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#31 Imminst = pro murder (omega)

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Posted 06 May 2009 - 06:57 AM

Hmmm, I see notice of a NSI brand turmeric reported contaminated with lead http://hairlosshelp....;threadid=76271 and also some about that study being relatively erroneous http://forum.bodybui...p...5661&page=3 but not any reports of fish oil contamination, hard to believe for a molecularly distilled product. That last link states that NSI is owned by Vitacost, interesting.

That's with going through the first 12 pages of a Google search "NSI fish oil contamination." If any one finds corroboration of this claim of NSI fish oil contamination, I would greatly like to see it. Thanks.

#32 ajnast4r

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Posted 06 May 2009 - 07:05 AM

Hmmm, I see notice of a NSI brand turmeric reported contaminated with lead http://hairlosshelp....;threadid=76271 and also some about that study being relatively erroneous http://forum.bodybui...p...5661&page=3 but not any reports of fish oil contamination, hard to believe for a molecularly distilled product. That last link states that NSI is owned by Vitacost, interesting.

That's with going through the first 12 pages of a Google search "NSI fish oil contamination." If any one finds corroboration of this claim of NSI fish oil contamination, I would greatly like to see it. Thanks.



contamination during production seems to be more of an issue than anything else... there have been reports here of everything from bits of metal to slime inside capsules and bottles. why bother using NSI when so many other higher quality alternatives exist as similar priceS?

http://www.iherb.com...tgels/4251?at=0

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#33 Imminst = pro murder (omega)

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Posted 06 May 2009 - 07:31 AM

I need to find some hard core data on this. So far everything I see claims that the NSI brand is superlative.

I see no notice of being molecularly distilled for that iHerb offered product.

Edited by Omega, 06 May 2009 - 07:33 AM.


#34 VespeneGas

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Posted 06 May 2009 - 09:04 AM

I need to find some hard core data on this. So far everything I see claims that the NSI brand is superlative.

I see no notice of being molecularly distilled for that iHerb offered product.


'Hard core data'... like a pubmed study or something? Vitacost has a very bad reputation on these boards, and elsewhere. You get what you pay for.

From the iherb product:

"RxOmega-3 Factors is a pharmaceutical grade fish oil concentrate providing one of the highest potencies of EPA and DHA available. Stringent quality control standards ensure this highly purified fish oil concentrate is free from toxic environmental contaminants and heavy metals like mercury... All Natural Factors products are manufactured in accordance with the Government of Canada's Good Manufacturing Practices (GMP), among the highest standards in the world."




Are NSI's products GMP certified?

#35 Imminst = pro murder (omega)

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Posted 06 May 2009 - 09:40 AM

Jimminy Cricket, you learn something new everyday. Here is a site that rates various suppliers: http://www.thenetana...in-reviews.html

Here is the firm that creates the GMP certifications and NSI is definitely not included: http://www.nsf.org/Certified/GMP/

I'm surprised to see Puritan's Pride so highly rated.

Got to rethink my suppliers for a bunch of stuff now...

Thanks for the heads up!

#36 smithx

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Posted 06 May 2009 - 11:19 AM

I didn't see Vitamin D on your list. Its involvement in depression is equivocal, but it's probably worth trying about 10,000IU a day for a month, then down to 2,000 or 4,000.

Or get your blood levels checked first and go from there.

I used to have depression and I'm not sure what in my supplement regimen got rid of it finally but I have other things in there including 1G of TMG and 500mg of resveratrol.

I also have been taking 1.5G of concentrated DHA fish oil (Super Fisol) a day for years, which is equivalent to about 4G of the non-concentrated stuff.

#37 imarobot

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Posted 06 May 2009 - 04:15 PM

Cut carbs and increase the protein and fat to prevent swings in blood sugar that cause swings in mood.

Take ashwagandha every morning.

And eliminate wheat. The anxiety mentioned below might have more to do with living with the other symptoms of celiac than as a direct result of the disease. The causal relationship is unknown. But in my personal experience, when I eat wheat for one meal (say, a pizza), I have noticably reduced energy for the next few days. Reduced energy for me often equals depression.

