132 replies to this topic

[Fred_CALICO]

「饮食如诗，简而不凡」



Warren Buffett adopts a notoriously singular diet, marked by a daily consumption of around five cans of Coca-Cola and regular breakfasts at McDonald's - a routine he adjusts according to stock market fluctuations (for example, choosing between a $2.95 or $3.17 menu depending on the mood of the markets). This diet, rich in sugars and calories, contrasts sharply with conventional nutritional advice. Nevertheless, Buffett attributes his longevity (at 94) mainly to regular sleep (around eight hours a night) and effective stress management, rather than to a balanced diet or systematic intake of dietary supplements.



Indeed, there is no evidence to suggest that he consumes dietary supplements on a regular basis. His lifestyle thus illustrates an approach to life based on extreme simplicity and a focus on intellectual activities - such as intensive reading (500 pages a day) - and work, rather than on constant efforts to optimize his nutritional intake through supplements.

« 精微难略，简概失真 »

https://www.guoxueda...yanbian/1244qr/

[alphachn]

「饮食如诗，简而不凡」



Warren Buffett adopts a notoriously singular diet, marked by a daily consumption of around five cans of Coca-Cola and regular breakfasts at McDonald's - a routine he adjusts according to stock market fluctuations (for example, choosing between a $2.95 or $3.17 menu depending on the mood of the markets). This diet, rich in sugars and calories, contrasts sharply with conventional nutritional advice. Nevertheless, Buffett attributes his longevity (at 94) mainly to regular sleep (around eight hours a night) and effective stress management, rather than to a balanced diet or systematic intake of dietary supplements.



Indeed, there is no evidence to suggest that he consumes dietary supplements on a regular basis. His lifestyle thus illustrates an approach to life based on extreme simplicity and a focus on intellectual activities - such as intensive reading (500 pages a day) - and work, rather than on constant efforts to optimize his nutritional intake through supplements.

« 精微难略，简概失真 »

https://www.guoxueda...yanbian/1244qr/

As we have discussed, aging begins with the education of infants to learn survival mechanisms. Compulsory behaviors tend to accelerate aging. Buffett is a wealthy man who lives a stress-free life, doing what he pleases. This is a form of longevity behavior. Trump is another example; he loves Coca-Cola, which is considered a behavior leading to aging in scientific papers, yet it presents a contradictory phenomenon in real human life. Many research papers on whale longevity suggest that a low metabolic rate or a low rate of epigenetic changes contribute to their longevity. In fact, the upstream reason is that whales do not need to learn or develop skills; they simply open their mouths and have food.

Edited by alphachn, 21 March 2025 - 12:57 PM.

[alphachn]

As we have discussed, aging begins with the education of infants to learn survival mechanisms. Compulsory behaviors tend to accelerate aging. Buffett is a wealthy man who lives a stress-free life, doing what he pleases. This is a form of longevity behavior. Trump is another example; he loves Coca-Cola, which is considered a behavior leading to aging in scientific papers, yet it presents a contradictory phenomenon in real human life. Many research papers on whale longevity suggest that a low metabolic rate or a low rate of epigenetic changes contribute to their longevity. In fact, the upstream reason is that whales do not need to learn or develop skills; they simply open their mouths and have food.

Organisms without nerves have a long survival time, such as trees, bacteria, viruses, etc. Our replenishment plan is to minimize the harmful substances produced by these survival skills.

Edited by alphachn, 21 March 2025 - 01:31 PM.

[Fred_CALICO]

https://chatgpt.com/...64-91ce412ef4cf

I've been researching an AI on stress management with essential oils (my favorite area of knowledge) and plants.

From my bookish AND practitioner knowledge, I can say that (concerning Essential Oils) the AI results are quite good. Keep a critical eye and check, of course, but that's what you have to do anyway, whatever the circumstances.

It's a new tool for unburdening the memory, and thus freeing up mental space to go from rambling to daydreaming. 2025: Make way for serendipity!

For personal, scientific and product availability reasons:

HE : Encens (Boswellia spp.) + Jatamansi (Nardostachys jatamansi)
Plants : Ashwagandha (Withania somnifera) + Brahmi (Bacopa monnieri) + Gotu Kola (Centella asiatica)

[longevitydiary]

https://chatgpt.com/...64-91ce412ef4cf

I've been researching an AI on stress management with essential oils (my favorite area of knowledge) and plants.

From my bookish AND practitioner knowledge, I can say that (concerning Essential Oils) the AI results are quite good. Keep a critical eye and check, of course, but that's what you have to do anyway, whatever the circumstances.

