM.


#7 renwosing

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Posted 26 March 2009 - 12:54 PM

prophets,

so you saying all petide hormones r pro-aging?

does that include rHGH too?

Renwosing

#8 tunt01

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Posted 26 March 2009 - 01:04 PM

prophets,

so you saying all petide hormones r pro-aging?

does that include rHGH too?

Renwosing


i'm generalizing. generally increasing your hormone output tends to be risky. obviously if a person is GH deficient, then HGH or rHGH might make sense. if you are 15 yrs old, and short stature / underdeveloped then GH probably makes sense. if a person has a real genetic disorder like EPP where the sun can literally kill them, then M2 is a godsend. it all depends.

i believe strongly in figuring out your own health risks/needs and what you should put into your body. i have my own personal files and copies of every medical test/annual physical i have done sitting in my office, not just my doc's. i view doctors as trained consultants and experts, but not necessarily the people who know exactly what is right for me. i certainly don't expect a drug company to know what is best for me. im sure any drug company would like to slap a label on every vial that goes out the door saying what they make is safe and for use by every person in the world.

if you are generally a healthy person, then going to the gym and working out is probably the safest way to increase your own GH levels. other than that, i can't say on rHGH vs. HGH vs. IGF-1 etc. talk to an endocrinologist and get their expert/consultants viewpoint.

#9 Barksdale

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Posted 26 March 2009 - 01:15 PM

So what about all the people that uses HGH?

http://www.side2.no/...icle2476562.ece

#10 tunt01

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Posted 26 March 2009 - 01:23 PM

http://lmgtfy.com/?q... +"cancer risk"

#11 VespeneGas

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Posted 26 March 2009 - 05:41 PM

http://lmgtfy.com/?q... +"cancer risk"


I rofl'ed

But more seriously, we don't yet know what effect Melanotan ii has on aging, if any. Use at your own peril!!!!!

...but more seriously still, I'm considering trying it :|?

#12 Guacamolium

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Posted 27 March 2009 - 01:57 AM

I tried it last year, and the absolute worst regret I have from trying it is that it created new freckles - semi large ones - all around my body, particularly my face. Now I have three freckles on the right side of my face that stayed after the sun tan went away. Definitely go light on the dosages - as I did, but get sun exposure if you dose or else the melanogenesis will manifest as freckles, if you're anything like me.

#13 tunt01

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Posted 27 March 2009 - 02:18 AM

lot of people said they had a had a pretty big pick up in freckles.

it just strikes me as very early to be playing w/ this kind of hormone. i'd rather not be a pioneer of this kind of thing. i dont need the melanoma risk.

#14 Barksdale

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Posted 27 March 2009 - 08:05 AM

I tried it last year, and the absolute worst regret I have from trying it is that it created new freckles - semi large ones - all around my body, particularly my face. Now I have three freckles on the right side of my face that stayed after the sun tan went away. Definitely go light on the dosages - as I did, but get sun exposure if you dose or else the melanogenesis will manifest as freckles, if you're anything like me.


I'm sorry to hear about the freckles man, but can't you remove them someway? I think it depends on what skin type you are too, I'm a 2, what are you?=P I think one should get sun exposure after about 20mg, however, I'm not quite sure. I need to research this some more.

#15 tunt01

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Posted 27 March 2009 - 09:25 AM

you can get the freckles laser'd off.

there are a couple examples of people who took melanotan, then blew up in freckles, had them lasered off, and subsequently look very good.

#16 Barksdale

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Posted 27 March 2009 - 10:19 AM

Are there some other sites with great information about melanotan? I know about the forum, but I'm looking for some more too:)

#17 tunt01

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Posted 27 March 2009 - 12:57 PM

i think that melanotan.org forum is the best site. even the research reports that i've read from ABN AMRO and other investment banks are pretty meager in their analysis of the risks/value of the molecule.

i think you would really have to do a lot of your own homework outside of just casually reading the forum or clinuvel's website (www.clinuvel.com). you would have to try to track down scientists at university of arizona (where the molecule was invented) or call up Palatin (sp?) Technologies, the guys who owned the patent rights to M1.

youtube has a few clips on M2, but not much more information is provided other than what you've probably already read in the online newspaper articles.

dunno, i think it's probably more cut and dry, than you or I might think. the molecule is pretty specific, targets the melanocytes, it does not cross the blood brain barrier, has been tested in hundreds of people, and clearly works.

i guess for me what it comes down to is: Do I really need this? Do I really need to put this thing in my body? The answer for me is clearly no.

#18 Mixter

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Posted 27 March 2009 - 01:14 PM

If you really must tan, use a topic cAMP inducer like forskolin instead, and tan in the sun with a mild sun blocker.
http://www.wired.com...s/2006/10/71879

Also, take fern (Polypodium l.) extract to guard against harmful effects of sun tanning:
http://www.cpnhelp.org/node/4709

#19 Barksdale

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Posted 01 April 2009 - 07:31 PM

Did my first injection today. I got really red so I guess I took too much. Out of a 10mg MT2 + 2ml sterile water I took a 0.8ml injection, perhaps that was too much?

Anyway, it's recommended to get as little as possible sun exponation until you have reached 30mg. Should I wear a faceblock then?

#20 VespeneGas

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Posted 01 April 2009 - 07:38 PM

Did my first injection today. I got really red so I guess I took too much. Out of a 10mg MT2 + 2ml sterile water I took a 0.8ml injection, perhaps that was too much?

Anyway, it's recommended to get as little as possible sun exponation until you have reached 30mg. Should I wear a faceblock then?


You injected 2.5 mg of MT2. People on the melanotan forums recommend 0.5 mg per day, so you've quintupled the recommended dose. Don't do that.

#21 Barksdale

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Posted 01 April 2009 - 07:55 PM

Did my first injection today. I got really red so I guess I took too much. Out of a 10mg MT2 + 2ml sterile water I took a 0.8ml injection, perhaps that was too much?

Anyway, it's recommended to get as little as possible sun exponation until you have reached 30mg. Should I wear a faceblock then?


You injected 2.5 mg of MT2. People on the melanotan forums recommend 0.5 mg per day, so you've quintupled the recommended dose. Don't do that.


Wtf, are you serious? My plan was to take 0.25mg..Will I get a lot of moles from this one mistake even if I'll do 0.25-0.50mg the other days?


edit: WAIT!, I mean I took 0.08ml not 0.8ml..

Edited by Barksdale, 01 April 2009 - 07:57 PM.


#22 tunt01

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Posted 01 April 2009 - 08:04 PM

this isn't the place to be asking for dosage levels of MT2. I would suggest you go to the melanotan.org forums and discuss it with them.

if you want good information, go to the most experienced source.
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#23 Gerald W. Gaston

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Posted 01 April 2009 - 09:38 PM

We discussed MII here a few years ago. See this thread:

REAL sunless tanner -- Forskolii in "Nature" mag


I briefly mentioned my experience with it on the 3rd page of that.

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#24 Raptor87

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Posted 07 August 2011 - 04:44 AM

Would be an awesome way to get a tan if its not dangerous...

What´s the latest news on melanotan2?

Is it dangerous?




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