Anxiety But Not Depression Decreases in Coeliac Patients After One-Year Gluten-free Diet: A Longitudinal Study

Background: A high prevalence of anxiety and depression has been reported in untreated coeliac disease (CD) patients. At present, the role of a gluten-free diet (GFD) on psychological disorders is still poorly known. The aim of this study was to evaluate state and trait anxiety and depression in adult CD patients before and after 1 year of GFD.

Methods
: A total of 35 CD patients were studied before and after 1 year of GFD. A total of 59 healthy subjects matched for gender, age and socio-economic status were studied as a control group. State and trait anxiety were assessed with the STAI test; depression was assessed using the modified version of the SDS Zung self-rating depression scale (M-SDS). The tests were administered before (T0) and after 1 year of GFD (T1).

Results
: At T0, CD patients showed high levels of state anxiety in a significantly higher percentage compared to controls (71.4% versus 23.7%; P < 0.0001), while there was no significant difference in trait anxiety between groups (25.7% versus 15.2%; P:ns); the percentage of subjects with depression was significantly higher in the CD group than in the control group (57.1% versus 9.6%; P < 0.0001). At T1, a significant decrease in the percentage of state anxiety was found in CD patients (T0: 71.4% versus T1: 25.7%; P < 0.001), while there were no significant changes in the percentage of trait anxiety (T0: 25.7% versus T1: 17.1%; P:ns) or depression (T0: 57.1.% versus T1: 45.7%; P:ns), which was still present in a significantly higher percentage in treated CD compared to controls (P < 0.0001).


Edited by imarobot, 06 May 2009 - 04:20 PM.


#38 mikeh

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Posted 07 May 2009 - 05:48 AM

I want to second the recommendations of cognitive therapy and exercise. Until you build up a habit of regular exercise, you're really missing out on possibly the most important natural mood regulator after healthy sleep habits. First, to put it in chemical terms, think of it as an endless supply of endo-cannabinoids, endorphins, and mental and physical energy with no negative side effects (as long as you don't go wrecking your knees). Also think of your body and brain as a network of tubes and pools where bad chemicals need to get flushed out and fresh air, good chemicals, and nutrients need to be carried in. Exercise is the only way to get enough circulation to move out the stale stuff that's clogging your synapses, and causing secondary inflammation and toxic reactions all over your body.

Getting up the habit is hard when you're depressed. You need to convince yourself that you'll feel better afterwards, even though the thought of getting up and going through the exertion just makes you want to go to sleep. This obstacle won't go away until your body has been convinced, at which point it'll beg you to exercise it. But until then you just need to cling to the idea: my urges tell me to sit here, but I know that those urges are a chemical malfunction that'll be helped in 30 minutes by the exercise.

My strategy for getting past the inertia was to break it down into small actions and accentuate the rewards. My reward was a cup of cocoa afterwards, since cocoa keeps the endo-cannabinoids in circulation longer. Breaking it down into small actions:

- Stand up at your computer and do some squats, or jumping jacks. You'll tire quickly but you'll feel a hint of exhiliration. Seize the moment and take that small amount of adrenaline and run to the next step:
- Find an interesting, maybe even ridiculous activity that you can do for at least 25 minutes. The first few minutes are about overcoming inertia. Then it's about being in a groove. Then after about 25 minutes or so (depending on your fitness level) you'll get your reward: a flood of pleasure chemicals (aka "runners high"). If you can, stick with it until about 40 mins -- that last 15-20 mins really helps it go smoothly the next time (2 days later). If you choose a mildly strenuous activity like house-cleaning instead of going outside to run or whatever, you might not get the high, but you may still get into that groove.

Try for every other day. When you get to the point where you find yourself craving it, seize that moment and start going every day, but do a different activity so you don't exhaust the same muscle group (that leads to burnout).

I'm not saying this is the only answer. But if you're not regulating your body like this, that endless cycle of new drug cocktails is going to keep draining you.