It's a new tool for unburdening the memory, and thus freeing up mental space to go from rambling to daydreaming. 2025: Make way for serendipity!

For personal, scientific and product availability reasons:

HE : Encens (Boswellia spp.) + Jatamansi (Nardostachys jatamansi)
Plants : Ashwagandha (Withania somnifera) + Brahmi (Bacopa monnieri) + Gotu Kola (Centella asiatica)

Yes, many medicines in this field, such as CBD and various antidepressants, have life-extending effects. However, although these can be somewhat effective, they mainly serve a preventive role. Our company is more focused on treatment methods after issues arise, which involves eliminating harmful substances and maintaining internal balance. We believe this is crucial because, as intelligent beings, humans are inevitably prone to imbalance. The rate of this imbalance is the speed at which we age.

 

Take Presidents Trump and Biden as an example; they are only three years apart in age, yet their states are completely different. President Trump can make decisions without much thought. For instance, he announced additional tariffs on small packages from China on February 1st, but upon realizing that it caused chaos, he signed an executive order on February 8th to retain the tariff exemption for packages under $800 (a decision made after simple consideration). In contrast, President Biden would likely consult with China or carefully study the potential impact before making such a decision (a decision made after complex consideration).

 

Another example is Presidents George W. Bush and Bill Clinton. After being hit by a shoe, Bush could still make a joke about it. Clinton, on the other hand, remains very active in politics even after retirement. Their states are entirely different. There's an old Chinese saying that foolish people live longer. In modern times, there's a phenomenon where bad people (those who act freely without moral constraints) tend to live longer. Movies often promote love, but love can also mean attachment, and attachment can accelerate aging.

[alphachn]

It is obvious that Trump and Bush did not exercise and exercise regularly. They have golf that is at least playful in nature. And the results of mouse CR and exercise prolonging lifespan are different in different laboratory research papers? We believe it is because the experimental environment provided to the mice in the experiment was different and did not take into account the factor of consciousness response.

Edited by alphachn, 21 March 2025 - 04:20 PM.

[Fred_CALICO]

"He who sows knowledge reaps wisdom." 业 return |--> 業

Elon Musk’s dietary approach is as unconventional as his business ventures. He’s famously mentioned that he eats a donut every morning—a quip that underlines his preference for convenience and taste over rigid health rules. In interviews and social media posts, he’s admitted that he’d rather enjoy “tasty food” even if it might shorten his lifespan, emphasizing that eating is more about sustaining energy during his hectic workdays than about strict nutrition.

When it comes to managing his weight, Musk has incorporated intermittent fasting into his routine. More recently, he’s turned to weight‐loss medications—specifically GLP-1 receptor agonists like Ozempic, Wegovy, and now Mounjaro—to help curb his appetite and trim down. Although these drugs are prescription medications rather than traditional over-the-counter dietary supplements, they play a key role in his strategy to achieve a “fit, ripped” look while keeping meal times minimal.

Beyond these measures, Musk hasn’t publicly detailed a regimented use of vitamins or other supplements. Instead, his overall “diet” seems driven by practicality, favoring quick, energy-sustaining choices over elaborate, health-focused meal plans.

[longevitydiary]

1. Atherosclerosis is the primary culprit behind severe cardiovascular events such as myocardial infarction and stroke. For a long time, cholesterol has been widely considered the main inducer of atherosclerosis. Current drug treatment strategies mainly focus on lowering low-density lipoprotein cholesterol (LDL-C). Although statins and other lipid-lowering drugs have reduced the risk of adverse cardiovascular events by about one-third, a significant number of patients still face "residual risk" and experience adverse cardiovascular events even when their blood lipid levels have been reduced to target levels. Especially in patients with chronic kidney disease (CKD), as renal function gradually declines, the efficacy of preventing cardiovascular diseases by lowering cholesterol diminishes, almost disappearing in end-stage renal disease patients. Therefore, finding new anti-atherosclerotic strategies beyond lowering cholesterol is currently a focal point of international concern. Professor Kong Wei's team, while analyzing blood samples from 4,236 coronary heart disease patients, discovered a startling fact: for every 1 μmol/L increase in ceramide concentration per microliter of blood, the volume of coronary artery plaque would expand by 3.7%. When the test value reaches the warning threshold, the volume of plaques within the patient's vessels may double within five years. This lipid metabolite also activates the "self-destruction program" of macrophages, prompting them to engulf oxidized low-density lipoprotein, ultimately forming lethal foam cells. It is evident that ceramide is the core driving force behind plaque growth.
2. This study shows that although higher levels of physical activity seem to lower the risk of death in the short term, in the long run, extreme activity does not show a lower mortality rate compared to complete sedentary behavior. https://www.jyu.fi/e...rs-new-insights
3. Many studies have shown that lifespan is inversely proportional to heart rate, with a lower heart rate associated with a longer life. As a result, many people engage in exercise to lower their heart rate, which implies that exercise can extend life. We believe that heart rate may also represent a person's lower neural processing rate, and it might not be due to the exercise itself.

Attached Files

•  w700d1q75cms.jpg   17.4KB   0 downloads

Edited by longevitydiary, 24 March 2025 - 09:12 AM.

[longevitydiary]

 Retraction of 2012 paper on Parkinson's fromJohns Hopkins University. Cited 67 times.

 

Curcumin is extremely popular in the world and has almost become a "star ingredient" in the health supplement industry, particularly highly regarded in the fields of natural anti-inflammatory, antioxidant, and functional health. 

Actually Curcumin is a PAINS（pan-assay interference compounds） and it yields several false positives, the same is true for catechol compounds.

Attached Files

•  微信图片_20250509160122.jpg   153.87KB   0 downloads

Edited by longevitydiary, 09 May 2025 - 08:10 AM.

[longevitydiary]

A geomagnetic storm occur in the past three days. There is a  visible auroras in the northern part of china, with some areas even experiencing red-green composite auroras.BTW, bio-geeks are really into magnetic storms device.  

 

Attached Files

•  微信图片_20250603163906.jpg   241.65KB   0 downloads

[longevitydiary]

When oxygen is low, such as heart attacks and strokes causes tissue and organ damage. The study suggests that bursting red blood cells, not blood clots, are the culprits.

https://www.nature.c...586-025-09076-x

 

[longevitydiary]

Longevity Diary Launches LifeCoin (LFC) – A Cryptocurrency for the Future of Longevity

Project Name: LifeCoin

Token Symbol: LFC

Blockchain: Ethereum

Trading Platform: Uniswap Decentralized Exchange

Contract Address: 0x441C24F018E2Ad266b96f264AF98650c990EA4b1

Initial Price: 1 LFC = 1 USD

Total Supply: Permanently limited, no further issuance (Deflationary Asset)

[What is LifeCoin?]

LifeCoin (LFC) is a cryptocurrency launched by Longevity Diary, designed to create a decentralized, trustworthy, and freely circulating value system within the field of anti-aging and longevity practice.

[Use Cases of LifeCoin]

1️⃣ Purchase Longevity Therapies

Longevity Diary holds breakthrough core technologies in anti-aging, with real-world cases showing life extension rates exceeding 80%. Some therapies are currently undergoing validation for long-term immortality potential. LFC can be directly used to purchase these advanced treatments.

2️⃣ Pay for Health Services & Products

LifeCoin can be used to access Longevity Diary’s health consultation services and anti-aging products developed in-house.

Official Website: http://www.longevitydiary.com

3️⃣ Buy Access to Health Research Data

LFC enables users to purchase cutting-edge health research data.

Data Portal: http://data.longevitydiary.com

4️⃣ Unlock “The Immortality Practice Guide”

Our flagship digital publication, The Immortality Practice Guide, is now available for purchase. Price: 2000 LFC

5️⃣ Payments within Partner Ecosystem

LFC can be used as a payment method with Longevity Diary’s ecosystem partners, helping build an integrated blockchain + health economy.

[Buyback & Value Stabilization Mechanism]

To ensure the long-term value of LFC, Longevity Diary has implemented a permanent buyback mechanism. Users can redeem LFC for fiat currency or therapy services through the official platform at designated prices.Buyback Portal:

http://www.longevity...ngevity/64.html

[Business Cooperation & Inquiries]

We welcome partnership inquiries in the following areas:

Product / Therapy collaboration

Joint development of crypto asset ecosystems

Community promotion / Cross-platform distribution

Official Email: kmpsunny@sina.com

[A Health Revolution for the Web3 Era]

LifeCoin is more than just a token—it’s a bridge connecting cutting-edge science, extended human lifespans, and financial freedom. As humanity pushes the boundaries of longevity, LFC becomes your digital key to mastering longevity assets.

[longevitydiary]

Modify Error， Data Portal: http://databox.longevitydiary.com