Mental tricks, of convincing yourself to take just one more step, and choosing that step so it gets you incrementally closer to a modest goal, will slowly but surely build up your coping skills and bring you various kinds of relief. Think "Shawshank Redemption". Check out David Allen's "Getting Things Done". Chemicals can be amazing but you sound like you know better than any of us that they're only part of the picture.

BTW I started inching into exercise about 5 years ago, and am only in the last year going to the gym every day. I'm 30 years old, and I never liked sports or exertion. It was only when I realized that "runners high" actually meant "the benefits of marijuana for free and without consequences" that I got interested in exercise, and now I'm more fit than I've ever been, and my mood compared to before is like night and day.

Edited by mikeh, 07 May 2009 - 06:02 AM.


#39 Louise101

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Posted 07 May 2009 - 07:04 AM

THank you to everyone for all the suggestions. Yes, I perhaps am not taking high enough of some supplement etc etc. Regarding exercise, of course you are all right. I KNOW this. As to why I don't make it a higher priority, I guess it is because I hate it. :) But that's a dumb excuse. I get jealous because most of the people around me appear to be able to be fine and dandy, totally happy go lucky without having to exercise. I've tried many forms of exercise (pilates, jogging, tennis, weights, biking, yoga, etc) and I hate them all. LOL But, 7 years ago, I belonged to a gym from May to September and I made myself go every.day. I was on Zoloft at the time, and it didn't completey hold the depression/melancholy at bay. But I totally noticed that I'd feel a definite lift in mood after exercising for 45 mins. I'd walk into the gym feeling like crap and walk out feeling normal. The sadness might return by evening, but at least I'd get a few hours reprieve.

#40 KellyD

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Posted 25 July 2009 - 08:13 PM

Jimminy Cricket, you learn something new everyday. Here is a site that rates various suppliers: http://www.thenetana...in-reviews.html

Here is the firm that creates the GMP certifications and NSI is definitely not included: http://www.nsf.org/Certified/GMP/

I'm surprised to see Puritan's Pride so highly rated.

Got to rethink my suppliers for a bunch of stuff now...

Thanks for the heads up!



Hello, new to the group.

I checked your second link, and found it odd that Puritan's Pride wasn't listed as being GMP certified, even though it's so highly recommended from the first link. I've been found to have elevated arsenic levels...something that we think came from kelp capsules, but has also been found in dessicated liver, fish oil products, and EFA products.

So...it seems like although perhaps they claim to 'follow' GMP certified practices, their company in fact is not GMP certified.

???

Any input/feedback would be sincerely appreciated!

Kelly

Kelly

Could you provide a direct link where you found the info?

#41 AgeVivo

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Posted 25 July 2009 - 08:28 PM

i wonder why there are so many depressions appearently in imminst
either
- some supplements cause depression? that some people would take
- depressed persons are more likely to be on imminst?
- there are many depressions everywhere but it is generally not known?
Any clue?

Edited by AgeVivo, 25 July 2009 - 08:29 PM.


#42 VesperLynd

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Posted 25 July 2009 - 08:28 PM

I battled a tough bout of situational depression last year and relief came in the form of SAM-e which I was later able to taper off and no longer need to use it.

Wishing you the best, VL

#43 StrangeAeons

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Posted 25 July 2009 - 08:37 PM

i wonder why there are so many depressions appearently in imminst
either
- some supplements cause depression? that some people would take
- depressed persons are more likely to be on imminst?
- there are many depressions everywhere but it is generally not known?
Any clue?


ImmInst shows up high on Google when searching for detailed information on supplements. People with depression often turn to supplements for a variety of reasons which I will not go into here; but there's also the fact that depression is fairly common. I came here researching nootropics, hoping to battle the cognitive elements of my depression. Obviously I've learned a whole lot more since then, and supplements aren't even a relevant part of my treatment plan. Still, the appeal of supplements (especially over medicatons) is obvious if perhaps not always well-informed. Even normally euthymic people have brief episodes of depression-- as to whether these reach clinical significance, warrant treatment of any sort, or require intervention... well that's a whole different story.

#44 KellyD

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Posted 26 July 2009 - 02:05 AM

"Here is the firm that creates the GMP certifications and NSI is definitely not included: http://www.nsf.org/Certified/GMP/ "

A p.s. to my original post:

After searching later this afternoon by street address, NSI (the Vitacost brand) IS actually on the list:

NUTRACEUTICAL LIFE SCIENCES
NORTHWEST 5400 BROKEN SOUND BOULEVARD
BOCA RATON, FL 33487
561-982-4180


FACILITY:

NUTRACEUTICAL LIFE SCIENCES INSTITUTE
130 LEXINGTON PARKWAY
LEXINGTON, NC 27295

Same address as on the bottle of coQ10 I found in the back of my cupboard.

So...they must've gotten their act together after that 2004 report of lead in their turmeric.

???

#45 AgeVivo

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Posted 26 July 2009 - 03:28 PM

ImmInst shows up high on Google when searching for detailed information on supplements. People with depression often turn to supplements

Thank you for the answer, it makes sense. I thought there were 8000+ people in imminst interested in life extension, but when chating about life extension or looking for life-extention project-participants many people answer with supplements and anti-depression stuff. I hope that imminst is not about 50 life-extension people plus 7950+ people looking for anti-depression supplements. I read recently that there could be a specific forum about depression; perhaps it would allow to better see who is interested in life extension.

#46 Axl

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Posted 27 July 2009 - 12:02 AM

Hi I've been diagnosed with major depression and have been taking antidepressants on and off for 4 years.

As others have suggested, try Deprenyl aka L-Deprenyl aka Deprenil aka Selegiline.


Works for me:

- 30-60 minutes a day of aerobic exercise

- deprenyl sublingual liquid

- sometimes (1-2 days a week) a mild stimulant such as sudafed (pseudoephedrine) or caffeine or low-dose modafinil

- finding a job where 7-8 hour days are the norm rather than 9+ hour days, since employment is my greatest source of stress


Somewhat works for me:

- trazodone and mirtazapine taken around 8pm at night gave me a deeper sleep, but unfortunate side effect was weight gain

- benadryl (diphenhydramine) seems to work sometimes and not work others. note prozac was derived from this antihistamine.


Doesn't work for me:

- prozac and zoloft and celexa all cause my skin to itch after 2-4 weeks

- paxil makes me sleepy 24 hours a day *and* causes weight gain

- lexapro has little to no effect although it has been suggested my dose was too low

- cymbalta and elavil have no effect whatsoever at any dose

- wellbutrin seems to work but has addictive quality where I crave higher and higher dose so I needed to stop


It's an ongoing process so good luck.

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#47 Proconsul

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Posted 28 July 2009 - 11:49 AM

Hi Louise! I understand you, I have suffered from depression since I was a child. I have been on SSRI for 12 years now. I have tried different combinations. The most effective drug for me is paroxetin. Presently I'm taking 40 mg a day, combined with 20-40 mg fluoxetin. I tried other stuff as well, like Effexor, but they were not very satisfactory. I have also experienced weigth gain, but this was not a big problem since I have always been very skinny - and I suspect my low weight was caused by some imbalance related to my depression. Anyway, I went up from about 65 - 67 kg to around 80, which was a bit too much for my kind of body structure. I have tried several diets without suiccess, until in the last year I found one that worked. Basically I fast every other day eating only fruit, sallads, perhaps some yoghurt. The reamaining days I eat as I like, but try not to exaggerate with carbs and to include always a lot of veggies and fruit. This diet is easy to follow, and in less than one year I dropped back to around 70 kg, which is actually less than I had planned (I'm 182 cm - about 6 feet - tall). So I think it's possible to control weight even taking SSRI. I recommend you to try new combinations with the help of a good psychiatrist (don't experiment by yourself, coz it could be really dangerous). I would also suggest to try cognitive/behavior therapy, which seems to be one of the best treatment against depression. Good luck!




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